Patents by Inventor Jan ten Broeke

Jan ten Broeke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6256243
    Abstract: A monolithically integrated test circuit for testing a digital semiconductor circuit configuration that is formed on the same semiconductor chip and has a large number of elements to be tested. The test circuit has a test data pattern register for temporary storage of a test data pattern, a read and write circuit for writing and reading the data in the test data pattern register to and from the elements to be tested, and a comparison circuit. The comparison circuit tests for any difference between the data written to and read from the elements to be tested. The test circuit has a pattern variation circuit, which can be activated by an activation signal and varies the test data pattern from the test data pattern register before writing into the elements to be tested.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: July 3, 2001
    Assignee: Infineon Technologies AG
    Inventors: Dominique Savignac, Wolfgang Nikutta, Michael Kund, Jan Ten Bröke
  • Patent number: 5049548
    Abstract: Renin-inhibitory di-, tri-, and tetrapeptides of the formula I:A-B-E-G-T-Jin whichA is heterocyclic, substituted heterocyclic etc;B is --N(A.sup.1)CH[(CH.sub.2).sub.2 R.sup.3 ]CO--,E is absent or is --N(A.sup.2)CH[(CH.sub.2).sub.2 R.sup.4 ]CO--;G is ##STR1## and J is --Y--(CH.sub.2).sub.x [CH(R.sup.5)].sub.y --(CH.sub.2).sub.z --R.sup.10and pharmaceutically acceptable salts thereof are disclosed. These compounds inhibit renin and are useful for treating various forms of renin-associated hypertension, hyperaldosteronism and congestive heart failure; compositions containing these renin-inhibitory peptides, optionally with other antihypertensive agents; and methods of treating hypertension, hyperaldosteronism or congestive heart failure or of establishing renin as a causative factor in these problems which employ these novel peptides.
    Type: Grant
    Filed: March 3, 1989
    Date of Patent: September 17, 1991
    Assignee: Merck & Co., Inc.
    Inventors: William J. Greenlee, Jan ten Broeke
  • Patent number: 4232026
    Abstract: Certain 2- and/or 9- phenylalkyl-5,11-dimethyl-5,11-diazaditwistane compounds bind to opiate receptor sites and have central nervous system activities exemplified by analgesia.
    Type: Grant
    Filed: July 20, 1978
    Date of Patent: November 4, 1980
    Assignee: Merck & Co., Inc.
    Inventor: Jan ten Broeke
  • Patent number: 4070360
    Abstract: A new heterocycle, 5,11-diazatetracyclo-[6.2.2.0.sup.2,7.0.sup.4,9 ]dodecane, is prepared by heating an endo-diazatricyclo[6.2.2.0.sup.2,7 ]dodec-11-ene substituted in the 7 and 11 positions with electron withdrawing groups. 2,9-Bis-phenylacetyl derivatives of the new heterocycle and closely related derivatives are potent analgesic agents.
    Type: Grant
    Filed: March 24, 1977
    Date of Patent: January 24, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Jan ten Broeke, Edward J. J. Grabowski, Lars M. Flataker, Michael H. Fisher, Arthur A. Patchett
  • Patent number: 4070359
    Abstract: A new heterocycle, 5,11-diazatetracyclo]6.2.2.0.sup.2,7.0.sup.4,9 ]dodecane, is prepared by heating an endo-diazatricyclo[6.2.2.0.sup.2,7 ]dodec-11-ene substituted in the 7 and 11 positions with electron withdrawing groups. 2,9-Bis-phenylacetyl derivatives of the new heterocycle and closely related derivatives are potent analgesic agents.
    Type: Grant
    Filed: March 24, 1977
    Date of Patent: January 24, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Jan ten Broeke, Edward J. J. Grabowski, Lars M. Flataker, Michael H. Fisher, Arthur A. Patchett
  • Patent number: 4033968
    Abstract: A new heterocycle, 5,11-diazatetracyclo[6.2.2.0.sup.2,7.0.sup.4.9 ]dodecane, is prepared by heating an endo-diazatricyclo[6.2.2.0.sup.2,7 ]dodec-11-ene substituted in the 7 and 11 positions with electron withdrawing groups. 2,9-Bis-phenylacetyl derivatives of the new heterocycle and closely related derivatives are potent analgesic agents.
    Type: Grant
    Filed: April 14, 1976
    Date of Patent: July 5, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Jan ten Broeke, Edward J. J. Grabowski, Lars M. Flataker, Michael H. Fisher, Arthur A. Patchett