Patents by Inventor Jan Wouter Drijfhout

Jan Wouter Drijfhout has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOACTIVE PEPTIDES DERIVED FROM SNAKES
    Publication number: 20230391839
    Abstract: The disclosure concerns snake-derived peptides and the useful application of such peptides to inhibit bacterial, fungal, viral and parasitic infections. The disclosed peptides are also useful for the treatment of an inflammatory condition or cancers.
    Type: Application
    Filed: May 23, 2023
    Publication date: December 7, 2023
    Inventors: Harald Martijn Ijsbrand Kerkkamp, Michael Keith Richardson, Gilles Philippus van Wezel, Jan Wouter Drijfhout, Robert Alexander Cordfunke, Michella Manon Voet, Petrus Hendricus Nibbering
  • Bioactive peptides derived from snakes
    Patent number: 11680088
    Abstract: The disclosure concerns snake-derived peptides and the useful application of such peptides to inhibit bacterial, fungal, viral and parasitic infections. The disclosed peptides are also useful for the treatment of an inflammatory condition or cancers.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: June 20, 2023
    Assignees: Universiteit Leiden, Academisch Ziekenhuis Leiden h.o.d.n. LUMC
    Inventors: Harald Martijn Ijsbrand Kerkkamp, Michael Keith Richardson, Gilles Philippus van Wezel, Jan Wouter Drijfhout, Robert Alexander Cordfunke, Michella Manon Voet, Petrus Hendricus Nibbering
  • BIOACTIVE PEPTIDES DERIVED FROM SNAKES
    Publication number: 20220064231
    Abstract: The disclosure concerns snake-derived peptides and the useful application of such peptides to inhibit bacterial, fungal, viral and parasitic infections. The disclosed peptides are also useful for the treatment of an inflammatory condition or cancers.
    Type: Application
    Filed: September 17, 2019
    Publication date: March 3, 2022
    Inventors: Harald Martijn Ijsbrand Kerkkamp, Michael Keith Richardson, Gilles Philippus van Wezel, Jan Wouter Drijfhout, Robert Alexander Cordfunke, Michella Manon Voet, Petrus Hendricus Nibbering
  • Compositions and methods for the diagnosis of rheumatoid arthritis
    Patent number: 10684284
    Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: June 16, 2020
    Assignees: Inova Diagnostics, Inc., Leiden University Medical Center
    Inventors: Michael Mahler, Leendert A. Trouw, Jan Wouter Drijfhout, Tom Huizinga, René Toes, Peter Van Veelen
  • PRAME derived peptides and immunogenic compositions comprising these
    Patent number: 10450356
    Abstract: The invention relates to a peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein and to its use as such or in a composition as a medicament for the treatment and/or prevention of cancer.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: October 22, 2019
    Assignee: ACADEMISCH ZIEKENHUIS LEIDEN H.O.D.N. LUMC
    Inventors: Jan Kessler, Marieke Griffioen, Cornelis Johannes Maria Melief, Jan Wouter Drijfhout
  • METHOD OF DETECTING AUTO-ANTIBODIES FROM PATIENTS SUFFERING FROM RHEUMATOID ARTHRITIS, A PEPTIDE AND ASSAY KIT
    Publication number: 20190056393
    Abstract: Peptides useful in determining the presence of autoantibodies in patients suffering from rheumatoid arthritis are disclosed.
    Type: Application
    Filed: November 2, 2018
    Publication date: February 21, 2019
    Applicant: STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN
    Inventors: Waltherus Jacobus Wilhelmus VAN VENROOIJ, Jan Wouter DRIJFHOUT, Martinus Adrianus Maria VAN BOEKEL, Gerardus Jozef Maria PRUIJN
  • Antimicrobial peptide and uses thereof
    Patent number: 10130677
    Abstract: The invention relates to antimicrobial peptides, pharmaceutical compositions comprising the peptides and to uses thereof for in the treatment or prevention of microbial, bacterial, fungal, viral and parasitic infection.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: November 20, 2018
    Assignees: Academisch Ziekenhuis Leiden h.o.d.n. LUMC, Academisch Medisch Centrum
    Inventors: Petrus Hendricus Nibbering, Anna de Breij, Robert Alexander Cordfunke, Sebastianus Antonius Johannes Zaat, Jan Wouter Drijfhout
  • Method of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and assay kit
    Patent number: 10119966
    Abstract: Peptides useful in determining the presence of autoantibodies in patients suffering from rheumatoid arthritis are disclosed.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: November 6, 2018
    Assignee: STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN
    Inventors: Waltherus Jacobus Wilhelmus Van Venrooij, Jan Wouter Drijfhout, Martinus Adrianus Maria Van Boekel, Gerardus Jozef Maria Pruijn
  • COMPOSITIONS AND METHODS FOR THE DIAGNOSIS OF RHEUMATOID ARTHRITIS
    Publication number: 20180038856
    Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.
    Type: Application
    Filed: October 23, 2017
    Publication date: February 8, 2018
    Inventors: Michael MAHLER, Leendert A. TROUW, Jan Wouter DRIJFHOUT, Tom HUIZINGA, René TOES, Peter VAN VEELEN
  • Compositions and methods for the diagnosis of rheumatoid arthritis
    Patent number: 9829489
    Abstract: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: November 28, 2017
    Assignees: INOVA DIAGNOSTICS, INC., LEIDEN UNIVERSITY MEDICAL CENTER
    Inventors: Michael Mahler, Leendert A Trouw, Jan Wouter Drijfhout, Tom Huizinga, René Toes, Peter Van Veelen
  • METHOD OF DETECTING AUTO-ANTIBODIES FROM PATIENTS SUFFERING FROM RHEUMATOID ARTHRITIS, A PEPTIDE AND ASSAY KIT
    Publication number: 20170269078
    Abstract: Peptides useful in determining the presence of autoantibodies in patients suffering from rheumatoid arthritis are disclosed.
