Patents by Inventor Janet Sinsheimer

Janet Sinsheimer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETIC VARIANTS ASSOCIATED WITH HUMAN-DIRECTED HYPER-SOCIAL BEHAVIOR IN DOMESTIC DOGS
    Publication number: 20200131573
    Abstract: Disclosed herein are structural variants in the Williams-Beuren Syndrome locuse of the dog genome that are associated with hyper-social behavior in dogs relative to wolves, and that are informative regarding the nature of social behavior in dogs. Disclosed also is a commercial test with these loci as indicators along the spectrum of sociality. Methods of breeding dogs to select for dogs having increased sociability are also disclosed.
    Type: Application
    Filed: June 29, 2018
    Publication date: April 30, 2020
    Applicants: The Trustees of Princeton University, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oregon State University
    Inventors: Bridgett vonHOLDT, Monique UDELL, Janet SINSHEIMER
  • Method to estimate age of individual based on epigenetic markers in biological sample
    Patent number: 10435743
    Abstract: The invention provides methods and materials that use observation of DNA characteristics to obtain information relating to the age of individuals. The instant disclosure identifies 88 sites in or near 80 genes for which the degree of cytosine methylation in epithelial and/or white blood cells is significantly correlated with age. In illustrative embodiments of the invention, cytosine methylation patterns the promoters of the EDARADD, TOMILI, and NPTX2 genes are used to predict the age of an individual with a high degree of accuracy.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: October 8, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Eric Vilain, Sven Bocklandt, Steve Horvath, Janet Sinsheimer
  • METHOD TO ESTIMATE AGE OF INDIVIDUAL BASED ON EPIGENETIC MARKERS IN BIOLOGICAL SAMPLE
    Publication number: 20140228231
    Abstract: The invention provides methods and materials that use observation of DNA characteristics to obtain information relating to the age of individuals. The instant disclosure identifies 88 sites in or near 80 genes for which the degree of cytosine methylation in epithelial and/or white blood cells is significantly correlated with age. In illustrative embodiments of the invention, cytosine methylation patterns the promoters of the EDARADD, TOMILI, and NPTX2 genes are used to predict the age of an individual with a high degree of accuracy.
    Type: Application
    Filed: May 18, 2012
    Publication date: August 14, 2014
    Applicant: The Regents of the University of California
    Inventors: Eric Vilain, Sven Bocklandt, Steve Horvath, Janet Sinsheimer