Patents by Inventor Jan Tois

Jan Tois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND ASSEMBLIES FOR SELECTIVELY DEPOSITING TRANSITION METALS
    Publication number: 20240096633
    Abstract: The disclosure relates to methods of selectively depositing material comprising a group 3 to 6 transition metal on a first surface of a substrate relative to a second surface of the substrate by a cyclic deposition process. The method includes providing a substrate in a reaction chamber, providing a transition metal precursor into the reaction chamber in a vapor phase, wherein the transition metal precursor comprises an aromatic ligand and providing a second precursor into the reaction chamber in a vapor phase to deposit transition metal on the first surface of the substrate. The disclosure further relates to a transition metal layers, and to deposition assemblies.
    Type: Application
    Filed: September 13, 2023
    Publication date: March 21, 2024
    Inventors: Elina Färm, Jan Willem Maes, Charles Dezelah, Shinya Iwashita, Arpita Saha, Eva Tois, Marko Tuominen, Janne-Petteri Niemelä, Patricio Eduardo Romero, Chiyu Zhu, Glen Wilk, Holger Saare, YoungChol Byun, Jonahtan Bakke
  • CRYSTALLINE FORM OF A BET-INHIBITOR AND MANUFACTURE THEREOF
    Publication number: 20220204493
    Abstract: The present invention relates to crystalline form 1 of 6-(3, 5-dimethylisoxazol-4-yl)-7-methoxy-3-methyl-1-(pyridin-2-ylmethyl)quinolin-2(1H)-one (I) and to a method of manufacture thereof. Compound (I) is a BET inhibitor useful in the treatment of cancer.
    Type: Application
    Filed: April 9, 2020
    Publication date: June 30, 2022
    Inventors: Eila LUUKKONEN, Anna STAFFANS, Jan TOIS, Chandrasekhar ABBINENI, Roshaiah MARLA
  • Synthesis of 2-indolinone derivatives
    Patent number: 11261158
    Abstract: The present disclosure relates to a preparation method of methyl (E)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate from methyl 2-oxoindoline-6-carboxylate using high reaction temperatures and a reaction solvent enabling azeotropic removal of acetic acid during the reaction.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: March 1, 2022
    Assignee: FERMION OY
    Inventors: Antti Piisola, Jan Tois
  • SYNTHESIS OF 2-INDOLINONE DERIVATIVES
    Publication number: 20200299275
    Abstract: The present disclosure relates to a preparation method of methyl (E)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate from methyl 2-oxoindoline-6-carboxylate using high reaction temperatures and a reaction solvent enabling azeotropic removal of acetic acid during the reaction.
    Type: Application
    Filed: November 2, 2018
    Publication date: September 24, 2020
    Applicant: Fermion Oy
    Inventors: Antti PIISOLA, Jan TOIS
  • Process for the preparation of ospemifene
    Patent number: 9321712
    Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: April 26, 2016
    Assignee: FERMION OY
    Inventors: Jan Tois, Ainoliisa Pihko, Arne Grumann
  • A PROCESS FOR THE PREPARATION OF OSPEMIFENE
    Publication number: 20150321983
    Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2[4-(4-chloro-1,2-diphen-yl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
    Type: Application
    Filed: October 17, 2013
    Publication date: November 12, 2015
    Applicant: Fermion Oy
    Inventor: Jan TOIS
  • PROCESS FOR THE PREPARATION OF OSPEMIFENE
    Publication number: 20150274624
    Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
    Type: Application
    Filed: October 17, 2013
    Publication date: October 1, 2015
    Applicant: Fermion Oy
    Inventors: Jan Tois, Ainoliisa Pihko, Arne Grumann