Abstract: The present invention provides a novel flow cytometry system having high sample cell throughput with simultaneous single and multi-parameter development, extraction and analysis. The invention is comprised of one or more analytic modules or chips aggregated into a stack or chain creating a common laser light transmission channel while maintaining a separate fluid sample flow path within each chip. Each flow chip includes an array of optical fiber light receivers. Each chip also includes integrated waveguides to receive and channel scatter, reflected or fluoresced light of specific frequency and wavelength to the optical fiber receiver. One or more waveguides and optical fiber receivers may be incorporated within each flow chip. Each sensing optical fiber delivers its received light emission to an electro-optical system signal processing module for measuring, digitizing and identifying the light signal.

Abstract: Improved magnetic separators, devices and methods for magnetic separation procedures are provided. The improved separation devices contain matrices which provide uniform pores or channels that reduce the entrapment of air or non-target substances, and decrease the loss of target substances due to mechanical disruption. Target cells, from various systems and organs, or other target biological substances are labeled in conjunction with a suitable specific binding member, and isolated using the devices and methods of the present invention. In its simplest form, the cell separation system of the present invention has two main components: a magnetic separator and a cell separation reagent. A more complex separation device includes fluid passages, collection and storage containers and the separation column. The fluid circuitry can be constructed with integrated valves, or the valves may be applied externally to the fluid pathways.