Patents by Inventor Jane R. Connor

Jane R. Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers
    Patent number: 7012098
    Abstract: Agents and methods for chemoprevention and treatment of neoplasia are described, the agents including a selective inhibitor of inducible nitric oxide synthase and a combination of a selective inhibitor of inducible nitric oxide synthase and an inhibitor of cylcooxygenase-2 in a pharmaceutical composition. The agents and methods are used for chemoprevention and treatment of neoplasia including colorectal cancer and other cancers affecting epithelial cells throughout the body. The agents can also be used to treat the fibrosis that occurs with radiation therapy, as well as adenomatous polyps, including those with familial adenomatous polyposis (FAP).
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: March 14, 2006
    Assignee: Pharmacia Corporation
    Inventors: Pamela T. Manning, Jane R. Connor, Karen Seibert, Chinthalapally V. Rao, Bandaru S. Reddy
  • Methods of treating osteoarthritis with inducible nitric oxide synthase inhibitors
    Publication number: 20040143017
    Abstract: Methods of treating osteoarthritis by administering an therapeutically effective amount of NOS inhibitor are provided.
    Type: Application
    Filed: September 22, 2003
    Publication date: July 22, 2004
    Inventors: Pamela T. Manning, Mark G. Currie, Jane R. Connor, Jean-Pierre Pelletier, Johanne Martel Pelletier
  • Methods for treatment and prevention of gastrointestinal conditions
    Publication number: 20040127569
    Abstract: Therapeutic methods for the prevention and treatment of conditions and diseases of the gastrointestinal tract involving an overproduction of nitric oxide by inducible nitric oxide synthase are described, the methods including administering to a subject in need thereof a therapeutically effective amount of a selective inhibitor of inducible nitric oxide synthase (iNOS). The methods also include the use of selective inhibitors of iNOS in combination with other therapeutic agents, including antimicrobial agents and antisecretory agents.
    Type: Application
    Filed: July 25, 2003
    Publication date: July 1, 2004
    Inventors: Pamela T. Manning, Jane R. Connor
  • Methods of treating osteoarthritis with inducible nitric oxide synthase inhibitors
    Patent number: 6653350
    Abstract: Methods of treating osteoarthritis by administering an therapeutically effective amount of NOS inhibitor are provided.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: November 25, 2003
    Assignees: G.D. Searle & Co., Pharmacia Corporation
    Inventors: Pamela T. Manning, Jane R. Connor, Mark G. Currie, Jean Pierre Pelletier, Johanne Martel Pelletier
  • Neuroprotective treatment methods using selective iNOS inhibitors
    Publication number: 20030119826
    Abstract: Therapeutic methods for the prevention and treatment of neurodegenerative conditions are described, the methods including administering to a subject in need thereof a neuroprotective effective amount of a selective inhibitor of inducible nitric oxide synthase.
    Type: Application
    Filed: September 24, 2001
    Publication date: June 26, 2003
    Applicant: Pharmacia Corporation
    Inventors: Pamela T. Manning, Jane R. Connor
  • Ophthalmologic treatment methods using selective iNOS inhibitors
    Publication number: 20030109522
    Abstract: Therapeutic methods for the prevention and treatment of ophthalmologic conditions are described, the methods including administering to a subject in need thereof a selective inhibitor of inducible nitric oxide synthase.
    Type: Application
    Filed: September 24, 2001
    Publication date: June 12, 2003
    Inventors: Pamela T. Manning, Jane R. Connor
  • Agents and methods for treatment of cancer
    Publication number: 20030013702
    Abstract: Agents and methods for chemoprevention and treatment of neoplasia are described, the agents including a selective inhibitor of inducible nitric oxide synthase and a combination of a selective inhibitor of inducible nitric oxide synthase and an inhibitor of cylcooxygenase-2 in a pharmaceutical composition. The agents and methods are used for chemoprevention and treatment of neoplasia including colorectal cancer and other cancers affecting epithelial cells throughout the body. The agents can also be used to treat the fibrosis that occurs with radiation therapy, as well as adenomatous polyps, including those with familial adenomatous polyposis (FAP).
    Type: Application
    Filed: September 24, 2001
    Publication date: January 16, 2003
    Inventors: Pamela T. Manning, Jane R. Connor, Karen Seibert, Chinthalapally V. Rao, Bandaru S. Reddy