    Type: Application
    Filed: May 31, 2017
    Publication date: September 21, 2017
    Applicant: STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN
    Inventors: Waltherus Jacobus Wilhelmus VAN VENROOIJ, Jan Wouter DRIJFHOUT, Martinus Adrianus Maria VAN BOEKEL, Gerardus Jozef Maria PRUIJN
  • Method of detecting auto-antibodies from patients suffering from rheumatoid arthritis, a peptide and an assay kit
    Patent number: 9689871
    Abstract: Peptides useful in determining the presence of autoantibodies in patients suffering from rheumatoid arthritis are disclosed.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: June 27, 2017
    Assignee: STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN
    Inventors: Waltherus Jacobus Wilhelmus Van Venrooij, Jan Wouter Drijfhout, Martinus Adrianus Maria Van Boekel, Gerardus Jozef Maria Pruijn
  • Antimicrobial peptide
    Patent number: 9562085
    Abstract: The disclosure relates to antimicrobial peptides, pharmaceutical compositions comprising the peptides and to uses thereof for treatment or prevention of microbial, bacterial, fungal, viral and parasitic infection.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: February 7, 2017
    Assignee: Academisch Ziekenhuis Leiden H.O.D.N. LUMC
    Inventors: Petrus Hendricus Nibbering, Pieter Hiemstra, Jan Wouter Drijfhout
  • Peptides, conjugates and method for increasing immunogenicity of a vaccine
    Patent number: 9522962
    Abstract: The present invention relates to conjugates comprising a peptide of at least 10 amino acid residues comprising the amino acid sequence GITELKKL (residues 383-390 of SEQ ID NO: 3) for induction of potent humoral and cellular immune responses when administered to subjects having antibodies against tetanus toxoid. In one embodiment the invention relates to a prophylactic and therapeutic vaccine and in a further embodiment the invention relates to the treatment or prevention of cancer or an infectious disease.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: December 20, 2016
    Assignees: Academisch Ziekenhuis Leiden h.o.d.n. LUMC, Stichting voor de Technische Wetenschappen
    Inventors: Ferdinand Antonius Ossendorp, Cornelis Joseph Maria Melief, Jan Wouter Drijfhout
  • PRAME DERIVED PEPTIDES AND IMMUNOGENIC COMPOSITIONS COMPRISING THESE
    Publication number: 20160333065
    Abstract: The invention relates to a peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein and to its use as such or in a composition as a medicament for the treatment and/or prevention of cancer.
    Type: Application
    Filed: August 4, 2016
    Publication date: November 17, 2016
    Applicant: Academisch Ziekenhuis Leiden H.O.D.N. LUMC
    Inventors: Jan KESSLER, Marieke GRIFFIOEN, Cornelis Johannes Maria MELIEF, Jan Wouter DRIJFHOUT
  • Antimicrobial Peptide and Uses Thereof
    Publication number: 20160317611
    Abstract: The invention relates to antimicrobial peptides, pharmaceutical compositions comprising the peptides and to uses thereof for in the treatment or prevention of microbial, bacterial, fungal, viral and parasitic infection.
    Type: Application
    Filed: December 12, 2014
    Publication date: November 3, 2016
    Applicants: Academisch Ziekenhuis Leiden h.o.d.n. LUMC, Academisch Medisch Centrum
    Inventors: Petrus Hendricus Nibbering, Anna de Breij, Robert Alexander Cordfunke, Sebastianus Antonius Johannes Zaat, Jan Wouter Drijfhout
  • Prame derived peptides and immunogenic compositions comprising these
    Patent number: 9441025
    Abstract: The invention relates to a peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein and to its use as such or in a composition as a medicament for the treatment and/or prevention of cancer.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: September 13, 2016
    Assignee: Academisch Ziekenhuis Leiden H.O.D.N. LUMC
    Inventors: Jan Kessler, Marieke Griffioen, Cornelis Johannes Maria Melief, Jan Wouter Drijfhout
  • ANTIMICROBIAL PEPTIDE
    Publication number: 20160075749
    Abstract: The disclosure relates to antimicrobial peptides, pharmaceutical compositions comprising the peptides and to uses thereof for treatment or prevention of microbial, bacterial, fungal, viral and parasitic infection.
    Type: Application
    Filed: May 9, 2014
    Publication date: March 17, 2016
    Inventors: Petrus Hendricus Nibbering, Pieter Hiemstra, Jan Wouter Drijfhout
  • Prame derived peptides and immunogenic compositions comprising these
    Publication number: 20140348862
    Abstract: The invention relates to a peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein and to its use as such or in a composition as a medicament for the treatment and/or prevention of cancer.
    Type: Application
    Filed: July 18, 2013
    Publication date: November 27, 2014
    Applicant: Academisch Ziekenhuis Leiden h.o.d.n. LUMC
    Inventors: Jan Kessler, Marieke Griffioen, Cornelis Johannes Maria Melief, Jan Wouter Drijfhout
  • METHOD OF DETECTING AUTO-ANTIBODIES FROM PATIENTS SUFFERING FROM RHEUMATOID ARTHRITIS, A PEPTIDE AND AN ASSAY KIT
    Publication number: 20140336069
    Abstract: Peptides useful in determining the presence of autoantibodies in patients suffering from rheumatoid arthritis are disclosed.
    Type: Application
    Filed: May 23, 2014
    Publication date: November 13, 2014
    Applicant: STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN
    Inventors: Waltherus Jacobus Wilhelmus VAN VENROOIJ, Jan Wouter DRIJFHOUT, Martinus Adrianus Maria VAN BOEKEL, Gerardus Jozef Maria PRUIJN