Patents by Inventor Jane P. Bearinger

Jane P. Bearinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12607589
    Abstract: The strip systems, methods, devices and associated kits disclosed herein are used to determine the presence and/or level a target analyte(s) in sample (e.g., a biological sample such as saliva or nasal swab) wherein the target analyte(s) may be a microorganism (e.g., a whole virus) or molecule (e.g., a viral antigen) associated with a healthy state, disease or injury or otherwise altered physiological condition. In certain embodiments, the systems, methods, devices and kits provide one or more improved properties relative to the lateral flow protein and other assays known in the art for the detection, including but not limited to, assay time, ease of use, risk of infection, accuracy, specificity, selectivity, limit of detection of the assay, quantitative detection and the effect of common interferents to the sensor output, cost, simplicity or a combination thereof. In certain embodiments, the systems, assays, methods and kids are multiplexed, i.e.
    Type: Grant
    Filed: January 13, 2022
    Date of Patent: April 21, 2026
    Assignee: Sorrento Therapeutics, Inc.
    Inventors: Mark William Grinstaff, Scott Edward Schaus, Jane P. Bearinger, Augustus Lang, Ziad Al-Shamsie, Dylann Ceriani
  • Publication number: 20240309143
    Abstract: New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling chains by using monomers that are symmetrical and that have matching amine and hydroxl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.
    Type: Application
    Filed: May 22, 2024
    Publication date: September 19, 2024
    Inventors: Thomas S. Wilson, Jane P. Bearinger
  • Publication number: 20240302317
    Abstract: The strip systems, methods, devices and associated kits disclosed herein are used to determine the presence and/or level a target analyte(s) in sample (e.g., a biological sample such as saliva or nasal swab) wherein the target analyte(s) may be a microorganism (e.g., a whole virus) or molecule (e.g., a viral antigen) associated with a healthy state, disease or injury or otherwise altered physiological condition. In certain embodiments, the systems, methods, devices and kits provide one or more improved properties relative to the lateral flow protein and other assays known in the art for the detection, including but not limited to, assay time, ease of use, risk of infection, accuracy, specificity, selectivity, limit of detection of the assay, quantitative detection and the effect of common interferents to the sensor output, cost, simplicity or a combination thereof. In certain embodiments, the systems, assays, methods and kids are multiplexed, i.e.
    Type: Application
    Filed: January 13, 2022
    Publication date: September 12, 2024
    Inventors: Mark William Grinstaff, Scott Edward Schaus, Jane P. Bearinger, Augustus Lang, Ziad Al-Shamsie, Dylann Ceriani
  • Publication number: 20240287240
    Abstract: This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape.
    Type: Application
    Filed: April 9, 2024
    Publication date: August 29, 2024
    Inventors: Thomas S. Wilson, Michael Keith Hearon, Jane P. Bearinger
  • Patent number: 11993673
    Abstract: New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling Chains by using monomers that are symmetrical and that have matching amine and hydroxyl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.
    Type: Grant
    Filed: September 22, 2022
    Date of Patent: May 28, 2024
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Thomas S. Wilson, Jane P. Bearinger
  • Patent number: 11958932
    Abstract: This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: April 16, 2024
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Thomas S. Wilson, Michael Keith Hearon, Jane P. Bearinger
  • Patent number: 11933782
    Abstract: Detector systems are described, based on a primary binding compound and a secondary binding compound used in combination with a support to detect a target in a sample. The detection systems include a liquid medium hosting a first binding compound specific to a target, the first binding compound comprising a label; and a solid medium hosting a second binding compound specific to the target, the second binding compound being different from and non-competitive with respect to the first binding compound.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: March 19, 2024
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventor: Jane P. Bearinger
  • Patent number: 11820852
    Abstract: New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling chains by using monomers that are symmetrical and that have matching amine and hydroxl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.
    Type: Grant
    Filed: September 22, 2022
    Date of Patent: November 21, 2023
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Thomas S. Wilson, Jane P. Bearinger
  • Publication number: 20230141620
    Abstract: This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape.
