Patents by Inventor Janette M McAllister

Janette M McAllister has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DIAGNOSIS AND/OR THERAPY OF DISORDERS THAT CORRELATE WITH DENNDIA VARIANT 2
    Publication number: 20220143067
    Abstract: Methods for the diagnosis and treatment of DENND1A. V2 related disorders, such as PCOS, are provided. In particular, microRNAs which are upregulated or downregulated in DENND1A. V2 related disorders and methods for using the same are provided.
    Type: Application
    Filed: February 20, 2020
    Publication date: May 12, 2022
    Inventors: Jerome F. STRAUSS, Janette M. MCALLISTER
  • Compositions and methods relating to DENND1A variant 2 and polycystic ovary syndrome
    Patent number: 10865448
    Abstract: Provided are compositions and methods for use in polycystic ovary syndrome diagnosis (PCOS). The method involves a sample from a subject for a DENND1A Variant 2 mRNA or DENND1 A Variant 2 protein to make or aid in a diagnosis of PCOS. Also provided are methods for selecting an individual as a candidate for therapy for polycystic ovary syndrome by testing a biological sample from an individual for DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein and designating the individual as a candidate for the PCOS based on determining DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein in the sample. Also provided are products for use in aiding diagnosis of PCOS which contain reagents for detecting DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein, and packaging containing printed material describing use and indications for the product.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: December 15, 2020
    Assignees: THE PENN STATE RESEARCH FOUNDATION, VIRGINIA COMMONWEALTH UNIVERSITY
    Inventors: Janette M McAllister, Jerome F Strauss
  • Method for diagnosis of polycystic ovary syndrome (PCOS) by measuring levels of DENN/MADD domain containing 1A variant 2 (DENND1A variant 2)
    Patent number: 10723790
    Abstract: Pharmaceutical compositions and methods for the treatment of DENND1A.V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1A.V2 and methods for using the same are provided.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: July 28, 2020
    Assignees: VIRGINIA COMMONWEALTH UNIVERSITY, THE PENN STATE RESEARCH FOUNDATION
    Inventors: Janette M. McAllister, Jerome F. Strauss, Neil D. Christensen
  • Compositions and Methods for Prophylaxis and/or Therapy of Disorders that Correlate with DENND1A Variant 2
    Publication number: 20190092844
    Abstract: Pharmaceutical compositions and methods for the treatment of DENND1A.V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1A.V2 and methods for using the same are provided.
    Type: Application
    Filed: November 27, 2018
    Publication date: March 28, 2019
    Inventors: Janette M. MCALLISTER, Jerome F. STRAUSS, Neil D. CHRISTENSEN
  • Antibodies that recognize a DENN/MADD-domain-containing 1A variant 2 (DENND1A variant 2)
    Patent number: 10183991
    Abstract: Pharmaceutical compositions and methods for the treatment of DENND1A.V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1A.V2 and methods for using the same are provided.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: January 22, 2019
    Assignees: Virginia Commonwealth University, The Penn State Research Foundation
    Inventors: Janette M. McAllister, Jerome F. Strauss, Neil D. Christensen
  • COMPOSITIONS AND METHODS RELATING TO DENND1A VARIANT 2 AND POLYCYSTIC OVARY SYNDROME
    Publication number: 20180216189
    Abstract: Provided are compositions and methods for use in polycystic ovary syndrome diagnosis (PCOS). The method involves a sample from a subject for a DENND1A Variant 2 mRNA or DENND1 A Variant 2 protein to make or aid in a diagnosis of PCOS. Also provided are methods for selecting an individual as a candidate for therapy for polycystic ovary syndrome by testing a biological sample from an individual for DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein and designating the individual as a candidate for the PCOS based on determining DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein in the sample. Also provided are products for use in aiding diagnosis of PCOS which contain reagents for detecting DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein, and packaging containing printed material describing use and indications for the product.
    Type: Application
    Filed: March 15, 2018
    Publication date: August 2, 2018
    Inventors: Janette M. McAllister, Jerome F. Strauss
  • Methods relating to DENND1A Variant 2 and polycystic ovary syndrome
    Patent number: 9957567
    Abstract: Provided are compositions and methods for use in polycystic ovary syndrome diagnosis (PCOS). The method involves a sample from a subject for a DENND1A Variant 2 mRNA or DENND1 A Variant 2 protein to make or aid in a diagnosis of PCOS. Also provided are methods for selecting an individual as a candidate for therapy for polycystic ovary syndrome by testing a biological sample from an individual for DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein and designating the individual as a candidate for the PCOS based on determining DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein in the sample. Also provided are products for use in aiding diagnosis of PCOS which contain reagents for detecting DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein, and packaging containing printed material describing use and indications for the product.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 1, 2018
    Assignees: VIRGINIA COMMONWEALTH UNIVERSITY, THE PENN STATE RESEARCH FOUNDATION
    Inventors: Janette M McAllister, Jerome F Strauss
  • Compositions and Methods for Prophylaxis and/or Therapy of Disorders that Correlate with DENND1A Variant 2
    Publication number: 20170253648
    Abstract: Pharmaceutical compositions and methods for the treatment of DENND1A.V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1A.V2 and methods for using the same are provided.
    Type: Application
    Filed: May 9, 2017
    Publication date: September 7, 2017
    Inventors: Janette M. MCALLISTER, Jerome F. STRAUSS, Neil D. CHRISTENSEN
  • Pharmaceutical compositions comprising DENND1A variant 2 and methods of use thereof
    Patent number: 9676844
    Abstract: Pharmaceutical compositions and methods for the treatment of DENND1 A. V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1 A. V2 and methods for using the same are provided.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: June 13, 2017
    Assignees: Virginia Commonwealth University, The Penn State Research Foundation
    Inventors: Janette M. McAllister, Jerome F. Strauss, Neil D. Christensen
  • COMPOSITIONS AND METHODS FOR PROPHYLAXIS AND/OR THERAPY OF DISORDERS THAT CORRELATE WITH DENND1A VARIANT 2
    Publication number: 20160297873
    Abstract: Pharmaceutical compositions and methods for the treatment of DENND1 A. V2 related disorders, such as PCOS, are provided. In particular, humanized and mouse monoclonal antibodies specific for DENND1 A. V2 and methods for using the same are provided.
    Type: Application
    Filed: November 19, 2014
    Publication date: October 13, 2016
    Applicants: Virginia Commonwealth University, The Penn State Research Foundation
    Inventors: Janette M. MCALLISTER, Jerome F. STRAUSS, Neil D. CHRISTENSEN
  • COMPOSITIONS AND METHODS RELATING TO DENND1A VARIANT 2 AND POLYCYSTIC OVARY SYNDROME
    Publication number: 20150087718
    Abstract: Provided are compositions and methods for use in polycystic ovary syndrome diagnosis (PCOS). The method involves a sample from a subject for a DENND1A Variant 2 mRNA or DENND1 A Variant 2 protein to make or aid in a diagnosis of PCOS. Also provided are methods for selecting an individual as a candidate for therapy for polycystic ovary syndrome by testing a biological sample from an individual for DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein and designating the individual as a candidate for the PCOS based on determining DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein in the sample. Also provided are products for use in aiding diagnosis of PCOS which contain reagents for detecting DENND1 A Variant 2 mRNA or DENND1 A Variant 2 protein, and packaging containing printed material describing use and indications for the product.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 26, 2015
    Inventors: Janette M McAllister, Jerome F Strauss