Patents by Inventor Janaswamy Madhusudana Rao
Janaswamy Madhusudana Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9642854Abstract: The present invention relates to flavanoid compounds of general formula (X1) wherein: R1 is selected from a group consisting of morpholinyl, N-methyl piperizinyl, piperidinyl and N,N?-dimethylamino groups, and n ranges from 3 to 6, and process for preparation thereof. The present invention relates to the demonstration of anti Helicobacter pylori activity and gastric antisecretory activity of semisynthetically designed flavonoid compounds, to be used for the prevention and treatment of gastroduodenal disorders in general and peptic ulcer diseases in particular. The present invention also relates to a hetero-dimeric bi-functional molecule that can be used as monotherapy substituting/replacing/overcoming currently used triple/quadruple therapy, thereby implicating/anticipating/envisaging its commercial applicability.Type: GrantFiled: February 27, 2015Date of Patent: May 9, 2017Assignee: Council of Scientific & Industrial ResearchInventors: Pratap Kumar Das, Suchandra Goswami, Annalakshmi Chinniah, Janaswamy Madhusudana Rao, Suresh Babu Katragadda
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Publication number: 20150174135Abstract: The present invention relates to flavanoid compounds of general formula (X1) wherein: R1 is selected from a group consisting of morpholinyl, N-methyl piperizinyl, piperidinyl and N,N?-dimethylamino groups, and n ranges from 3 to 6, and process for preparation thereof. The present invention relates to the demonstration of anti Helicobacter pylori activity and gastric antisecretory activity of semisynthetically designed flavonoid compounds, to be used for the prevention and treatment of gastroduodenal disorders in general and peptic ulcer diseases in particular. The present invention also relates to a hetero-dimeric bi-functional molecule that can be used as monotherapy substituting/replacing/overcoming currently used triple/quadruple therapy, thereby implicating/anticipating/envisaging its commercial applicability.Type: ApplicationFiled: February 27, 2015Publication date: June 25, 2015Inventors: Pratap Kumar DAS, Suchandra GOSWAMI, Annalakshmi CHINNIAH, Janaswamy Madhusudana RAO, Suresh Babu KATRAGADDA
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Patent number: 8969384Abstract: The present invention relates to flavanoid compounds of general formula (X1) wherein: R1 is selected from a group consisting of morpholinyl, N-methyl piperizinyl, piperidinyl and N,N?-dimethylamino groups, and n ranges from 3 to 6, and process for preparation thereof. The present invention relates to the demonstration of anti Helicobacter pylori activity and gastric antisecretory activity of semisynthetically designed flavonoid compounds, to be used for the prevention and treatment of gastroduodenal disorders in general and peptic ulcer diseases in particular. The present invention also relates to a hetero-dimeric bi-functional molecule that can be used as monotherapy substituting/replacing/overcoming currently used triple/quadruple therapy, thereby implicating/anticipating/envisaging its commercial applicability.Type: GrantFiled: February 26, 2010Date of Patent: March 3, 2015Assignee: Council of Scientific & Industrial ResearchInventors: Pratap Kumar Das, Suchandra Goswami, Annalakshmi Chinniah, Janaswamy Madhusudana Rao, Suresh Babu Katragadda
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Publication number: 20120277297Abstract: The present invention relates to pharmaceutical composition comprising the naturally occurring compounds selected from (±) Marrnesin, Columbianetin, Dihydroxanthyletin and substituted coumarin derivatives of 7-allyloxy coumarin, 7-benzyloxy coumarin, 7 -methoxycoumarin, 7-acetyloxy coumarin, 4-methyl-7-hydroxy coumarin and 4-methyl-7-acetyloxy coumarin. The said compositions possess a high degree of acetylcholinesterase inhibitory (AChE) property.Type: ApplicationFiled: April 30, 2012Publication date: November 1, 2012Applicant: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Bhimapaka China Raju, Pullela Venkata Srinivas, Katragadda Suresh Babu, Jhillu Singh Yadav, Kondapuram Vijaya Raghvan, Hemant Kumar Singh, Chandiswar Nath
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Patent number: 8188143Abstract: The present invention relates to pharmaceutical composition comprising the naturally occurring compounds selected from (±) Marmesin, Columbianetin, Dihydroxanthyletin and substituted coumarin derivatives of 7-allyloxy coumarin, 7-benzyloxy coumarin, 7-methoxy coumarin, 7-acetyloxy coumarin, 4-methyl-7-hydroxy coumarin and 4-methyl-7-acetyloxy coumarin. The said compositions posses a high degree of acetylcholinesterase inhibitory (AChE) property.Type: GrantFiled: March 20, 2007Date of Patent: May 29, 2012Assignee: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Bhimapaka China Raju, Pullela Venkata Srinivas, Katragadda Suresh Babu, Jhillu Singh Yadav, Kondapuram Vijaya Raghvan, Hemant Kumar Singh, Chandiswar Nath
