Patents by Inventor Janez Mravljak

Janez Mravljak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilization of Pharmaceutical Compositions Comprising Polysorbate
    Publication number: 20230137216
    Abstract: The present invention relates to stabilized pharmaceutical compositions comprising an improved histidine-based buffer system that reduces the degradation of polysorbates.
    Type: Application
    Filed: March 15, 2021
    Publication date: May 4, 2023
    Inventors: Roman Sink, Ema Valentina Brovc, Stane Pajk, Janez Mravljak
  • PROCESS FOR THE SYNTHESIS OF EZETIMIBE AND INTERMEDIATES USEFUL THEREFOR
    Publication number: 20110183956
    Abstract: The present invention discloses novel and useful intermediates for the synthesis of ezetimibe (EZT), which intermediates share a characteristic Z-isomeric structure. Based on Z-5-(4-fluorophenyl)-pent-4-enoic acid, and proceeding the synthesis through further Z-intermediates, a total synthesis is presented to obtained final ezetimibe in high yields.
    Type: Application
    Filed: July 29, 2009
    Publication date: July 28, 2011
    Inventors: Janez Mravljak, Matej Sova, Andreja Kovac, Stanislav Gobec, Zdenko Casar