Patents by Inventor Jana Pätz
Jana Pätz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10864164Abstract: The invention relates to a tamper-resistant tablet comprising (i) a matrix material in an amount of more than one third of the total weight of the tablet; and (ii) a plurality of coated particulates in an amount of less than two thirds of the total weight of the tablet; wherein said particulates comprise a pharmacologically active compound and a physiologically acceptable polymer, preferably a polyalkylene oxide; and form a discontinuous phase within the matrix material; which preferably provides under in vitro conditions immediate release of the pharmacologically active compound in accordance with Ph. Eur.; and method of using said tablet to treat pain and other conditions.Type: GrantFiled: December 19, 2018Date of Patent: December 15, 2020Assignee: Grünenthal GmbHInventors: Sebastian Schwier, Marcel Haupts, Lutz Barnscheid, Jana Pätz
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Publication number: 20190142757Abstract: The invention relates to a tamper-resistant pharmaceutical dosage form comprising one or more particles, wherein each of said one or more particles comprises a pharmacologically active ingredient and a physiologically acceptable polymer; has a breaking strength of at least 300 N; has a weight of at least 2 mg; and optionally, comprises a film-coating; wherein the total weight of the pharmaceutical dosage form is greater than the total weight of said one or more particles.Type: ApplicationFiled: November 9, 2018Publication date: May 16, 2019Applicant: GRÜNENTHAL GMBHInventors: LUTZ BARNSCHEID, ANJA GEIßLER, KLAUS WENING, JANA PÄTZ
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Publication number: 20190125680Abstract: The invention relates to a tamper-resistant tablet comprising (i) a matrix material in an amount of more than one third of the total weight of the tablet; and (ii) a plurality of coated particulates in an amount of less than two thirds of the total weight of the tablet; wherein said particulates comprise a pharmacologically active compound and a physiologically acceptable polymer, preferably a polyalkylene oxide; and form a discontinuous phase within the matrix material; which preferably provides under in vitro conditions immediate release of the pharmacologically active compound in accordance with Ph. Eur.; and method of using said tablet to treat pain and other conditions.Type: ApplicationFiled: December 19, 2018Publication date: May 2, 2019Applicant: Grünenthal GmbHInventors: Sebastian SCHWIER, Marcel HAUPTS, Lutz BARNSCHEID, Jana PÄTZ
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Patent number: 10201502Abstract: The invention relates to a tamper-resistant tablet comprising (i) a matrix material in an amount of more than one third of the total weight of the tablet; and (ii) a plurality of coated particulates in an amount of less than two thirds of the total weight of the tablet; wherein said particulates comprise a pharmacologically active compound and a physiologically acceptable polymer, preferably a polyalkylene oxide; and form a discontinuous phase within the matrix material; which preferably provides under in vitro conditions immediate release of the pharmacologically active compound in accordance with Ph. Eur.; and method of using said tablet to treat pain and other conditions.Type: GrantFiled: July 27, 2012Date of Patent: February 12, 2019Assignee: GRUENENTHAL GMBHInventors: Sebastian Schwier, Marcel Haupts, Lutz Barnscheid, Jana Pätz
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Patent number: 10154966Abstract: The invention relates to a tamper-resistant pharmaceutical dosage form comprising one or more particles, wherein each of said one or more particles comprises a pharmacologically active ingredient and a physiologically acceptable polymer; has a breaking strength of at least 300 N; has a weight of at least 2 mg; and optionally, comprises a film-coating; wherein the total weight of the pharmaceutical dosage form is greater than the total weight of said one or more particles.Type: GrantFiled: May 27, 2014Date of Patent: December 18, 2018Assignee: GRÜNENTHAL GMBHInventors: Lutz Barnscheid, Anja Geiβler, Klaus Wening, Jana Pätz
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Publication number: 20180326067Abstract: A thermoformed, tamper-resistant pharmaceutical dosage form comprises: a) a pharmacologically active ingredient; b) a polyalkylene oxide having a weight average molecular weight of more than 200,000 g/mol; and c) a zinc component, wherein the content of said zinc component is at least 1 ppm, relative to the total weight of the pharmaceutical dosage form. When the pharmacologically active ingredient is effective against pain, the pharmaceutical dosage form may be used in a method of treating pain. When the pharmacologically active ingredient has abuse potential, the pharmaceutical dosage form may be used in a method of reducing the incidence of the abuse of said pharmacologically active ingredient.Type: ApplicationFiled: July 20, 2018Publication date: November 15, 2018Applicant: GRÜNENTHAL GMBHInventors: LUTZ BARNSCHEID, ERIC GALIA, ANJA GEIßLER, JANA PÄTZ, SEBASTIAN SCHWIER, JULIA BARONSKY-PROBST
