Patents by Inventor Jane B. Trepel

Jane B. Trepel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of mx gtpases in the prognosis and treatment of cancer
    Publication number: 20040209800
    Abstract: The invention provides a method of reducing cancer progression comprising administering a Mx polypeptide or Mx-encoding nucleic acid to a host, such that the growth rate of the cancer cells is reduced, the metastatic potential of the cancer cells is reduced, or both. The invention also provides a method of assessing the metastatic potential of a cancer comprising (a) obtaining a sample of the cancer, (b) determining the level of Mx, Mx-nucleic acid, or both in the sample, and (c) comparing the level of Mx, Mx-encoding nucleic acid, or both with a control.
    Type: Application
    Filed: April 9, 2004
    Publication date: October 21, 2004
    Inventors: J. Frederic Mushinski, Jane B. Trepel, Michel Andre Horisberger, Phuongmai Nguyen, Chand Khanna
  • Use of purinergic receptor agonists as antineoplastic agents
    Patent number: 5641500
    Abstract: The instant invention is directed to the use of a pharmaceutical composition containing an effective amount of adenosine or an adenosine analog or derivative as an agent useful in the treatment of hormone-independent cancers, such as prostate cancer. The invention is also directed to diagnostic uses of these compounds to determine effective treatment regimes for specific tumors, a process for screening for new, therapeutically useful analogs of these compounds, and the use of these compounds in facilitating the extraction of intracellular components.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: June 24, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jane B. Trepel, Wei-Gang Fang, Farzaneh Pirnia, Charles E. Myers, Jr.
  • Use of purinergic receptor agonists as antineoplastic agents
    Patent number: 5415873
    Abstract: The instant invention is directed to the use of a pharmaceutical composition containing an effective amount of adenosine or an adenosine analog or derivative as an agent useful in the treatment of hormone-independent cancers, such as prostate cancer. The invention is also directed to diagnostic uses of these compounds to determine effective treatment regimes for specific tumors, a process for screening for new, therapeutically useful analogs of these compounds, and the use of these compounds in facilitating the extraction of intracellular components.
    Type: Grant
    Filed: October 4, 1993
    Date of Patent: May 16, 1995
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jane B. Trepel, Wei-Gang Fang, Farzaneh Pirnia, Charles E. Myers, Jr.