Patents by Inventor Jan Van Doorn

Jan Van Doorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030165821
    Abstract: A method for detection and/or identification of HPV present in a biological sample comprising amplification of HPV polynucleic acids and of hybridization of said amplified polynucleic acids to a number of probes whereby a short fragment of the L1 gene of HPV is amplified after which, the amplimers are contacted with probes that specifically hybridize to the said short fragment of the L1 gene of at least one HPV type and a diagnostic kit to perform said method and primers and probes used in the said method.
    Type: Application
    Filed: September 11, 2002
    Publication date: September 4, 2003
    Applicant: INNOGENETICS S.A.
    Inventors: Leen-Jan Van Doorn, Wim Quint, Bernhard Kleter, Jan Ter Schegget
  • Publication number: 20030152591
    Abstract: The present invention relates to genomic nucleotide sequences and amino acid sequences corresponding to the non-coding and coding region of a new type of HCV. The invention relates to new HCV types and subtypes sequences which are different from the known HCV types and subtypes sequences. Particularly, the present invention relates to said new HCV type sequences; a process for preparing them, and their use for diagnosis, prophylaxis and therapy. More particularly, the present invention provides new type-specific sequences of the 5′ NCR, Core, the E1 and the NS5 regions of the new HCV type. These new HCV sequences are useful to diagnose the presence of HCV type genotypes or serotypes in a biological sample. Moreover, the availability of these new type-specific sequences can increase the overall sensitivity of HCV detection and should also prove to be useful for prophylactic and therapeutic purposes.
    Type: Application
    Filed: August 29, 2002
    Publication date: August 14, 2003
    Inventors: Erwin Sablon, Leen-Jan Van Doorn, Wim Quint
  • Patent number: 6482588
    Abstract: The present invention relates to a method for detection and/or identification of HPV present on a biological sample, comprising the steps of amplification of HPV polynucleic acids and of hybridization of said amplified ploynucleic acids to a number of probes. By means of PCR, a short fragment of the L1 gene of HPV is amplified. The amplimers are then contacted with probes that specifically hybridize to said short fragment of the L1 gene of either one or more than one HPV type. A preferred format is the reverse hybridization technique, more particularly the LiPA technique. The invention also relates to primers and probes to be used in a method of detection and/or identification of HPV and to a diagnostic kit to perform said method.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: November 19, 2002
    Assignee: Innogenetics S.A.
    Inventors: Leen-Jan Van Doorn, Wim Quint, Berhnard Kleter, Jan TerSchegget
  • Patent number: 6221582
    Abstract: The invention relates to the use of the GTPase gene family as a target for nucleic acid based assays for the detection and differentiation of prokaryotic organisms. The invention relates to polynucleic acids derived from gene sequences encoding prokaryotic GTPase (=GTP-binding) proteins, as well as their use in the detection and identification of prokaryotic organisms; primers and probes derived from said polynucleic acid sequences, for specific amplification and detection of prokaryotic DNA in a biological sample; as well as methods and kits allowing the detection and identification of at least one micoroorganism, and preferentially several microorganisms simultaneously in a sample. More specifically, the invention relates to new polynucleic acid sequences encoding GTPase proteins from Campylobacter species, primers and probes derived from them, and methods and kits comprising these reagents for the detection and differentiation of species belonging to the genus Campylobacter.
    Type: Grant
    Filed: August 7, 1997
    Date of Patent: April 24, 2001
    Assignees: Innogenetics N.V., Delft Diagnostic Laboratory B.V.
    Inventors: Belinda Giesendorf, Wilhelmus Quint, Leendert-Jan Van Doorn