Patents by Inventor Jane Theaker

Jane Theaker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and primers for detecting target nucleic acid sequences
    Patent number: 9273350
    Abstract: A method for the detection of a target nucleic acid, which method comprises contacting template nucleic acid from a sample with (i) a signalling system and (ii) a tailed nucleic acid primer having a template binding region and the tail comprising a linker and a target binding region, in the presence of appropriate nucleoside triphosphates and an agent for polymerisation thereof, under conditions such that the template binding region of the primer will hybridise to a complementary sequence in the template nucleic acid and be extended to form a primer extension product, separating any such product from the template whereupon the target binding region in the tail of the primer will hybridise to a sequence in the primer extension product corresponding to the target nucleic acid, and wherein any such target specific hybridisation causes a detectable change in the signalling system, such that the presence or absence of the target nucleic acid in the sample is detected by reference to the presence or absence of a de
    Type: Grant
    Filed: June 8, 2004
    Date of Patent: March 1, 2016
    Assignee: QIAGEN MANCHESTER LIMITED
    Inventors: David Mark Whitcombe, Jane Theaker, Neil James Gibson, Stephen Little
  • Methods and primers for detecting target nucleic acid sequences
    Publication number: 20050164219
    Abstract: A method for the detection of a target nucleic acid, which method comprises contacting template nucleic acid from a sample with (i) a signalling system and (ii) a tailed nucleic acid primer having a template binding region and the tail comprising a linker and a target binding region, in the presence of appropriate nucleoside triphosphates and an agent for polymerisation thereof, under conditions such that the template binding region of the primer will hybridise to a complementary sequence in the template nucleic acid and be extended to form a primer extension product, separating any such product from the template whereupon the target binding region in the tail of the primer will hybridise to a sequence in the primer extension product corresponding to the target nucleic acid, and wherein any such target specific hybridisation causes a detectable change in the signalling system, such that the presence or absence of the target nucleic acid in the sample is detected by reference to the presence or absence of a de
    Type: Application
    Filed: June 8, 2004
    Publication date: July 28, 2005
    Applicant: DXS Limited
    Inventors: David Whitcombe, Jane Theaker, Neil Gibson, Stephen Little
  • Methods and primers for detecting target nucleic acid sequences
    Publication number: 20030087240
    Abstract: A method for the detection of a target nucleic acid, which method comprises contacting template nucleic acid from a sample with (i) a signalling system and (ii) a tailed nucleic acid primer having a template binding region and the tail comprising a linker and a target binding region, in the presence of appropriate nucleoside triphosphates and an agent for polymerization thereof, under conditions such that the template binding region of the primer will hybridize to a complementary sequence in the template nucleic acid and be extended to form a primer extension product, separating any such product from the template whereupon the target binding region in the tail of the primer will hybridize to a sequence in the primer extension product corresponding to the target nucleic acid, and wherein any such target specific hybridization causes a detectable change in the signalling system, such that the presence or absence of the target nucleic acid in the sample is detected by reference to the presence or absence of a de
    Type: Application
    Filed: October 12, 2001
    Publication date: May 8, 2003
    Applicant: Zeneca Limited
    Inventors: David Mark Whitcombe, Jane Theaker, Neil James Gibson, Stephen Little
  • Use of 2'-O-methyl RNA as hybridisation probe
    Publication number: 20020102571
    Abstract: Digestion-resistant probes comprising 2′-O-methyl RNA for nucleic acid hybridization assays. Their preparation and use.
    Type: Application
    Filed: June 19, 2001
    Publication date: August 1, 2002
    Inventors: Jane Theaker, Kay Callaghan
  • Methods for detecting target nucleic acid sequences
    Patent number: 6326145
    Abstract: A method for the detection of a target nucleic acid, which method comprises contacting template nucleic acid from a sample with (i) a signalling system and (ii) a tailed nucleic acid primer having a template binding region and the tail comprising a linker and a target binding region, in the presence of appropriate nucleoside triphosphates and an agent for polymerization thereof, under conditions such that the template binding region of the primer will hybridize to a complementary sequence in the template nucleic acid and be extended to form a primer extension product, separating any such product from the template whereupon the target binding region in the tail of the primer will hybridize to a sequence in the primer extension product corresponding to the target nucleic acid, and wherein any such target specific hybridization causes a detectable change in the signalling system, such that the presence or absence of the target nucleic acid in the sample is detected by reference to the presence or absence of a de
    Type: Grant
    Filed: November 25, 1998
    Date of Patent: December 4, 2001
    Assignee: Zeneca Limited
    Inventors: David Mark Whitcombe, Jane Theaker, Neil James Gibson, Stephen Little