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Patent number: 7651705Abstract: Provided herein are synergistic herbal compositions for the treatment of gastric ulcer, said composition essentially comprising powdered plant parts of Asparagus racemosus, Glycyrrhiza glabra, Sesamum indicum, Musa sapientum and Trachyspermum roxburghianum and optionally, powdered plant parts of Cyclea peltata, Embelia ribes, Coriandrum sativum Ferulaasafetida, Aloe barbadensis and Evolvulus aisinodes along with one or more pharmaceutically acceptable additives/carriers, processes for preparing such compositions and methods for treating gastric ulcers using such compositions.Type: GrantFiled: October 28, 2003Date of Patent: January 26, 2010Assignee: Council of Scientific & Industrial ResearchInventors: Janaswamy Madhusudana Rao, Upparapalli Sampathkumar, Boggavarapu Subrahmanya Sastry, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan, Gautam Palit, Dwaraka Nath Bhalla, Deepak Rai, Panniyampally Madhavankutty Varier, Trikovil Sankaran Muraleedharan, Kollath Muraleedharan
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Patent number: 7285571Abstract: The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising of (?)-Matairesinol in the range of 9 to 13% by weight, (?)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.Type: GrantFiled: June 17, 2003Date of Patent: October 23, 2007Assignee: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Pullela Venkata Srinivas, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan, Ajit Kumar Saxena, Mutiah Shanmugavel, Himani Kampasi, Gulam Nabi Qazi
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Patent number: 7081260Abstract: The present invention relates to a method for providing ?-glucosidase inhibition to a subject by administering a pharmaceutical composition comprising a ?-glucosidase inhibitory agent selected from pipataline (formula 1a), sesamin (formula 1b), pellitorine (Formula 1c), guineensine (Formula 1d) and brachystamide-B (formula 1e) having therapeutic application for diabetes mellitus, cancer, viral diseases such as hepatitis B and C, HIV, AIDS etc; also the invention provides a process for the isolation of said ?-glucosidase inhibitory agent from the plant source Piper longum in significant yields.Type: GrantFiled: October 29, 2002Date of Patent: July 25, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Pullela Venkata Srinivas, Vummenthala Anuradha, Ashok Kumar Tiwari, Amtul Zehra Ali, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan
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Patent number: 7071341Abstract: The present invention provides novel ?-glucosidase inhibitory compound (?)-mesquitol and its analogs isolated in significant yield from traditional medicinal plant Dichrostachys cinerea and further modification of (?)-mesquitol to enhance the ?-glucosidase inhibitory potential; the invention also identifies the usage of (?)-mesquitol and its analogues, based on their ?-glucosidase inhibitory activity, as broad based potential therapeutics as antihyperglycernic, antidiabatic, antiobesity, antiviral, anticancer, immunestimulants and the like.Type: GrantFiled: April 1, 2003Date of Patent: July 4, 2006Assignee: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Rao Jagadeeshwar Rao, Upparapalli Sampath Kumar, Singireddy Venkat Reddy, Ashok Kumar Tiwari, Jhillusingh Yadav, Kondapuram Vijaya Raghavan
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Patent number: 6855347Abstract: The present invention relates to a novel synergistic herbal composition for the treatment of gastric ulcer, a method for preparing said synergistic herbal composition and a process for the treatment of gastric ulcer using said composition and more particularly, the present invention relates to a novel synergistic herbal composition which is effective against pyloric ligation induced ulcer model and histamine induced ulcer model.Type: GrantFiled: March 25, 2002Date of Patent: February 15, 2005Assignee: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Upparapalli Sampathkumar, Boggavarapu Subrahmanya Sastry, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan, Gautam Palit, Deepak Rai, Panniyampally Madhavankutty Varier, Trikovil Sankaran Muraleedharan, Kollath Muraleedharan
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Patent number: 6841687Abstract: This invention relates to a process for isolating (?)-epicatechin from a new plant source namely Dichrostachys cinerea in significant yield.Type: GrantFiled: February 24, 2003Date of Patent: January 11, 2005Assignee: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Rao Jagadeeshwar Rao, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan
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Publication number: 20040171674Abstract: The present invention provides novel &agr;-glucosidase inhibitory compound (−)-mesquitol and its analogs isolated in significant yield from traditional medicinal plant Dichrostachys cinerea and further modification of (−)-mesquitol to enhance the &agr;- glucosidase inhibitory potential; the invention also identifies the usage of (−)-mesquitol and its analogues, based on their &agr;-glucosidase inhibitory activity, as broad based potential therapeutics as antihyperglycernic, antidiabatic, antiobesity, antiviral, anticancer, immunestimulants and the like.Type: ApplicationFiled: April 1, 2003Publication date: September 2, 2004Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEAInventors: Janaswamy Madhusudana Rao, Rao Jagadeeshwar Rao, Upparapalli Sampath Kumar, Singireddy Venkat Reddy, Ashok Kumar Tiwari, Jhillusingh Yadav, Kondapuram Vijaya Raghavan
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Patent number: 6781002Abstract: The invention relates to a process for the isolation of (−)-mesquitol in substantial (1.5%) yields from Dichrostachys cinerea and also the usage of (−)-mesquitol as an antioxidant/free-radical scavenger.Type: GrantFiled: February 28, 2003Date of Patent: August 24, 2004Assignee: Council of Scientific & Industrial ResearchInventors: Janaswamy Madhusudana Rao, Rao Jagadeeshwar Rao, Ashok Kumar Tiwari, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan
