Patents by Inventor Jan Zielinski

Jan Zielinski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10918613
    Abstract: One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an oral disease, caused by a dental device in the mouth of a patient. Another embodiment relates to a method of preventing, reducing, or eliminating at least one negative effect of inflammation. The method may include applying topically to a soft oral tissue in the patient an oral antioxidant composition. The antioxidant composition may include between 0.0001% and 5.0% w/w or at least one antioxidant, wherein the at least one antioxidant includes a natural phytochemcial antioxidant, a flavonoid, an anthocyanidin, a dihydrochalcone, a phenylpropanoid, a chalcone, a curcuminoid, a tannin, a stilbenoid, a coumarin, a carotenoid, or a vitamin, and an orally pharmaceutically acceptable carrier. The pH of the oral antioxidant composition may be at least 5.0.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: February 16, 2021
    Assignee: Perio Sciences, LLC
    Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
  • Publication number: 20160331707
    Abstract: One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an oral disease, caused by a dental device in the mouth of a patient. Another embodiment relates to a method of preventing, reducing, or eliminating at least one negative effect of inflammation. The method may include applying topically to a soft oral tissue in the patient an oral antioxidant composition. The antioxidant composition may include between 0.0001% and 5.0% w/w or at least one antioxidant, wherein the at least one antioxidant includes a natural phytochemcial antioxidant, a flavonoid, an anthocyanidin, a dihydrochalcone, a phenylpropanoid, a chalcone, a curcuminoid, a tannin, a stilbenoid, a coumarin, a carotenoid, or a vitamin, and an orally pharmaceutically acceptable carrier. The pH of the oral antioxidant composition may be at least 5.0.
    Type: Application
    Filed: July 28, 2016
    Publication date: November 17, 2016
    Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
  • Patent number: 9421180
    Abstract: One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an oral disease, caused by a dental device in the mouth of a patient. Another embodiment relates to a method of preventing, reducing, or eliminating at least one negative effect of inflammation. The method may include applying topically to a soft oral tissue in the patient an oral antioxidant composition. The antioxidant composition may include between 0.0001% and 5.0% w/w or at least one antioxidant, wherein the at least one antioxidant includes a natural phytochemcial antioxidant, a flavonoid, an anthocyanidin, a dihydrochalcone, a phenylpropanoid, a chalcone, a curcuminoid, a tannin, a stilbenoid, a coumarin, a carotenoid, or a vitamin, and an orally pharmaceutically acceptable carrier. The pH of the oral antioxidant composition may be at least 5.0.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: August 23, 2016
    Assignee: Perio Sciences, LLC
    Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
  • Patent number: 9248082
    Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: February 2, 2016
    Assignee: L'OREAL
    Inventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
  • Publication number: 20150374652
    Abstract: One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrcurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrcurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.
    Type: Application
    Filed: September 3, 2015
    Publication date: December 31, 2015
    Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
  • Publication number: 20140378547
    Abstract: One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an oral disease, caused by a dental device in the mouth of a patient. Another embodiment relates to a method of preventing, reducing, or eliminating at least one negative effect of inflammation. The method may include applying topically to a soft oral tissue in the patient an oral antioxidant composition. The antioxidant composition may include between 0.0001% and 5.0% w/w or at least one antioxidant, wherein the at least one antioxidant includes a natural phytochemcial antioxidant, a flavonoid, an anthocyanidin, a dihydrochalcone, a phenylpropanoid, a chalcone, a curcuminoid, a tannin, a stilbenoid, a coumarin, a carotenoid, or a vitamin, and an orally pharmaceutically acceptable carrier. The pH of the oral antioxidant composition may be at least 5.0.
    Type: Application
    Filed: September 28, 2012
    Publication date: December 25, 2014
    Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
  • Publication number: 20140050675
    Abstract: One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrcurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrcurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.
    Type: Application
    Filed: October 23, 2013
    Publication date: February 20, 2014
    Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
  • Publication number: 20140033631
    Abstract: A panel element (2) for use in constructing a shelter is disclosed. The panel element comprises a body portion (4), first locking means (8) mounted to the body portion, and second locking means (6) mounted to the body portion. The first locking means comprises an elongate member (10) having a plurality of apertures (8) therein, and the second locking means comprises a plurality of locking elements (6) moveable relative to the body portion between a storage position and a deployed position. In the deployed position, the locking elements engage respective apertures of a first locking means of a further panel element to urge the further panel element towards the first panel element.
    Type: Application
    Filed: February 10, 2012
    Publication date: February 6, 2014
    Inventors: Michael Jon Rokk, Garry Jan Zielinski, Michael Jon Albans-Jackson
  • Publication number: 20110077275
    Abstract: One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrcurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrcurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.
    Type: Application
    Filed: July 27, 2010
    Publication date: March 31, 2011
    Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
  • Publication number: 20100183524
    Abstract: One embodiment of the invention is directed to an oral antioxidant composition including between 0.0001% and 5.0% w/w antioxidant, wherein the antioxidant includes cinnamic acid derivative, tetrahydrocurcuminoids, or phloretin and an orally pharmaceutically acceptable carrier. The composition may have a pH of at least 5.0. According to still further embodiments, the composition may also include between 0.0001% and 5.0% w/w of one or two more additional antioxidants that include cinnamic acid derivative, tetrahydrocurcuminoids, phloretin, or a stilbene derivative. In more particular embodiments, the cinnamic acid derivative may include trans-ferulic acid, the tetrahydrocurcuminoids may include tetrahydrocurcuminoids CG™, or the stilbene derivative may include resveratrol. Other embodiments may relate to methods of treating or preventing an oral disease by applying topically an antioxidant composition as described above.
