Patents by Inventor Jan W. H. Smeets

Jan W. H. Smeets has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective N-acylation of amino alcohols
    Patent number: 5631356
    Abstract: The present invention provides an efficient method for the production of N-acyl amino alcohols via the selective acylation of the free amines of amino alcohols by reacting with an organic acid or a salt thereof with an alkyl sulfonyl chloride or an alkyl phenyl sulfonyl chloride, in an organic solvent and in the presence of an organic base, to form the corresponding mixed anhydride, followed by reacting the mixed anhydride with an amino alcohol or a salt thereof to form the corresponding N-acyl amino alcohol.
    Type: Grant
    Filed: December 1, 1994
    Date of Patent: May 20, 1997
    Assignee: Gist-brocades, N.V.
    Inventors: Jan W. H. Smeets, Pieter G. Weber
  • Enzymatic synthesis of ceramides and hybrid ceramides
    Patent number: 5610040
    Abstract: The present invention provides an efficient method for the production of ceramides and hybrid ceramides via the selective N-acylation of glycosphingolipids by reacting an organic acid or ester thereof with a lysosphingolipid in the presence of a lipase in an organic medium.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: March 11, 1997
    Assignee: Gist-brocades, n.v.
    Inventors: Jan W. H. Smeets, Robertus M. De Pater, Johannes W. J. Lambers