Patents by Inventor Janes G. Stavrianopoulos

Janes G. Stavrianopoulos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligo- or polynucleotides comprising phosphate-moiety labeled nucleotides
    Patent number: 6992180
    Abstract: The present invention provides a nucleotide having the formula, Sig-PM-SM-BASE wherein PM is a phosphate moiety, SM is a sugar moiety and BASE is a pyrimidine, purine or 7-deazapurine moiety. PM is attached to the 3? or the 5? position of the sugar moiety when the nucleotide is a deoxyribonucleotide and at the 2?, 3? or 5? position when the nucleotide is a ribonucleotide. BASE is attached to the 1? position of SM from the N1 position when BASE is a pyrmidine or the N9 position when BASE is a purine or 7-deazapurine. Sig is covalently attached to PM directly or via a chemical linkage, and represents a detectable moiety covalently attached to SM directly or through a linkage group. Also provided are an oligo- or polynucleotide comprising at least one such phosphate-moiety labeled nucleotide, and other compositions including those wherein a polypeptide is terminally ligated or attached to the oligo- or polynucleotide.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 31, 2006
    Assignee: Enzo Life Sciences, Inc. c/o Enzo Biochem, Inc.
    Inventors: Dean Engelhardt, Elazar Rabbani, Stanley Kline, Janes G. Stavrianopoulos, Dollie Kirtikar