Patents by Inventor Jan Tois

Jan Tois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of 2-indolinone derivatives
    Patent number: 11261158
    Abstract: The present disclosure relates to a preparation method of methyl (E)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate from methyl 2-oxoindoline-6-carboxylate using high reaction temperatures and a reaction solvent enabling azeotropic removal of acetic acid during the reaction.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: March 1, 2022
    Assignee: FERMION OY
    Inventors: Antti Piisola, Jan Tois
  • Process for the preparation of ospemifene
    Patent number: 9321712
    Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: April 26, 2016
    Assignee: FERMION OY
    Inventors: Jan Tois, Ainoliisa Pihko, Arne Grumann
  • PROCESS FOR THE PREPARATION OF OSPEMIFENE
    Publication number: 20150274624
    Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
    Type: Application
    Filed: October 17, 2013
    Publication date: October 1, 2015
    Applicant: Fermion Oy
    Inventors: Jan Tois, Ainoliisa Pihko, Arne Grumann