Patents by Inventor Jan Tois

Jan Tois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of cleaning a surface
    Patent number: 12217954
    Abstract: Methods for cleaning a substrate are disclosed. The substrate comprises a dielectric surface and a metal surface. The methods comprise providing a cleaning agent to the reaction chamber.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: February 4, 2025
    Assignee: ASM IP Holding B.V.
    Inventors: Shaoren Deng, Andrea Illiberi, Daniele Chiappe, Eva Tois, Giuseppe Alessio Verni, Michael Givens, Varun Sharma, Chiyu Zhu, Shinya Iwashita, Charles Dezelah, Viraj Madhiwala, Jan Willem Maes, Marko Tuominen, Anirudhan Chandrasekaran
  • CRYSTALLINE FORM OF A BET-INHIBITOR AND MANUFACTURE THEREOF
    Publication number: 20220204493
    Abstract: The present invention relates to crystalline form 1 of 6-(3, 5-dimethylisoxazol-4-yl)-7-methoxy-3-methyl-1-(pyridin-2-ylmethyl)quinolin-2(1H)-one (I) and to a method of manufacture thereof. Compound (I) is a BET inhibitor useful in the treatment of cancer.
    Type: Application
    Filed: April 9, 2020
    Publication date: June 30, 2022
    Inventors: Eila LUUKKONEN, Anna STAFFANS, Jan TOIS, Chandrasekhar ABBINENI, Roshaiah MARLA
  • Synthesis of 2-indolinone derivatives
    Patent number: 11261158
    Abstract: The present disclosure relates to a preparation method of methyl (E)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate from methyl 2-oxoindoline-6-carboxylate using high reaction temperatures and a reaction solvent enabling azeotropic removal of acetic acid during the reaction.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: March 1, 2022
    Assignee: FERMION OY
    Inventors: Antti Piisola, Jan Tois
  • SYNTHESIS OF 2-INDOLINONE DERIVATIVES
    Publication number: 20200299275
    Abstract: The present disclosure relates to a preparation method of methyl (E)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate from methyl 2-oxoindoline-6-carboxylate using high reaction temperatures and a reaction solvent enabling azeotropic removal of acetic acid during the reaction.
    Type: Application
    Filed: November 2, 2018
    Publication date: September 24, 2020
    Applicant: Fermion Oy
    Inventors: Antti PIISOLA, Jan TOIS
  • Process for the preparation of ospemifene
    Patent number: 9321712
    Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: April 26, 2016
    Assignee: FERMION OY
    Inventors: Jan Tois, Ainoliisa Pihko, Arne Grumann
  • A PROCESS FOR THE PREPARATION OF OSPEMIFENE
    Publication number: 20150321983
    Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2[4-(4-chloro-1,2-diphen-yl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
    Type: Application
    Filed: October 17, 2013
    Publication date: November 12, 2015
    Applicant: Fermion Oy
    Inventor: Jan TOIS
  • PROCESS FOR THE PREPARATION OF OSPEMIFENE
    Publication number: 20150274624
    Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
    Type: Application
    Filed: October 17, 2013
    Publication date: October 1, 2015
    Applicant: Fermion Oy
    Inventors: Jan Tois, Ainoliisa Pihko, Arne Grumann