Abstract: Examples for ensuring robust SRS transmission and reception can occur when coexisting with interference include moving WTRU SRS transmissions out of the interference band to mitigate interference to and from the interferer, increasing the number of OFDM symbols and/or the repetition factor for SRS to overcome the interference, dynamic switching/suspending of semi-persistent SRS and/or aperiodic SRS to mitigate interference to and from the interferer, and power boosting of SRS transmissions to overcome the interference.

Abstract: The present disclosure provides methods of treating B-cell malignancy in a subject with a Bcl-2 inhibitor, in particularly 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-((((1r,4r)-4-hydroxy-4-methylcyclohexyl)methyl)amino)-3-nitrophenyl)sulfonyl)-4-(2-((S)-2-(2-isopropylphenyl)pyrrolidin-1-yl)-7-azaspiro[3.5]nonan-7-yl)benzamide or a pharmaceutically acceptable salt thereof, or its combination with a Bruton's tyrosine kinase (BTK) inhibitor, particularly (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of indolent or aggressive B-cell lymphomas in an individual in need thereof, comprising administering a Btk inhibitor (in particularly (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof) in combination with an anti-PD-1 antibody. The potent and selective BTK inhibitor in combination with the anti-PD-1 antibody have a manageable toxicity profile in patients with indolent and aggressive lymphomas.

Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of indolent or aggressive B-cell lymphomas in an individual in need thereof, comprising administering a Btk inhibitor (in particularly (S)-7-(1-actyloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof) in combination with an anti-PD-1 antibody. The potent and selective BTK inhibitor in combination with the anti-PD-1 antibody have a manageable toxicity profile in patients with indolent and aggressive lymphomas.

Abstract: Systems and methods for maintaining the safety of a software-based system. One method includes automatically generating a first artifact tree for a hazard for a first version of the system and automatically transforming the first artifact tree into a first augmented tree using a set of heuristics. The method also includes automatically generating a second artifact tree for the hazard for a second version of the system and automatically transforming the second artifact tree for the hazard into a second augmented tree using the set of heuristics. The method further includes automatically comparing the first augmented tree and the second augmented tree to generate a delta view, and automatically generating, based on the delta view, at least one selected from a group consisting of a safety warning for the second version of the software-based system and an actionable recommendation to maintain safety of the second version of the software-based system.

Abstract: A multi-functional coaster for a cup or other vessel includes a base upon which the vessel can rest upside down, and a decorative body extending away from the base. The decorative body has at least a first electrically powered signal emitter, which preferably include a light emitter and a sound emitter. The decorative body and/or base can also include a fragrance emitter.

Abstract: Systems and methods for maintaining the safety of a software-based system. One method includes automatically generating a first artifact tree for a hazard for a first version of the system and automatically transforming the first artifact tree into a first augmented tree using a set of heuristics. The method also includes automatically generating a second artifact tree for the hazard for a second version of the system and automatically transforming the second artifact tree for the hazard into a second augmented tree using the set of heuristics. The method further includes automatically comparing the first augmented tree and the second augmented tree to generate a delta view, and automatically generating, based on the delta view, at least one selected from a group consisting of a safety warning for the second version of the software-based system and an actionable recommendation to maintain safety of the second version of the software-based system.

Abstract: A method is disclosed for providing, for display to a content provider, a user interface comprising an option to view new audiences to be added to a plurality of users currently designated to receive content of the content provider, receiving a user selection of the option, and causing display of information identifying the new audiences, the information identifying the new audiences comprises, for each new audience, an audience identifier, an indication of an estimated number of user actions related to the content of the content provider, and an option to request that a corresponding audience be added to the plurality of users currently designated to receive the content of the content provider.

Abstract: Methods, systems, and media for providing audience recommendations are provided.

Abstract: A multi-functional coaster for a cup or other vessel includes a base upon which the vessel can rest upside down, and a decorative body extending away from the base. The decorative body has at least a first electrically powered signal emitter, which preferably include a light emitter and a sound emitter. The decorative body and/or base can also include a fragrance emitter.

Abstract: Systems, methods and computer-readable storage media utilized to train a machine-learning architecture. One method includes receiving, by one or more processing circuits, a data set. The method further includes determining, by the one or more processing circuits, a first portion of the data set associated with a plurality of entities. The method further includes training, by the one or more processing circuits and utilizing the first portion of the data set, an entity model. The method further includes determining, by the one or more processing circuits, a second portion of the data set associated with a first subset of entities and determining a second subset of entities. The method further includes freezing, by the one or more processing circuits, one or more parameters associated with the second subset of entities and training, utilizing the second portion of the data set, the entity model.

