Patents by Inventor Janelle J. Bruinsma

Janelle J. Bruinsma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Removal of PCR inhibitors
    Patent number: 8993341
    Abstract: Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors, e.g, compounds that inhibit polymerase chain reaction, from samples comprising nucleic acids. In particular, the technology is directed toward treating crude sample preparations, such as supernatants from homogenized stool samples, with insoluble polyvinylpyrrolidone (PVP) to form PVP-assay inhibitor complexes, and spin filtration to separate the PVP-assay inhibitor complexes from the crude sample preparations to produce clarified samples that exhibit reduced assay inhibition.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: March 31, 2015
    Assignee: Exact Sciences Corporation
    Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II
  • SERIAL ISOLATION OF MULTIPLE DNA TARGETS FROM STOOL
    Publication number: 20150010907
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting multiple DNA targets from human stool samples.
    Type: Application
    Filed: July 10, 2014
    Publication date: January 8, 2015
    Inventors: Graham P. Lidgard, Janelle J. Bruinsma, Michael J. Domanico
  • Serial isolation of multiple DNA targets from stool
    Patent number: 8808990
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for serial extraction of multiple DNA targets from a human stool sample.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: August 19, 2014
    Assignee: Exact Sciences Corporation
    Inventors: Graham P. Lidgard, Janelle J. Bruinsma, Michael J. Domanico
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20140194607
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20140193813
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II, Keith Kopitzke, John Zeis
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20140194608
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 10, 2014
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
  • REMOVAL OF PCR INHIBITORS
    Publication number: 20120288957
    Abstract: Provided herein is technology relating to processing and preparing samples and particularly, but not exclusively, to methods, systems, and kits for removing assay inhibitors from samples comprising nucleic acids.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Applicant: Exact Sciences Corporation
    Inventors: Janelle J. Bruinsma, Hemanth D. Shenoi, Michael J. Domanico, James P. Light, II
  • SERIAL ISOLATION OF MULTIPLE DNA TARGETS FROM STOOL
    Publication number: 20120288867
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting multiple DNA targets from human stool samples.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Graham P. Lidgard, Janelle J. Bruinsma, Michael J. Domanico
  • ISOLATION OF NUCLEIC ACIDS
    Publication number: 20120288868
    Abstract: Provided herein is technology relating to isolating nucleic acids. In particular, the technology relates to methods and kits for extracting nucleic acids from problematic samples such as stool.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 15, 2012
    Applicant: EXACT SCIENCES CORPORATION
    Inventors: Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II