    Type: Application
    Filed: November 20, 2009
    Publication date: July 22, 2010
    Applicant: Perio Sciences, LLC
    Inventors: Jan Zielinski, Thomas Russell Moon, Edward P. Allen
  • Publication number: 20090286874
    Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.
    Type: Application
    Filed: April 15, 2009
    Publication date: November 19, 2009
    Applicant: L'OREAL
    Inventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
  • Publication number: 20070225360
    Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.
    Type: Application
    Filed: March 20, 2007
    Publication date: September 27, 2007
    Applicant: L'OREAL
    Inventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
  • Publication number: 20060251592
    Abstract: Isoflavones are modified by esterification at one or more of the C4?, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hydrolysable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs. Further preferred uses include incorporation of contemplated compounds into topical formulations, and especially cosmetic topical formulations.
    Type: Application
    Filed: February 18, 2004
    Publication date: November 9, 2006
    Inventors: Sheldon Hendler, Jan Zielinski
  • Patent number: 6958156
    Abstract: Isoflavones are modified by esterification at one or more of the C4?, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hydrolysable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs. Further preferred uses include incorporation of contemplated compounds into topical formulations, and especially cosmetic topical formulations.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: October 25, 2005
    Assignee: Vyrex Corporation
    Inventors: Sheldon S. Hendler, Jan Zielinski
  • Publication number: 20050154054
    Abstract: The present invention relates to ascorbic acid single-phase solution compositions that provide enhanced stability, enhanced solubility and an enhanced photoprotective effect as compared to prior compositions. The compositions comprise L-ascorbic acid; a cinnamic acid derivative such as p-coumaric acid, ferulic acid, caffeic acid, sinapinic acid, a derivative thereof, and a combination thereof; a solvent comprising a glycol ether and an alkanediol; and water; the composition having a pH of no more than about 3.5. The compositions may also comprise a form of Vitamin E and are useful for treatment of radical-induced damage to a subject, particularly the skin of a subject.
    Type: Application
    Filed: January 11, 2005
    Publication date: July 14, 2005
    Applicant: SkinCeuticals, Inc.
    Inventors: Jan Zielinski, Sheldon Pinnell
  • Publication number: 20040224004
    Abstract: Methods and compositions are directed towards a product comprising a food serving that includes at least one of silymarin, an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, and glucuronic acid in an amount effective to reduce volatile sulfur compounds in breath of an individual at least 10% when the food serving is administered to the individual. Preferred food servings are packaged to form a standard serving size. Thus, particularly contemplated methods comprise a step in which a standard serving size is identified. In a further step, at least one ingredient selected from the group consisting of silymarin, an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, and glucuronic acid is included in the serving size, and in a still further step, the product is advertised as a treatment of bad breath.
    Type: Application
    Filed: June 20, 2003
    Publication date: November 11, 2004
    Inventor: Jan Zielinski
  • Publication number: 20030212009
    Abstract: Isoflavones are modified by esterification at one or more of the C4′, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hydrolysable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs. Further preferred uses include incorporation of contemplated compounds into topical formulations, and especially cosmetic topical formulations.
    Type: Application
    Filed: February 20, 2003
    Publication date: November 13, 2003
    Inventors: Sheldon S. Hendler, Jan Zielinski
  • Publication number: 20030124230
    Abstract: A food product includes at least silymarin, betaine, or a combination thereof, and one of an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, or glucuronic acid in an amount effective to significantly reduce bad breath. Especially preferred food products include significant quantities of silymarin and betaine. The food product is advantageously advertised as reducing bad breath, improving liver function, digestion, and/or periodontal health. Contemplated food products include animal treats, and especially dog biscuits or other treats.
    Type: Application
    Filed: December 4, 2002
    Publication date: July 3, 2003
    Inventor: Jan Zielinski
  • Patent number: 6541613
    Abstract: Isoflavones are modified by esterification at one or more of the C4′, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hyrolyzable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: April 1, 2003
    Assignee: Uyrex Corporation
    Inventors: Sheldon S. Hendler, Jan Zielinski
  • Publication number: 20020111466
    Abstract: Isoflavones are modified by esterification at one or more of the C4′, C5, C6, and C7 positions to promote bioavailability, and especially to enhance solubility over the corresponding unesterified isoflavones. Preferred modifications produce a carboxylic acid hemiester or a phosphate ester which is biologically hyrolyzable. Preferred starting isoflavones are genistin and daidzin, and still more preferably comprises an aglycone form such as genistein or daidzein. Esterified isoflavones may be employed therapeutically or prophylactically for a variety of conditions, provided as a dietary supplement, or added to natural or processed food-stuffs.
    Type: Application
    Filed: December 15, 2000
    Publication date: August 15, 2002
    Inventors: Sheldon S. Hendler, Jan Zielinski