Abstract: A method of generating a Virtual Geospatial Information System (VGIS) database for recognizing an object in an image. At least two images are input to the system, one of the images being a base image for scene registration. At least one orthoimage is generated with corresponding digital elevation model (DEM) data in a Virtual Earth Coordinate (VEC) System domain. The at least one orthoimage is registered to produce a registered image set. Georegistered imagery with scene content signatures is output for automated scene content analysis and automated change detection.

Abstract: Systems and methods for maintaining the safety of a software-based system. One method includes automatically generating a first artifact tree for a hazard for a first version of the system and automatically transforming the first artifact tree into a first augmented tree using a set of heuristics. The method also includes automatically generating a second artifact tree for the hazard for a second version of the system and automatically transforming the second artifact tree for the hazard into a second augmented tree using the set of heuristics. The method further includes automatically comparing the first augmented tree and the second augmented tree to generate a delta view, and automatically generating, based on the delta view, at least one selected from a group consisting of a safety warning for the second version of the software-based system and an actionable recommendation to maintain safety of the second version of the software-based system.

Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of indolent or aggressive B-cell lymphomas in an individual in need thereof, comprising administering a Btk inhibitor (in particularly (S)-7-(1-actyloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof) in combination with an anti-PD-1 antibody. The potent and selective BTK inhibitor in combination with the anti-PD-1 antibody have a manageable toxicity profile in patients with indolent and aggressive lymphomas.

Abstract: Food products, apparatus, systems and methods in which a pocketed bun is produced by supplying compressed air into a portion of bread dough to produce an air pocket, cooking the portion to produce an at least partially cooked bun, and cutting the bun into at least two pieces, with each piece having a cavity. Air can be delivered directly inside the portion of bread dough through a tube or to an expandable object (e.g., a balloon). Preferably, the portion of bread dough is placed into an expandable mold controlled by at least an arm operated by a processor. Batches of pocketed buns can be produced by utilizing a device having multiple molds inside a chamber, and multiple stacked chambers or a shelf with multiple floors.

Abstract: A pocketed bun is made by placing a removable insert inside a portion of bread dough, cooking the bread dough to produce a bread bun, cutting the bread bun, and removing the insert from the bread bun. Preferably, the insert is made of a non-edible and non-stick material. The insert is at least partially or completely surrounded by the bread dough before and after cooking. The insert can also be magnetic, so that the insert and the bread dough can be magnetically suspended during cooking in an oven that has one or more suspension magnets.

Abstract: A pocketed bun is made by placing a removable insert inside a portion of bread dough, cooking the bread dough to produce a bread bun, cutting the bread bun, and removing the insert from the bread bun. Preferably, the insert is made of a non-edible and non-stick material. The insert is at least partially or completely surrounded by the bread dough before and after cooking. The insert can also be magnetic, so that the insert and the bread dough can be magnetically suspended during cooking in an oven that has one or more suspension magnets.

Abstract: Food products, apparatus, systems and methods in which a pocketed bun is produced by supplying compressed air into a portion of bread dough to produce an air pocket, cooking the portion to produce an at least partially cooked bun, and cutting the bun into at least two pieces, with each piece having a cavity. Air can be delivered directly inside the portion of bread dough through a tube or to an expandable object (e.g., a balloon). Preferably, the portion of bread dough is placed into an expandable mold controlled by at least an arm operated by a processor. Batches of pocketed buns can be produced by utilizing a device having multiple molds inside a chamber, and multiple stacked chambers or a shelf with multiple floors.

Abstract: The inventive subject matter provides apparatus, systems and methods in which pants have at least a hidden pocket near the end of a pant leg. The hidden pocket has a sealable opening, preferably downward-facing, on the inside of pant leg that is easily assessable from the end of the pant leg. In preferred embodiments, pants have two pockets on each of the pant legs that are connected by a cable which is at least partially covered by a rubber band. The rubber band can be covered by a soft and fluffy material (e.g., velvet). In some embodiments, the pocket has a metalized layer that would at least partially shield the user from electromagnetic radiation produced by an electronic device.

Abstract: The inventive subject matter provides apparatus, systems and methods in which pants have at least a hidden pocket near the end of a pant leg. The hidden pocket has a sealable opening, preferably downward-facing, on the inside of pant leg that is easily assessable from the end of the pant leg. In preferred embodiments, pants have two pockets on each of the pant legs that are connected by a cable which is at least partially covered by a rubber band. The rubber band can be covered by a soft and fluffy material (e.g., velvet). In some embodiments, the pocket has a metalized layer that would at least partially shield the user from electromagnetic radiation produced by an electronic device.