Patents by Inventor Jan T. Vilcek

Jan T. Vilcek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Treating TNF-alpha-Mediated Diseases Using Chimeric TNF-alpha Antibodies
    Publication number: 20140212413
    Abstract: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-? (TNF?) and are useful in vivo diagnosis and therapy of a number of TNF?-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
    Type: Application
    Filed: January 17, 2014
    Publication date: July 31, 2014
    Applicants: New York University, Janssen Biotech, Inc.
    Inventors: Junming Le, Jan T. Vilcek, Peter E. Daddona, John Ghrayeb, David M. Knight, Scott A. Siegel
  • Methods of Treating Ankylosing Spondylitis Using Anti-TNF Antibodies and Peptides of Human Tumor Necrosis Factor
    Publication number: 20110195063
    Abstract: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-? (TNF?) and are useful in vivo diagnosis and therapy of a number of TNF?-mediated pathologies and conditions, including ankylosing spondylitis, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
    Type: Application
    Filed: September 17, 2010
    Publication date: August 11, 2011
    Applicants: Centocor, Inc., New York University
    Inventors: Junming Le, Jan T. Vilcek, Peter E. Daddona, John Ghrayeb, David M. Knight, Scott A. Siegel, David J. Shealy
  • Methods of treating ankylosing spondylitis using anti-TNF antibodies and peptides of human tumor necrosis factor
    Publication number: 20090041762
    Abstract: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-? (TNF?) and are useful in vivo diagnosis and therapy of a number of TNF?-mediated pathologies and conditions, including ankylosing spondylitis, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
    Type: Application
    Filed: December 13, 2005
    Publication date: February 12, 2009
    Inventors: Junming Le, Jan T. Vilcek, Peter E. Daddona, John Ghrayeb, David M. Knight, Scott A. Siegel, David J. Shealy
  • Human gamma interferon polypeptide having glutamine as the ninth n-terminal amino acid
    Patent number: 4835256
    Abstract: Disclosed is a novel DNA which shows complementarity to human interferon-.gamma. mRNA, a recombinant plasmid containing the DNA, a microorganism containing the recombinant plasmid and a method of producing the same as well as a process for producing a polypeptide having human interferon.gamma. activity using the microorganism.
    Type: Grant
    Filed: December 3, 1987
    Date of Patent: May 30, 1989
    Assignees: New York University & Juridical Foundation, Japanese Foundation for Cancer Research
    Inventors: Tadatsugu Taniguchi, Haruo Sugano, Tatsunari Nishi, Jan T. Vilcek, Yum K. Yip
  • Method of enhancing the production of human .gamma. Interferon
    Patent number: 4460685
    Abstract: A method for stimulating the production of human IFN-.gamma. in a culture of cells is disclosed. In this method, an effective amount of a diterpene compound is added to a culture of IFN-.gamma. producing cells.
    Type: Grant
    Filed: April 17, 1981
    Date of Patent: July 17, 1984
    Assignee: New York University
    Inventors: Jan T. Vilcek, Yum K. Yip