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Patent number: 10064945Abstract: A thermoformed, tamper-resistant pharmaceutical dosage form comprises: a) a pharmacologically active ingredient; b) a polyalkylene oxide having a weight average molecular weight of more than 200,000 g/mol; and c) a zinc component, wherein the content of said zinc component is at least 1 ppm, relative to the total weight of the pharmaceutical dosage form. When the pharmacologically active ingredient is effective against pain, the pharmaceutical dosage form may be used in a method of treating pain. When the pharmacologically active ingredient has abuse potential, the pharmaceutical dosage form may be used in a method of reducing the incidence of the abuse of said pharmacologically active ingredient.Type: GrantFiled: May 10, 2013Date of Patent: September 4, 2018Assignee: GRUENENTHAL GMBHInventors: Lutz Barnscheid, Eric Galia, Anja Geißler, Jana Pätz, Sebastian Schwier, Julia Baronsky-Probst
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Publication number: 20180221307Abstract: The invention relates to a monolithic pharmaceutical dosage form comprising a hot melt-extruded first segment (S1) and a second segment (S2); wherein the first segment (S1) contains at least a first pharmacologically active ingredient (A1) and/or the second segment (S2) contains at least a second pharmacologically active ingredient (A2); and the segment (S1) and/or the segment (S2) is tamper-resistant and/or exhibits a breaking strength of at least 300 N.Type: ApplicationFiled: January 30, 2018Publication date: August 9, 2018Applicant: GRÜNENTHAL GMBHInventors: ANJA GEIßLER-FICHTNER, Klaus Wening, Lutz Barnscheid, Jana Pätz
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Patent number: 9872835Abstract: The invention relates to an oral pharmaceutical dosage form providing resistance against dose dumping in aqueous ethanol and comprising a pharmacologically active ingredient embedded in a matrix material, wherein the matrix material comprises an alkyl cellulose and a heteropolysaccharide; and wherein the relative weight ratio of heteropolysaccharide to alkyl cellulose is within the range of from 1:20 to 20:1; and wherein the total content of alkyl cellulose and heteropolysaccharide is at least 35 wt.-%, relative to the total weight of the dosage form. A process of producing the dosage form and methods of using the dosage form, for example to treat pain, are also disclosed.Type: GrantFiled: May 22, 2015Date of Patent: January 23, 2018Assignee: GRÜNENTHAL GMBHInventors: Lutz Barnscheid, Klaus Wening, Jana Pätz, Anja Geissler
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Publication number: 20170296472Abstract: The invention relates to a pharmaceutical dosage form comprising (i) at least one formed segment (S1), which contains a first pharmacologically active ingredient (A1) and provides prolonged release thereof, and (ii) at least one further segment (S2), which contains a second pharmacologically active ingredient (A2) and provides immediate release thereof, wherein the at least one formed segment (S1) exhibits a higher breaking strength than the at least one further segment (S2) and the at least one formed segment (S1) exhibits a breaking strength of more than 500 N.Type: ApplicationFiled: June 29, 2017Publication date: October 19, 2017Applicant: GRÜNENTHAL GMBHInventors: Lutz BARNSCHEID, Anja Geissler, Klaus Wening, Stefanie Strauch, Jana Pätz, Sebastian Schwier
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Patent number: 9737490Abstract: The invention relates to a pharmaceutical dosage form comprising (i) at least one formed segment (S1), which contains a first pharmacologically active ingredient (A1) and provides prolonged release thereof, and (ii) at least one further segment (S2), which contains a second pharmacologically active ingredient (A2) and provides immediate release thereof, wherein the at least one formed segment (S1) exhibits a higher breaking strength than the at least one further segment (S2) and the at least one formed segment (S1) exhibits a breaking strength of more than 500 N.Type: GrantFiled: May 27, 2014Date of Patent: August 22, 2017Assignee: GRÜNENTHAL GMBHInventors: Lutz Barnscheid, Anja Geiβler, Klaus Wening, Stefanie Strauch, Jana Pätz, Sebastian Schwier
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Publication number: 20160338976Abstract: Summary: The invention relates to a monolithic pharmaceutical dosage form comprising a hot melt-extruded first segment (S1) and a second segment (S2); wherein the first segment (S1) contains at least a first pharmacologically active ingredient (A1) and/or the second segment (S2) contains at least a second pharmacologically active ingredient (A2); and the segment (S1) and/or the segment (S2) is tamper-resistant and/or exhibits a breaking strength of at least 300 N.Type: ApplicationFiled: August 5, 2016Publication date: November 24, 2016Applicant: GRÜNENTHAL GMBHInventors: ANJA GEIßLER, KLAUS WENING, LUTZ BARNSCHEID, JANA PÄTZ
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Patent number: 9403842Abstract: The present invention relates to prasugrel or a pharmaceutically compatible salt thereof, compositions that contain this active substance and pharmaceutical compositions that contain this active substance or a composition containing this active substance. The present invention further relates to methods for producing the novel compositions.Type: GrantFiled: August 4, 2010Date of Patent: August 2, 2016Assignee: ratiopharm GmbHInventors: Sandra Brueck, Jana Paetz
