Patents by Inventor Janet L. Stein

Janet L. Stein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MiRNA signature expression in cancer
    Patent number: 11976330
    Abstract: Methods and kits for detecting cancer-associated miRNA are disclosed herein. Methods of identifying and treating a human patient at risk for cancer are also disclosed herein.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: May 7, 2024
    Assignee: The University of Vermont and State Agricultural College
    Inventors: Marie E. Wood, Jane B. Lian, Nicholas Farina, Janet L. Stein
  • MIRNA SIGNATURE EXPRESSION IN CANCER
    Publication number: 20200123619
    Abstract: Methods and kits for detecting cancer-associated miRNA are disclosed herein. Methods of identifying and treating a human patient at risk for cancer are also disclosed herein.
    Type: Application
    Filed: April 6, 2018
    Publication date: April 23, 2020
    Applicant: The University of Vermont and State Agricultural College
    Inventors: Marie E. Wood, Jane B. Lian, Nicholas Farina, Janet L. Stein
  • Quantitative assessment of biological function based on the temporal and spatial organization of subnuclear domains
    Patent number: 7813881
    Abstract: The present invention provides a method useful for analysis of punctate distribution of supramolecular complexes that are compartmentalized in nuclear microenvironments. In preferred embodiments the method provides quantitative analysis of the assembly of regulatory machinery within the context of nuclear architecture and to provide a mechanistic link with biological control. In other embodiments, the invention provides a method of identifying a molecule by parameters of its subnuclear distribution, comprising the steps of quantifying organizational parameters of domains within subnuclear distributions of a molecule; performing factor analysis on the quantified organizational parameters; performing discriminant analysis on the quantified organizational parameters; comparing the results of the factor analysis and the results of the discriminant analysis to one or more standards, thereby identifying a molecule by parameters of its subnuclear distribution.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: October 12, 2010
    Assignee: University of Massachusetts
    Inventors: Gary S. Stein, Daniel W. Young, Sayyed K. Zaidi, Amjad Javed, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian
  • Modulation of cellular proliferation
    Publication number: 20040142894
    Abstract: The invention relates to methods and compositions for modulating cellular proliferation using HiNF-P and NPAT. Also included are methods of identifying compounds that modulate cell proliferation by modulating HiNF-P expression and activity.
    Type: Application
    Filed: October 27, 2003
    Publication date: July 22, 2004
    Inventors: Gary S. Stein, Andre J. Van Wijnen, Janet L. Stein, Partha Mitra, Ronglin Xie
  • Isolated nuclear matrix targeting peptide
    Patent number: 6153729
    Abstract: Nuclear matrix targeting peptides (NMTPs) capable of delivering a variety of therapeutic and diagnostic agents, such as transcription regulatory factors, to the nuclear matrix of a cell are disclosed.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: November 28, 2000
    Assignees: St. Jude's Children's Research Hospital, University of Massachusetts
    Inventors: Gary S. Stein, Andre J. van Wijnen, Janet L. Stein, Jane B. Lian, Jeanne Lawrence, Cong-Mei Zeng, Lindsay Shopland, Scott Hiebert, Shari Meyers, Sheldon Penman