Patents by Inventor Jane CULLIS

Jane CULLIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND REAGENTS FOR MODULATING MACROPHAGE PHENOTYPE
    Publication number: 20220031741
    Abstract: The present invention is directed to methods of inducing a phenotypic change in a population of monocytes and; or macrophages. The method includes administering to the population of monocytes and/or macrophages, a macrophage stimulating agent coupled to a carrier molecule, wherein the carrier molecule facilitates macropinocytic uptake of the agent by monocytes and macrophages in the population and is defective in neonatal Fc receptor binding, wherein the administering induces a phenotypic change in the monocytes and macrophages in the population.
    Type: Application
    Filed: August 9, 2021
    Publication date: February 3, 2022
    Inventors: Dafna BAR-SAGI, Jane CULLIS, Craig RAMIREZ
  • Methods and reagents for modulating macrophage phenotype
    Patent number: 11110122
    Abstract: The present invention is directed to methods of inducing a phenotypic change in a population of monocytes and/or macrophages. The method includes administering to the population of monocytes and/or macrophages, a macrophage stimulating agent coupled to a carrier molecule, wherein the carrier molecule facilitates macropinocytic uptake of the agent by monocytes and macrophages in the population and is defective in neonatal Fc receptor binding, wherein the administering induces a phenotypic change in the monocytes and macrophages in the population.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: September 7, 2021
    Assignee: NEW YORK UNIVERSITY
    Inventors: Dafna Bar-Sagi, Jane Cullis, Craig Ramirez
  • METHODS AND REAGENTS FOR MODULATING MACROPHAGE PHENOTYPE
    Publication number: 20190290688
    Abstract: The present invention is directed to methods of inducing a phenotypic change in a population of monocytes and/or macrophages. The method includes administering to the population of monocytes and/or macrophages, a macrophage stimulating agent coupled to a carrier molecule, wherein the carrier molecule facilitates macropinocytic uptake of the agent by monocytes and macrophages in the population and is defective in neonatal Fc receptor binding, wherein the administering induces a phenotypic change in the monocytes and macrophages in the population.
    Type: Application
    Filed: June 5, 2017
    Publication date: September 26, 2019
    Inventors: Dafna BAR-SAGI, Jane CULLIS, Craig RAMIREZ