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Publication number: 20160199306Abstract: The invention relates to a tamper-resistant tablet comprising (i) a matrix material in an amount of more than one third of the total weight of the tablet; and (ii) a plurality of particulates in an amount of less than two thirds of the total weight of the tablet; wherein said particulates comprise a pharmacologically active compound and a polyalkylene oxide; and form a discontinuous phase within the matrix material; and method of using said tablet to treat pain and other conditions.Type: ApplicationFiled: March 18, 2016Publication date: July 14, 2016Applicant: Grünenthal GmbHInventors: Sebastian Schwier, Marcel Haupts, Udo Rüttgers, Lutz Barnscheid, Jana Pätz
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Publication number: 20150335592Abstract: The invention relates to an oral pharmaceutical dosage form providing resistance against dose dumping in aqueous ethanol and comprising a pharmacologically active ingredient embedded in a matrix material, wherein the matrix material comprises an alkyl cellulose and a heteropolysaccharide; and wherein the relative weight ratio of heteropolysaccharide to alkyl cellulose is within the range of from 1:20 to 20:1; and wherein the total content of alkyl cellulose and heteropolysaccharide is at least 35 wt.-%, relative to the total weight of the dosage form. A process of producing the dosage form and methods of using the dosage form, for example to treat pain, are also disclosed.Type: ApplicationFiled: May 22, 2015Publication date: November 26, 2015Applicant: GRÜNENTHAL GMBHInventors: LUTZ BARNSCHEID, KLAUS WENING, JANA PÄTZ, ANJA GEISSLER
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Patent number: 9085507Abstract: The invention concerns desfesoterodine in the form of a tartaric acid salt, in particular in the polymorphic “R form”, as well as a process for its production. In a second aspect, the invention concerns the desfesoterodine of the invention in a microencapsulated form.Type: GrantFiled: May 10, 2010Date of Patent: July 21, 2015Assignee: ratiopharm GmbHInventors: Dirk Fischer, Gertraud Koellner, Gertrud Auer, Katrin Rimkus, Frank Muskulus, Sandra Brueck, Jana Paetz
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Publication number: 20150164807Abstract: The invention relates to a monolithic pharmaceutical dosage form comprising a hot melt-extruded first segment (S1) and a second segment (S2); wherein the first segment (S1) contains at least a first pharmacologically active ingredient (A1) and/or the second segment (S2) contains at least a second pharmacologically active ingredient (A2); and the segment (S1) and/or the segment (S2) is tamper-resistant and/or exhibits a breaking strength of at least 300 N.Type: ApplicationFiled: December 15, 2014Publication date: June 18, 2015Applicant: GRÜNENTHAL GMBHInventors: ANJA GEISSLER, KLAUS WENING, LUTZ BARNSCHEID, JANA PÄTZ
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Patent number: 8940757Abstract: The present invention relates to Prasugrel or a pharmaceutically acceptable salt thereof, compositions containing said active ingredient as well as pharmaceutical compositions containing said active ingredient or a composition containing said active ingredient. The present invention further relates to methods for the preparation of the novel compositions.Type: GrantFiled: February 10, 2011Date of Patent: January 27, 2015Assignee: ratiopharm GmbHInventors: Sandra Brueck, Jana Paetz
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Publication number: 20140356428Abstract: The invention relates to a pharmaceutical dosage form comprising (i) at least one formed segment (S1), which contains a first pharmacologically active ingredient (A1) and provides prolonged release thereof, and (ii) at least one further segment (S2), which contains a second pharmacologically active ingredient (A2) and provides immediate release thereof, wherein the at least one formed segment (S1) exhibits a higher breaking strength than the at least one further segment (S2) and the at least one formed segment (S1) exhibits a breaking strength of more than 500 N.Type: ApplicationFiled: May 27, 2014Publication date: December 4, 2014Applicant: GRÜNENTHAL GMBHInventors: LUTZ BARNSCHEID, ANJA GEIßLER, KLAUS WENING, STEFANIE STRAUCH, JANA PÄTZ, SEBASTIAN SCHWIER
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Publication number: 20140356426Abstract: The invention relates to a tamper-resistant pharmaceutical dosage form comprising one or more particles, wherein each of said one or more particles comprises a pharmacologically active ingredient and a physiologically acceptable polymer; has a breaking strength of at least 300 N; has a weight of at least 2 mg; and optionally, comprises a film-coating; wherein the total weight of the pharmaceutical dosage form is greater than the total weight of said one or more particles.Type: ApplicationFiled: May 27, 2014Publication date: December 4, 2014Applicant: GRÜNENTHAL GMBHInventors: LUTZ BARNSCHEID, ANJA GEIßLER, KLAUS WENING, JANA PÄTZ