Patents by Inventor Jan-Willi Janiesch

Jan-Willi Janiesch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing a functional synthetic cell in form of a giant unilamellar vesicle
    Patent number: 11389408
    Abstract: The present invention relates to a method for preparing a protocell in form of a giant unilamellar vesicle, which comprises the following steps: a) providing a water-based droplet encapsulated by an outer polymer shell, which borders the inner space of the droplet, wherein the droplet has a maximum dimension of 0.5 ?m to 1,000 ?m, wherein the inner space of the droplet contains at least one lipid, b) transforming the lipid content of the droplet into a lipid bilayer which is arranged at and covers the inner surface of the polymer shell and oil phase in order to form a polymer shell-stabilized giant unilamellar vesicle, c) optionally incorporating one or more proteins and/or nuclei into the polymer shell-stabilized giant unilamellar vesicle provided in step b) and d) optionally removing the polymer shell and oil phase from the polymer shell-stabilized giant unilamellar vesicle and optionally transferring it from the oil to the water phase.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: July 19, 2022
    Inventors: Joachim P. Spatz, Lucia T. Benk, Johannes Patrick Frohnmayer, Barbara Haller, Jan-Willi Janiesch, Yilia Plazman, Marian Weiss
  • A Method for Preparing a Functional Synthetic Cell in Form of a Giant Unilamellar Vesicle
    Publication number: 20200170949
    Abstract: The present invention relates to a method for preparing a protocell in form of a giant unilamellar vesicle, which comprises the following steps: a) providing a water-based droplet encapsulated by an outer polymer shell, which borders the inner space of the droplet, wherein the droplet has a maximum dimension of 0.5 ?m to 1,000 ?m, wherein the inner space of the droplet contains at least one lipid, b) transforming the lipid content of the droplet into a lipid bilayer which is arranged at and covers the inner surface of the polymer shell and oil phase in order to form a polymer shell-stabilized giant unilamellar vesicle, c) optionally incorporating one or more proteins and/or nuclei into the polymer shell-stabilized giant unilamellar vesicle provided in step b) and d) optionally removing the polymer shell and oil phase from the polymer shell-stabilized giant unilamellar vesicle and optionally transferring it from the oil to the water phase.
    Type: Application
    Filed: June 6, 2018
    Publication date: June 4, 2020
    Inventors: Joachim P. Spatz, Lucia T. Benk, Johannes Patrick Frohnmayer, Barbara Haller, Jan-Willi Janiesch, Yilia Plazman, Marian Weiss