Abstract: The present disclosure provides compounds and methods useful in the treatment and suppression of cancer, for example, useful for treating or suppressing cancers characterized by KRAS G12C. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Abstract: A method of forming a shaped foamed polymer article and articles obtained from said method.

Abstract: The present disclosure provides compounds and methods useful in the treatment and suppression of cancer, for example, useful for treating or suppressing cancers characterized by KRAS G12C. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Abstract: The present disclosure provides for compounds of the general Formula (I) wherein R1a, R1b, R2, R3, R4, R5, R6, R7, R8, and Ring A have any of the values defined in the specification, and pharmaceutically acceptable salts thereof.

Abstract: A computing system is configured to generate a predictive model during training of a machine learning program using a training data set including a personal data set of a plurality of first users. The predictive model is configured to generate a predicted assessment score with respect to a second user by correlating a personal data set of the second user to the personal data set of at least one of the first users, with the generating of the predicted assessment score occurring automatically when a data entry of the personal data set of the second user is determined to have changed by the computing system. The computing system is configured to report the automatically generated predicted assessment score to the second user via a user device of the second user.

Abstract: The present disclosure provides compounds and methods useful in the treatment and suppression of cancer, for example, useful for treating or suppressing cancers characterized by KRAS G12C. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Abstract: The present invention relates to a consumer product comprising a laminate packaging comprising an outer oriented multilayer film comprising a polyolefin-based polymer; an inner multilayer film comprising a polyolefin-based polymer; and a composition comprising 0.2% to 1.2% by weight of a perfume; wherein the outer and the inner layers are made of the same polyolefin-based polymer, which is ethylene based polymer or propylene based polymer; and wherein the composition is packaged inside the laminate packaging.

Abstract: A “universal” airbag system according to embodiments of the present disclosure provides for occupant protection in both conventional and unconventional seating orientations (rotated, reclined, and lying positions), when impacted in various directions. The universal airbag system features a seat mounted airbag which may be used with a seat-integrated seatbelt. The material may be selected, constructed, and attached such that it does not fail or tear under application-specific loading conditions, is strong enough to capture the occupant, has the elongation/expansion properties for a flexible yet stable shape with excursion limiting functionality, and is optionally inflatable.

Abstract: A “universal” airbag system according to embodiments of the present disclosure provides for occupant protection in both conventional and unconventional seating orientations (rotated, reclined, and lying positions), when impacted in various directions. The universal airbag system features a seat mounted airbag which may be used with a seat-integrated seatbelt. The material may be selected, constructed, and attached such that it does not fail or tear under application-specific loading conditions, is strong enough to capture the occupant, has the elongation/expansion properties for a flexible yet stable shape with excursion limiting functionality, and is optionally inflatable.

Abstract: A process for reducing the permeability to water of a thief zone of a porous and permeable subterranean petroleum reservoir by injecting a dispersion of polymeric microparticles in an aqueous fluid down a well and into the thief zone, wherein the polymeric microparticles comprise crosslinked copolymer chains having structural units derived from (i) a water-soluble or water-dispersible monomer with a betaine group, (ii) a water-insoluble monomer, and, (iii) a cross-linking monomer having at least two sites of ethylenic unsaturation, and the polymeric microparticles have a transition temperature above the maximum temperature encountered in the well and at or below the maximum temperature encountered in the thief zone and, and the polymeric microparticles expand in size in the thief zone when they encounter a temperature at or greater than the transition temperature so as to reduce the permeability of the thief zone to water.

Abstract: A process for reducing the permeability to water of a thief zone of a porous and permeable subterranean petroleum reservoir includes injecting a composition comprising a dispersion of betainised crosslinked polymeric microparticles in an aqueous fluid down a well and into a thief zone. The betainised crosslinked polymeric microparticles have a transition temperature that is at or below the maximum temperature encountered in the thief zone and greater than the maximum temperature encountered in the well. The betainised crosslinked polymeric microparticles are solvated by water, expand in size and optionally aggregate in the thief zone when they encounter a temperature greater than the transition temperature so as to reduce the permeability of the thief zone to water.

Abstract: An airbag system is provided including an inflator mounted in a front compartment of a vehicle and a deployable or fixed chute that defines a passageway from the front compartment of the vehicle to a passenger compartment of the vehicle for an airbag cushion stored proximate the inflator to follow upon inflation of the airbag cushion.

Abstract: A getter composition for gettering hydrogen and water at temperatures greater than 80° C. includes at least one alkaline earth metal oxide or a precursor thereof and at least one transition metal oxide selected from the group consisting of copper oxide, nickel oxide and cobalt oxide or a precursor of the transition metal oxide.

Abstract: Glyphosate adjuvant compositions and methods of making and using the same are disclosed.

Abstract: The present invention relates to physically stable oil dispersions. It also relates to a method for activating bentones that are designed for use with a low polarity organic systems. It also relates to physically stable oil dispersions comprising said activated bentone.

Abstract: An approach to identifying and measuring adherence to software development requirements is presented. A software agent provides a user with product and technical questions. In turn, the user provides product and technical answers, or attributes, which are stored in a repository. A globalization plan generator uses the product and technical attributes to generate a software development plan. In addition, a globalization verification test generator uses the globalization plan to generate a test plan and measure the success of the software product based upon the test plan.

Abstract: The present invention relates to an herbicidal composition comprising a. at least one ALS-inhibiting herbicide; b. at least one HPPD-inhibiting herbicide; c. at least one saturated or unsaturated fatty acid. The present invention further relates to a method of controlling weeds at a locus which comprise applying to the locus a diluted herbicidal composition according to the present invention. The present invention further relates to the use of a saturated or unsaturated fatty acid to chemically stabilise an herbicidal composition comprising at least one sulfonylurea herbicide and at least one HPPD-inhibiting herbicide.

Abstract: The present invention relates to physically stable oil dispersions. It also relates to a method for activating bentones that are designed for use with a low polarity organic systems. It also relates to physically stable oil dispersions comprising said activated bentone.

Abstract: An approach to identifying and measuring adherence to software development requirements is presented. A software agent provides a user with product and technical questions. In turn, the user provides product and technical answers, or attributes, which are stored in a repository. A globalization plan generator uses the product and technical attributes to generate a software development plan. In addition, a globalization verification test generator uses the globalization plan to generate a test plan and measure the success of the software product based upon the test plan.

Abstract: Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1 are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.