Patents by Inventor Jan Zielinski
Jan Zielinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10918613Abstract: One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an oral disease, caused by a dental device in the mouth of a patient. Another embodiment relates to a method of preventing, reducing, or eliminating at least one negative effect of inflammation. The method may include applying topically to a soft oral tissue in the patient an oral antioxidant composition. The antioxidant composition may include between 0.0001% and 5.0% w/w or at least one antioxidant, wherein the at least one antioxidant includes a natural phytochemcial antioxidant, a flavonoid, an anthocyanidin, a dihydrochalcone, a phenylpropanoid, a chalcone, a curcuminoid, a tannin, a stilbenoid, a coumarin, a carotenoid, or a vitamin, and an orally pharmaceutically acceptable carrier. The pH of the oral antioxidant composition may be at least 5.0.Type: GrantFiled: July 28, 2016Date of Patent: February 16, 2021Assignee: Perio Sciences, LLCInventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
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Publication number: 20160331707Abstract: One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an oral disease, caused by a dental device in the mouth of a patient. Another embodiment relates to a method of preventing, reducing, or eliminating at least one negative effect of inflammation. The method may include applying topically to a soft oral tissue in the patient an oral antioxidant composition. The antioxidant composition may include between 0.0001% and 5.0% w/w or at least one antioxidant, wherein the at least one antioxidant includes a natural phytochemcial antioxidant, a flavonoid, an anthocyanidin, a dihydrochalcone, a phenylpropanoid, a chalcone, a curcuminoid, a tannin, a stilbenoid, a coumarin, a carotenoid, or a vitamin, and an orally pharmaceutically acceptable carrier. The pH of the oral antioxidant composition may be at least 5.0.Type: ApplicationFiled: July 28, 2016Publication date: November 17, 2016Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
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Patent number: 9421180Abstract: One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an oral disease, caused by a dental device in the mouth of a patient. Another embodiment relates to a method of preventing, reducing, or eliminating at least one negative effect of inflammation. The method may include applying topically to a soft oral tissue in the patient an oral antioxidant composition. The antioxidant composition may include between 0.0001% and 5.0% w/w or at least one antioxidant, wherein the at least one antioxidant includes a natural phytochemcial antioxidant, a flavonoid, an anthocyanidin, a dihydrochalcone, a phenylpropanoid, a chalcone, a curcuminoid, a tannin, a stilbenoid, a coumarin, a carotenoid, or a vitamin, and an orally pharmaceutically acceptable carrier. The pH of the oral antioxidant composition may be at least 5.0.Type: GrantFiled: September 28, 2012Date of Patent: August 23, 2016Assignee: Perio Sciences, LLCInventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
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Patent number: 9248082Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.Type: GrantFiled: April 15, 2009Date of Patent: February 2, 2016Assignee: L'OREALInventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
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Publication number: 20150374652Abstract: One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrcurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrcurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.Type: ApplicationFiled: September 3, 2015Publication date: December 31, 2015Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
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Publication number: 20140378547Abstract: One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an oral disease, caused by a dental device in the mouth of a patient. Another embodiment relates to a method of preventing, reducing, or eliminating at least one negative effect of inflammation. The method may include applying topically to a soft oral tissue in the patient an oral antioxidant composition. The antioxidant composition may include between 0.0001% and 5.0% w/w or at least one antioxidant, wherein the at least one antioxidant includes a natural phytochemcial antioxidant, a flavonoid, an anthocyanidin, a dihydrochalcone, a phenylpropanoid, a chalcone, a curcuminoid, a tannin, a stilbenoid, a coumarin, a carotenoid, or a vitamin, and an orally pharmaceutically acceptable carrier. The pH of the oral antioxidant composition may be at least 5.0.Type: ApplicationFiled: September 28, 2012Publication date: December 25, 2014Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
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Publication number: 20140050675Abstract: One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrcurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrcurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.Type: ApplicationFiled: October 23, 2013Publication date: February 20, 2014Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
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Publication number: 20140033631Abstract: A panel element (2) for use in constructing a shelter is disclosed. The panel element comprises a body portion (4), first locking means (8) mounted to the body portion, and second locking means (6) mounted to the body portion. The first locking means comprises an elongate member (10) having a plurality of apertures (8) therein, and the second locking means comprises a plurality of locking elements (6) moveable relative to the body portion between a storage position and a deployed position. In the deployed position, the locking elements engage respective apertures of a first locking means of a further panel element to urge the further panel element towards the first panel element.Type: ApplicationFiled: February 10, 2012Publication date: February 6, 2014Inventors: Michael Jon Rokk, Garry Jan Zielinski, Michael Jon Albans-Jackson
