Patents by Inventor Jane Visvader

Jane Visvader has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080038230
    Abstract: The present invention relates generally to a method for the generation of a substantially homogenous population of undifferentiated cells. More particularly, the present invention relates to a method for isolating a substantially homogenous population of stem cells, and in particular, mammary stem cells (MaSCs). The MaSCs of the present invention are isolated on the basis of differential levels of proteins present on their cell surface. The MaSCs of the present invention are particularly useful as targets for identifying agents which modulate MaSC survival, self-renewal, proliferation and/or differentiation in both normal and diseased tissue such as, but not limited to, tumor tissue, and, also as source of tissue for the regeneration, replacement and/or augmentation of tissue damaged and/or lost after disease or injury.
    Type: Application
    Filed: May 12, 2005
    Publication date: February 14, 2008
    Applicant: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Geoffrey Lindeman, Mark Shackleton, Francois Vaillant, Jane Visvader
  • Publication number: 20060166917
    Abstract: The present invention discloses methods for modulating the differentiation and/or proliferation of mammary cells, especially of mammary epithelial cells, or for modulating the differentiation and/or proliferation of the lobuloalveolar system, or for modulating mammopoiesis and/or lactogenesis, or for modulating tumorigenesis in a cell which is associated with the reproductive system of a mammal by modulating the expression of a gene or the level and/or functional activity of an expression product of the gene, wherein the gene is selected from SOCS-1 or a gene belonging to the same regulatory or biosynthetic pathway as SOCS-1.
    Type: Application
    Filed: November 3, 2005
    Publication date: July 27, 2006
    Applicant: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Geoffrey Lindeman, Jane Visvader
  • Publication number: 20060148032
    Abstract: The present invention relates generally to cancer therapy and cancer diagnostics and to agents useful therefor. More particularly, the present invention provides a novel tumorigenesis-related phosphoprotein and a nucleic acid molecule encoding same. The present invention also provides diagnostic agents to detect the presence or absence of the tumorigenesis-related phosphoprotein or the presence or absence of an expressible tumorigenesis-related gene encoding the phosphoprotein. Such diagnostic agents are useful in determining the likelihood of development of a tumor in a vertebrate animal such as mammal and, in particular, a human. The diagnostic agents provided by the present invention may be used inter alia in screening and/or predicting the likelihood of development of neoplastic diseases such as but not limited to mammary cancer.
    Type: Application
    Filed: December 12, 2003
    Publication date: July 6, 2006
    Applicant: The Walter and Eliza Hall Institute of Medical Res
    Inventors: Monilola Olayioye, Jane Visvader, Geoffrey Lindeman, Peter Hoffmann, Thomas Pomorski
  • Publication number: 20050048528
    Abstract: The present invention relates generally to a method for detecting an aberrant cell, and more particularly an aberrant epithelial cell, in a subject or in a biological sample from said subject and agents useful for same. More particularly, the present invention relates to a method of deleting an aberrant mammary epithelial cell. The presence of the aberrant cell or group of aberrant cells provides an indication of a particular disease or condition or a propensity for development of a disease or condition.
    Type: Application
    Filed: March 12, 2004
    Publication date: March 3, 2005
    Inventors: Jane Visvader, Geoffrey Lindeman, Eleanor Sum, Lorraine O'Reilly
  • Publication number: 20030175971
    Abstract: The present invention discloses methods for modulating the differentiation and/or proliferation of mammary cells, especially of mammary epithelial cells, or for modulating the differentiation and/or proliferation of the lobuloalveolar system, or for modulating mammopoiesis and/or lactogenesis, or for modulating tumorigenesis in a cell which is associated with the reproductive system of a mammal by modulating the expression of a gene or the level and/or functional activity of an expression product of the gene, wherein the gene is selected from SOCS-1 or a gene belonging to the same regulatory or biosynthetic pathway as SOCS-1.
    Type: Application
    Filed: December 30, 2002
    Publication date: September 18, 2003
    Inventors: Geoffrey Lindeman, Jane Visvader