Patents by Inventor Jana MINARIKOVÁ

Jana MINARIKOVÁ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNAI INDUCED HUNTINGTIN GENE SUPPRESSION
    Publication number: 20230119344
    Abstract: The present invention provides for a double stranded RNA comprising a first RNA sequence and a second RNA sequence wherein the first and second RNA sequence are substantially complementary, wherein the first RNA sequence has a sequence length of at least 19 nucleotides and is substantially complementary to SEQ ID NO. 1. Said double stranded RNA is for use in inducing RNAi against Huntingtin exon 1 sequences. The double stranded RNA of to the invention was capable of reducing neuronal cell death and huntingtin aggregates in an animal model.
    Type: Application
    Filed: May 24, 2022
    Publication date: April 20, 2023
    Applicant: Uniqure IP B.V.
    Inventors: Pavlina Stefanova KONSTANTINOVA, Jana MINARIKOVÁ