Abstract: A method for identifying an agent that has an influence on the amount of an analyte expressed by a cell, said method comprising stimulating a cell to produce at least 2 analytes, forming, in the absence and in the presence of a candidate compound, on the pins of a matrix at least 2 recognition complexes between an analyte and a recognition molecule, treating said recognition complexes with detection molecules to obtain on the pins of the matrix detection complexes, determining each amount of each detection complex formed on the pins, comparing each amount of detection complex formed in the absence and in the presence of a candidate compound, and choosing a candidate compound which has an influence on the amount of at least one of the detection complexes formed as a pharmaceutical agent.

Abstract: By providing an elastic form stable material which is capable of being delivered directly into the body tissue in the vicinity of or surrounding the lower esophagus of a living creature, gastroesophageal reflux disease is able to be effectively treated. In the preferred method, the elastic form stable material is injected directly into lower esophagus and allowed to cure in situ, thereby achieving the desired result.

Abstract: A device for preparing and ejecting polymeric cement made from at least two pre-packaged components comprises a tubular vessel including a first axial end wall having a closed outlet, and a second axial end wall having an aperture. A first starting component of the polymeric cement is present inside said tubular vessel near the first axial end wall. A shaft extends through said aperture of the second axial end wall. A piston element comprises a closed container filled with a second starting component of the polymeric cement. The piston element is selectively lockable to the shaft. The container has a bore and is slidingly engaged upon said shaft. An agitator element is secured to one end of the shaft. Furthermore opening means for providing an opening in the closed container are provided.