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Publication number: 20110077275Abstract: One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrcurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrcurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.Type: ApplicationFiled: July 27, 2010Publication date: March 31, 2011Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
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Publication number: 20100183524Abstract: One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrocurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrocurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.Type: ApplicationFiled: November 20, 2009Publication date: July 22, 2010Applicant: Perio Sciences, LLCInventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
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Publication number: 20090286874Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.Type: ApplicationFiled: April 15, 2009Publication date: November 19, 2009Applicant: L'OREALInventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
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Publication number: 20070225360Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.Type: ApplicationFiled: March 20, 2007Publication date: September 27, 2007Applicant: L'OREALInventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
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Publication number: 20060251592Abstract: Isoflavones are modified by esterification at one or more of the C4?, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hydrolysable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs. Further preferred uses include incorporation of contemplated compounds into topical formulations, and especially cosmetic topical formulations.Type: ApplicationFiled: February 18, 2004Publication date: November 9, 2006Inventors: Sheldon Hendler, Jan Zielinski
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Patent number: 6958156Abstract: Isoflavones are modified by esterification at one or more of the C4?, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hydrolysable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs. Further preferred uses include incorporation of contemplated compounds into topical formulations, and especially cosmetic topical formulations.Type: GrantFiled: February 20, 2003Date of Patent: October 25, 2005Assignee: Vyrex CorporationInventors: Sheldon S. Hendler, Jan Zielinski
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Publication number: 20050154054Abstract: The present invention relates to ascorbic acid single-phase solution compositions that provide enhanced stability, enhanced solubility and an enhanced photoprotective effect as compared to prior compositions. The compositions comprise L-ascorbic acid; a cinnamic acid derivative such as p-coumaric acid, ferulic acid, caffeic acid, sinapinic acid, a derivative thereof, and a combination thereof; a solvent comprising a glycol ether and an alkanediol; and water; the composition having a pH of no more than about 3.5. The compositions may also comprise a form of Vitamin E and are useful for treatment of radical-induced damage to a subject, particularly the skin of a subject.Type: ApplicationFiled: January 11, 2005Publication date: July 14, 2005Applicant: SkinCeuticals, Inc.Inventors: Jan Zielinski, Sheldon Pinnell
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Publication number: 20040224004Abstract: Methods and compositions are directed towards a product comprising a food serving that includes at least one of silymarin, an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, and glucuronic acid in an amount effective to reduce volatile sulfur compounds in breath of an individual at least 10% when the food serving is administered to the individual. Preferred food servings are packaged to form a standard serving size. Thus, particularly contemplated methods comprise a step in which a standard serving size is identified. In a further step, at least one ingredient selected from the group consisting of silymarin, an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, and glucuronic acid is included in the serving size, and in a still further step, the product is advertised as a treatment of bad breath.Type: ApplicationFiled: June 20, 2003Publication date: November 11, 2004Inventor: Jan Zielinski
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Publication number: 20030212009Abstract: Isoflavones are modified by esterification at one or more of the C4′, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hydrolysable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs. Further preferred uses include incorporation of contemplated compounds into topical formulations, and especially cosmetic topical formulations.Type: ApplicationFiled: February 20, 2003Publication date: November 13, 2003Inventors: Sheldon S. Hendler, Jan Zielinski
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Publication number: 20030124230Abstract: A food product includes at least silymarin, betaine, or a combination thereof, and one of an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, or glucuronic acid in an amount effective to significantly reduce bad breath. Especially preferred food products include significant quantities of silymarin and betaine. The food product is advantageously advertised as reducing bad breath, improving liver function, digestion, and/or periodontal health. Contemplated food products include animal treats, and especially dog biscuits or other treats.Type: ApplicationFiled: December 4, 2002Publication date: July 3, 2003Inventor: Jan Zielinski
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Patent number: 6541613Abstract: Isoflavones are modified by esterification at one or more of the C4′, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hyrolyzable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs.Type: GrantFiled: December 15, 2000Date of Patent: April 1, 2003Assignee: Uyrex CorporationInventors: Sheldon S. Hendler, Jan Zielinski
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Publication number: 20020111466Abstract: Isoflavones are modified by esterification at one or more of the C4′, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hyrolyzable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs.Type: ApplicationFiled: December 15, 2000Publication date: August 15, 2002Inventors: Sheldon S. Hendler, Jan Zielinski