Patents by Inventor Janardan Singh

Janardan Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9018226
    Abstract: The present invention relates to bioactive extracts its fractions and isolation of compound from Rauwolfia tetraphylla. The extracts and fractions are useful for the treatment of psychosis based on in-vivo validation on animal model and proportional binding affinities for dopaminergic-D2, Cholinergic (muscarinic) and Serotonergic (5HT2A) receptors for antipsychotic activity. The present invention relates to novel antipsychotic activity in the leaf alkaloids of Formula 1 and 2 named tetrahydroalstonine, 10-methoxytetrahydroalstonine, isoreserpiline, 10-demethoxyreserpiline, 11-demethoxyreserpiline, reserpiline and ?-yohimbine. The present invention also relates to processes for obtaining antipsychotic extracts as well as for the isolation of alkaloids of formula 1 and 2 from the leaves of Rauwolfia tetraphylla. The present invention particularly relates to significant antipsychotic activity in the MeOH extract, ethylacetate and chloroform fractions of R.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: April 28, 2015
    Assignee: Council of Scientific & Industrial Research
    Inventors: Santosh Kumar Srivastava, Ashok Kumar Agrawal, Subhash Chandra Singh, Vinay Kumar Khanna, Janardan Singh, Chandeshwar Nath, Madan Mohan Gupta, Shikha Gupta, Ram Kishor Verma, Anirban Pal, Dnyaneshwar Umrao Bawankule, Dharmendra Saikia, Anil Kumar Gupta, Anupam Maurya, Suman Preet Singh Khanuja
  • Publication number: 20120184576
    Abstract: The present invention relates to bioactive extracts its fractions and isolation of compound from Rauwolfia tetraphylla. The extracts and fractions are useful for the treatment of psychosis based on in-vivo validation on animal model and proportional binding affinities for dopaminergic-D2, Cholinergic (muscarinic) and Serotonergic (5HT2A) receptors for antipsychotic activity. The present invention relates to novel antipsychotic activity in the leaf alkaloids of Formula 1 and 2 named tetrahydroalstonine, 10-methoxytetrahydroalstonine, isoreserpiline, 10-der?ethoxyreserpiline, 11-demethoxyreserpiline, reserpiline and ?-yohimbine. The present invention also relates to processes for obtaining antipsychotic extracts as well as for the isolation of alkabids of formula 1 and 2 from the leaves of Rauwolfia tetraphylla. The present invention particularly relates to significant antipsychotic activity in the MeOH extract, ethylacetate and chloroform fractions of R.
    Type: Application
    Filed: March 31, 2010
    Publication date: July 19, 2012
    Inventors: Santosh Kumar Srivastava, Ashok Kumar Agrawal, Subhash Chandra Singh, Vinay Kumar Khanna, Janardan Singh, Chandeshwar Nath, Madan Mohan Gupta, Shikha Gupta, Ram Kishor Verma, Anirban Pal, Duyaneshwar Umrao Bawankule, Dharmendra Saikia, Anil Kumar Gupta, Anupam Maurya, Suman Preet Singh Khanuja
  • Patent number: 6517861
    Abstract: An herbal dietary supplement composition for lactating mothers, comprising the required quantum of one or more herbs selected from Groups A to D, wherein the herbs from Group A being comprised of medicinal plant materials having galactagogue properties, Group B being comprised of medicinal plant materials having adaptogenic and anti-stress properties, Group C being comprised medicinal plant materials having hepatoprotective properties and Group D being comprised of medicinal plant materials having digestive and appetite improving properties, along with a required quantum of additives selected from nutritive flour and optional frying, flavoring, coloring and dressing agents, and a process for preparing the composition.
    Type: Grant
    Filed: January 22, 2001
    Date of Patent: February 11, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Anil Kumar Singh, Rattan Lal Bindra, Janardan Singh, Sushil Kumar
  • Publication number: 20020136783
    Abstract: An herbal dietary supplement composition for lactating mothers, comprising the required quantum of one or more herbs selected from Groups A to D, wherein the herbs from Group A being comprised of medicinal plant materials having galactagogue properties, Group B being comprised of medicinal plant materials having adaptogenic and anti-stress properties, Group C being comprised medicinal plant materials having hepatoprotective properties and Group D being comprised of medicinal plant materials having digestive and appetite improving properties, along with a required quantum of additives selected from nutritive flour and optional frying, flavoring, coloring and dressing agents, and a process for preparing the composition.
    Type: Application
    Filed: January 22, 2001
    Publication date: September 26, 2002
    Inventors: Anil Kumar Singh, Rattan Lal Bindra, Janardan Singh, Sushil Kumar