Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: A system for forming a tendon sleeve on an atmospheric balloon is described herein, the system comprising a coupling assembly including a seam coupling mechanism that forms a seam joint between a first gore panel and a second gore panel, the seam joint is spaced from respective first and second lateral edges of the first and second gore panels to form first and second edge flanges, and an edge coupling mechanism that forms an edge joint between the first and second edge flanges and closes a tendon sleeve, the edge joint spaced from the seam joint, the tendon sleeve includes a tendon sleeve passage between the seam joint and the edge joint and between the first and second edge flanges. The system also includes a tendon positioning mechanism that positions a tendon within the tendon sleeve passage. A tendon sleeve formed by this system is also described herein.

Abstract: Described herein are methods, and compositions for use in the coloration of materials. The compositions described herein are black pigments derived primarily from recently-living plants or animals and are therefore renewable.

Abstract: A system for forming a tendon sleeve on an atmospheric balloon is described herein, the system comprising a coupling assembly including a seam coupling mechanism that forms a seam joint between a first gore panel and a second gore panel, the seam joint is spaced from respective first and second lateral edges of the first and second gore panels to form first and second edge flanges, and an edge coupling mechanism that forms an edge joint between the first and second edge flanges and closes a tendon sleeve, the edge joint spaced from the seam joint, the tendon sleeve includes a tendon sleeve passage between the seam joint and the edge joint and between the first and second edge flanges. The system also includes a tendon positioning mechanism that positions a tendon within the tendon sleeve passage. A tendon sleeve formed by this system is also described herein.

Abstract: A system for forming a tendon sleeve on an atmospheric balloon is described herein, the system comprising a coupling assembly including a seam coupling mechanism that forms a seam joint between a first gore panel and a second gore panel, the seam joint is spaced from respective first and second lateral edges of the first and second gore panels to form first and second edge flanges, and an edge coupling mechanism that forms an edge joint between the first and second edge flanges and closes a tendon sleeve, the edge joint spaced from the seam joint, the tendon sleeve includes a tendon sleeve passage between the seam joint and the edge joint and between the first and second edge flanges. The system also includes a tendon positioning mechanism that positions a tendon within the tendon sleeve passage. A tendon sleeve formed by this system is also described herein.

Abstract: A cleaning tool (100) for a pipe is provided comprising a substantially cylindrical body (102) and a plurality of holes within the body section (102) for receiving resilient biasing means. A plurality of bristle heads (104) extend radially from the body. Each bristle head (104) is movable between an extended position and an inward position and the biasing means bias the bristle heads in the direction of the extended position. A housing may be provided for each resilient biasing means that is received in each of the plurality of the holes in the body.

Abstract: A cleaning apparatus (2) comprising a hollow first cylindrical end collar (4), a hollow second cylindrical end collar (6) and a substantially tubular cleaning section, open at each end, extending therebetween, wherein the tubular cleaning section comprises a plurality of elongate strip brushes (8) disposed between the first cylindrical collar (4) and the second cylindrical collar (6) and arranged such that there are radical openings in the tubular cleaning section between said elongate strip brushes (8).

Abstract: A solar charging handbag for recharging electronic appliances such as cellular telephones, personal digital assistants (PDAs), digital cameras, and Digital Versatile Disc (DVD) players, MP3 players, gaming stations, and similar devices. A solar panel is connected to a charge control module and the electronic appliance is plugged into the charge control module. The charge control module may incorporate a rechargeable battery or battery pack.

Abstract: A cleaning tool (100) for a pipe is provided comprising a substantially cylindrical body (102) and a plurality of holes within the body section (102) for receiving resilient biasing means. A plurality of bristle heads (104) extend radially from the body. Each bristle head (104) is movable between an extended position and an inward position and the biasing means bias the bristle heads in the direction of the extended position. A housing may be provided for each resilient biasing means that is received in each of the plurality of the holes in the body.

Abstract: A cleaning apparatus (2) comprising a hollow first cylindrical end collar (4), a hollow second cylindrical end collar (6) and a substantially tubular cleaning section, open at each end, extending therebetween, wherein the tubular cleaning section comprises a plurality of elongate strip brushes (8) disposed between the first cylindrical collar (4) and the second cylindrical collar (6) and arranged such that there are radical openings in the tubular cleaning section between said elongate strip brushes (8).