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Publication number: 20040116717Abstract: This invention relates to a process for isolating (−)-epicatechin from a new plant source namely Dichrostachys cinerea in significant yield.Type: ApplicationFiled: February 24, 2003Publication date: June 17, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Janaswamy Madhusudana Rao, Rao Jagadeeshwar Rao, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan
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Publication number: 20040116716Abstract: The invention relates to a process for the isolation of (−)-mesquitol in substantial (1.5%) yields from Dichrostachys cinerea and also the usage of (−)-mesquitol as an antioxidant/free-radical scavenger.Type: ApplicationFiled: February 28, 2003Publication date: June 17, 2004Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHInventors: Janaswamy Madhusudana Rao, Rao Jagadeeshwar Rao, Ashok Kumar Tiwari, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan
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Publication number: 20040081711Abstract: The present invention relates to a method for providing &agr;-glucosidase inhibition to a subject by administering a pharmaceutical composition comprising a &agr;-glucosidase inhibitory agent selected from pipataline (formula 1a), sesamin (formula 1b), pellitorine (Formula 1c), guineensine (Formula 1d) and brachystamide-B (formula 1e) having therapeutic application for diabetes mellitus, cancer, viral diseases such as hepatitis B and C, HIV, AIDS etc; also the invention provides a process for the isolation of said &agr;-glucosidase inhibitory agent from the plant source Piper longum in significant yields.Type: ApplicationFiled: October 29, 2002Publication date: April 29, 2004Inventors: Janaswamy Madhusudana Rao, Pullela Venkata Srinivas, Vummenthala Anuradha, Ashok Kumar Tiwari, Amtul Zehra Ali, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan
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Publication number: 20030216464Abstract: The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising of (−)-Matairesinol in the range of 9 to 13% by weight, (−)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.Type: ApplicationFiled: June 17, 2003Publication date: November 20, 2003Applicant: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Pullela Venkata Srinivas, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan, A.K. Saxena, M. Shanmugavel, Himani Kampasi, Gulam Nabi Qazi
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Patent number: 6649650Abstract: The present invention relate to a novel synergistic composition of lignans exhibiting anticancer activities for breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate cancer obtained from the plant extract of Cedrus deodra, said composition comprising of (−)-Matairesinol in the range of 9 to 13% by weight, (−)-Wikstromol in the range of 75 to 79% by weight, Dibenzylbutyrolactol in the range of 7 to 11% by weight, and Unidentified material in the range of 2.6 to 3% by weight; further, the synergistic composition of lignan is used in combination with pharmaceutically acceptable carriers for inhibiting growth of various human cancer cell lines selected from breast, cervix, neuroblastoma, colon, liver, lung, mouth, ovary and prostate tissues.Type: GrantFiled: December 7, 2001Date of Patent: November 18, 2003Assignee: Council of Scientific and Industrial ResearchInventors: Janaswamy Madhusudana Rao, Pullela Venkata Srinivas, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan, Ajit Kumar Saxena, Mutiah Shanmugavek, Himani Kampasi, Gulam Nabi Qazi
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Publication number: 20030180398Abstract: The present invention relates to a novel synergistic herbal composition for the treatment of gastric ulcer, a method for preparing said synergistic herbal composition and a process for the treatment of gastric ulcer using said composition and more particularly, the present invention relates to a novel synergistic herbal composition which is effective against pyloric ligation induced ulcer model and histamine induced ulcer model.Type: ApplicationFiled: March 25, 2002Publication date: September 25, 2003Inventors: Janaswamy Madhusudana Rao, Upparapalli Sampathkumar, Boggavarapu Subrahmanya Sastry, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan, Gautam Palit, Deepak Rai, Panniyampally Madhavankutty Varier, Trikovil Sankaran Muraleedharan, Kollath Muraleedharan
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Patent number: 6610330Abstract: The invention relates to an anti-diabetic agent obtained from the plant Humboldtia decurrens, an anti-diabetic formulation comprising an effect amount of the extract obtained from the plant Humboldtia decurrens optionally together with additives, a process for obtaining the anti-diabetic agent, and a method for treatment of diabetes.Type: GrantFiled: November 6, 2001Date of Patent: August 26, 2003Assignees: Council of Scientific & Industrial Research, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala Institute for Research Training and Development Studies of Scheduled Castes and Scheduled TribesInventors: Janaswamy Madhusudana Rao, Mangattu Achutankunju Sumathykutty, Gopalan Vijay Nair, Alathur Damodaran Damodaran, Kodandaraman Rathinam, Rajagopal Sivakumar, Kottilil Mohan Das, Narayanapillai Viswanathan Nair