    Type: Application
    Filed: December 16, 2022
    Publication date: May 11, 2023
    Inventors: Thomas S. Wilson, Michael Keith Hearon, Jane P. Bearinger
  • Publication number: 20230030468
    Abstract: New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling chains by using monomers that are symmetrical and that have matching amine and hydroxl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.
    Type: Application
    Filed: September 22, 2022
    Publication date: February 2, 2023
    Inventors: Thomas S. Wilson, Jane P. Bearinger
  • Publication number: 20230029649
    Abstract: New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling Chains by using monomers that are symmetrical and that have matching amine and hydroxl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.
    Type: Application
    Filed: September 22, 2022
    Publication date: February 2, 2023
    Inventors: Thomas S. Wilson, Jane P. Bearinger
  • Patent number: 11530291
    Abstract: This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: December 20, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Thomas S. Wilson, Michael Keith Hearon, Jane P. Bearinger
  • Patent number: 11453740
    Abstract: New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling chains by using monomers that are symmetrical and that have matching amine and hydroxl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: September 27, 2022
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Thomas S. Wilson, Jane P. Bearinger
  • Patent number: 11320432
    Abstract: Systems are described, based on a primary binding compound and a secondary binding compound used in combination with a support to detect a target in a sample. The systems includes at least one support structure, at least one small primary support portion containing at least one molecule covalently bound to a visual colloidal marker, a plurality of secondary support portions comprising secondary binding compounds that are covalently bound to the support portions and chemically active, at least one pH litmus indicator, at least one pH strip, a buffer for lateral flow on the porous membrane support that allows preservation and activity of binding compounds.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: May 3, 2022
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventor: Jane P. Bearinger
  • Publication number: 20210070918
    Abstract: This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape.
    Type: Application
    Filed: December 2, 2019
    Publication date: March 11, 2021
    Inventors: Thomas S. Wilson, Michael Keith Hearon, Jane P. Bearinger
  • Publication number: 20200131299
    Abstract: New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling chains by using monomers that are symmetrical and that have matching amine and hydroxl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.
    Type: Application
    Filed: December 23, 2019
    Publication date: April 30, 2020
    Inventors: Thomas S. Wilson, Jane P. Bearinger
  • Patent number: 10526437
    Abstract: New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling chains by using monomers that are symmetrical and that have matching amine and hydroxyl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: January 7, 2020
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Thomas S. Wilson, Jane P. Bearinger
  • Patent number: 10494470
    Abstract: This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: December 3, 2019
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Thomas S. Wilson, Michael Keith Hearon, Jane P. Bearinger
  • Patent number: 10161390
    Abstract: A resistively heated shape memory polymer device is operated using resistive heating to heat the shape memory polymer device. The resistively heated shape memory polymer device is made by providing a wire that includes a resistive medium. The wire is coated with a first shape memory polymer. The wire is exposed and electrical leads are attached to the wire. In one embodiment the shape memory polymer device is in the form of a clot destruction device. In another embodiment the shape memory polymer device is in the form of a microvalve. In another embodiment the shape memory polymer device is in the form of a micropump. In yet another embodiment the shape memory polymer device is in the form of a thermostat or relay switch.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 25, 2018
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: John E. Marion, III, Jane P. Bearinger, Thomas S. Wilson, Ward Small, IV, Duncan J. Maitland
  • Patent number: 10107270
    Abstract: A resistively heated shape memory polymer device is operated using resistive heating to heat the shape memory polymer device. The resistively heated shape memory polymer device is made by providing a wire that includes a resistive medium. The wire is coated with a first shape memory polymer. The wire is exposed and electrical leads are attached to the wire. In one embodiment the shape memory polymer device is in the form of a clot destruction device. In another embodiment the shape memory polymer device is in the form of a microvalve. In another embodiment the shape memory polymer device is in the form of a micropump. In yet another embodiment the shape memory polymer device is in the form of a thermostat or relay switch.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: October 23, 2018
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: John E. Marion, III, Jane P. Bearinger, Thomas S. Wilson, Ward Small, IV, Duncan J. Maitland