Abstract: Modular lighting fixtures include, for example, a section having an elongated member and at least one light source. The elongated member includes an upper portion, a lower portion, an H-shaped cross-section, a longitudinal axis, and a first flange, a second flange, and a web defining a first channel along a first side of the web and the flanges and a second channel along a second side of the web and the flanges. The at least one light source is attached to the upper portion of the elongated member. The section may be a main section, a first upper section, and/or a second upper section. The sections may have a hollow cross-section and the flanges of the sections may be disposed at 90 degrees relative to each other. Methods for use in forming modular lighting fixtures and methods for illumination are also disclosed.

Abstract: A wireless transmit receive unit (WTRU) may receive, via configuration information, at least one prohibition condition configured to prohibit GNSS activity. The GNSS activity may comprise at least one of GNSS acquisition, GNSS reporting, or GNSS assistance information (AI) reporting. The WTRU may identify a trigger related to the GNSS activity. The WTRU may determine whether a prohibition condition is activated. The prohibition condition may comprise a condition based on a prohibition timer, a condition based on GNSS validity duration, or a condition based on a characteristic of the WTRU. When the prohibition condition is determined to be active, the WTRU may perform the GNSS activity in response to an override or termination of the prohibition condition and based on the prohibition condition being determined to be active.

Abstract: Modular lighting fixtures include, for example, a section having an elongated member and at least one light source. The elongated member includes an upper portion, a lower portion, an H-shaped cross-section, a longitudinal axis, and a first flange, a second flange, and a web defining a first channel along a first side of the web and the flanges and a second channel along a second side of the web and the flanges. The at least one light source is attached to the upper portion of the elongated member. The section may be a main section, a first upper section, and/or a second upper section. The sections may have a hollow cross-section and the flanges of the sections may be disposed at 90 degrees relative to each other. Methods for use in forming modular lighting fixtures and methods for illumination are also disclosed.

Abstract: There are provided inter alia compounds of formula (I) and (II) and their use in therapy, particularly for the treatment of viral infection.

Abstract: There are provided inter alia compounds of formula (I) useful as cyclophilin inhibitors.

Abstract: There are provided inter alia compounds of formula (I) and (II) and their use in therapy, particularly for the treatment of viral infection.

Abstract: There are provided inter alia compounds of formula (I) useful as cyclophilin inhibitors.

Abstract: Systems and methods are provided to facilitate the sharing of account features. In one aspect, a system includes a transaction handler to process transactions and a data warehouse to record the transactions and store account data identifying account features of separate accounts, such as a second account having a feature and a first account without this feature. Account holders of the first and second accounts are in a same household and thus, in accordance with a set of rules, eligible to share the account features. A portal is configured to receive a request identifying the first account and to determine whether a transaction initiated in the first account and qualified for a benefit of the account feature is entitled to the benefit; and if so, a notification engine is to transmit a notification message to an account holder of the first account.

Abstract: Systems and methods are provided to facilitate the generation and notification of transactions associated with account features. In one aspect, a system includes a transaction handler to process transactions and a data warehouse to store transaction data recording the transactions, account data identifying at least one account feature of an account, and rules data identifying at least one qualification requirement. The system further includes a feature offer engine to use the rules data to monitor the transactions in the account to identify a first transaction, a notification engine to provide the account holder with an offer associated with a first account feature in real time with processing of the first transaction, and a portal to receive an approval of a second transaction in accordance with the offer.

Abstract: Systems and methods are provided to facilitate the sharing of account features. In one aspect, a system includes a transaction handler to process transactions and a data warehouse to record the transactions and store account data identifying account features of separate accounts, such as a second account having a feature and a first account without this feature. Account holders of the first and second accounts are in a same household and thus, in accordance with a set of rules, eligible to share the account features. A portal is configured to receive a request identifying the first account and to determine whether a transaction initiated in the first account and qualified for a benefit of the account feature is entitled to the benefit; and if so, a notification engine is to transmit a notification message to an account holder of the first account.

Abstract: The present invention relates to production of polyketides and other natural products and to libraries of compounds and individual novel compounds. Therefore in aspect the present invention provides 17-desmethylrapamycin and analogues thereof, methods for their production, including recombinant strains, and isolation and uses of the compounds of the invention. In a further aspect the present invention provides for the use of 17-desmethylrapamycin and analogues thereof in the induction or maintenance of immunosuppression, the stimulation of neuronal regeneration or the treatment of cancer, B-cell malignancies, fungal infections, transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation vascular disease and fibrotic diseases, and in the regulation of wound healing.

Abstract: The present invention relates to production of polyketides and other natural products and to libraries of compounds and individual novel compounds. Therefore in aspect the present invention provides 17-desmethylrapamycin and analogues thereof, methods for their production, including recombinant strains, and isolation and uses of the compounds of the invention. In a further aspect the present invention provides for the use of 17-desmethylrapamycin and analogues thereof in the induction or maintenance of immunosuppression, the stimulation of neuronal regeneration or the treatment of cancer, B-cell malignancies, fungal infections, transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation vascular disease and fibrotic diseases, and in the regulation of wound healing.

Abstract: The present invention relates to 21-deoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and or prophylaxis of cancer or B-cell malignancies.

Abstract: A waterproof case comprises a pair of flexible waterproof elongated sidewalls extending from a first end and tapering toward a second end. The firearm case includes a waterproof seal about it's peripherally and includes a waterproof closure extending across the sidewall. The firearm case also includes a carrying handle along a reinforced top edge, a shoulder strap connected to the top edge at one end and to a reinforcing strap that extends along the sidewall at a second end. Also disclosed is a waterproof bag having a one piece angular sidewall that is rolled to form a tube and sealed along a seam. The bag also includes a pair of circular end walls sealed to the sidewall and a waterproof zipper that is sealed to the sidewall. The overall structure seals out moisture to prevent the contents within the bag from getting wet. The bag also includes a carrying strap that is secured to a pair of sealing strips that are then in turn sealed to the sidewall.

Abstract: An exercise apparatus comprising a substantially planar panel having a first major surface, a second major surface, first and second grips for receiving the hands of a user and at least one opening extending through the panel from the first major surface to the second major surface, and a shudder carried by the panel and movable between first and second positions for controlling the size of the opening for controlling the resistance to movement of the panel through a viscous fluid.