Patents by Inventor Jang Han
Jang Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11944460Abstract: A method for determining a sharpness index of a pulse wave signal includes receiving a pulse wave signal; determining a first reference line starting point and a second reference line starting point on the basis of a curvature of the pulse wave signal; determining a first reference line connecting the first reference line starting point and a first reference line ending point by determining the first reference line ending point by applying an intersecting tangent method to the first reference line starting point, and determining a second reference line connecting the second reference line starting point and a second reference line ending point by determining the second reference line ending point by applying the intersecting tangent method to the second reference line starting point; and determining a sharpness index by using a peak point of the pulse wave signal, the first reference line, and the second reference line.Type: GrantFiled: September 18, 2018Date of Patent: April 2, 2024Assignee: Korea Institute of Oriental MedicineInventors: Jang Han Bae, Young Ju Jeon, Jong Yeol Kim
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Publication number: 20230323300Abstract: The present invention relates to a method for in vitro production of red blood cells. The method for in vitro production of red blood cells, according to the present invention, specifies, by cell size, the maturation step of cells exhibiting optimal effects in an agitation-type culture, so that even if an expert does not always identify cell shape, automated processes of culturing are possible, and thus automation in bioreactors is possible in the mass-production of uniform quality and red blood cells.Type: ApplicationFiled: August 17, 2021Publication date: October 12, 2023Applicant: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)Inventors: Eun Jung BAEK, Eun MI LEE, So Yeon HAN, Won-Seok CHOI, Jang Han LEE, Hyo Sang LEE
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Patent number: 11043668Abstract: A silicon oxide composite for a secondary battery negative electrode material and a method for manufacturing the same, more particularly, a silicon oxide composite for a secondary battery negative electrode material and a method for manufacturing the same are disclosed. The silicon oxide composite includes MgSiO3 (enstatite) crystals and silicon particles, of which crystal size is from 1 to 25 nm, in a silicon oxide (SiOx, 0<x<2), and a carbon film placed on a surface.Type: GrantFiled: March 28, 2017Date of Patent: June 22, 2021Assignee: Daejoo Electronic Material Co., Ltd.Inventors: Seung Min Oh, Jang Han Kim, Daeun Kim
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Patent number: 11021843Abstract: Disclosed is a crashworthy post, which allows a post body to slide rearward along with a vehicle at the early stage of a vehicle collision, and simultaneously a compressive deforming pipe is compressed to dissipate impact energy.Type: GrantFiled: December 16, 2019Date of Patent: June 1, 2021Assignees: KOREA INSTITUTE OF CIVIL ENGINEERING AND BUILDING TECHNOLOGY, KONGJU NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATIONInventors: Jung-Gon Sung, Duk-Geun Yun, Jae-Hong Park, Suk-Ki Lee, Jae-Pil Moon, Choong-Heon Yang, Man-Gi Ko, Kee-Dong Kim, Ki-Jang Han, Min-Hyung No
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Publication number: 20200245948Abstract: A method for determining a sharpness index of a pulse wave signal according to an embodiment comprises the steps of: receiving a pulse wave signal; determining a first reference line starting point and a second reference line starting point on the basis of a curvature of the pulse wave signal; determining a first reference line connecting the first reference line starting point and a first reference line ending point by determining the first reference line ending point by applying an intersecting tangent method to the first reference line starting point, and determining a second reference line connecting the second reference line starting point and a second reference line ending point by determining the second reference line ending point by applying the intersecting tangent method to the second reference line starting point; and determining a sharpness index by using a peak point of the pulse wave signal, the first reference line, and the second reference line.Type: ApplicationFiled: September 18, 2018Publication date: August 6, 2020Applicant: Korea Institute of Oriental MedicineInventors: Jang Han Bae, Young Ju Jeon, Jong Yeol Kim
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Publication number: 20200190753Abstract: Disclosed is a crashworthy post, which allows a post body to slide rearward along with a vehicle at the early stage of a vehicle collision, and simultaneously a compressive deforming pipe is compressed to dissipate impact energy.Type: ApplicationFiled: December 16, 2019Publication date: June 18, 2020Inventors: Jung-Gon SUNG, Duk-Geun YUN, Jae-Hong PARK, Suk-Ki LEE, Jae-Pil MOON, Choong-Heon YANG, Man-Gi KO, Kee-Dong KIM, Ki-Jang HAN, Min-Hyung NO
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Patent number: 10438152Abstract: Techniques are described for facilitating performance of tasks involving human review of media data (e.g., images, audio clips, video clips, etc.), such as to identify one or more targets of interest. The media data review may be performed for various reasons, such as to assist in locating one or more target objects in a large geographical area (e.g., one or more missing people or vehicles) based on human review of large quantities of images that each correspond to a small subset of the geographical area. When one or more of the reviewed media data pieces are identified as being relevant, information about those identified media data pieces may be used in various ways. Furthermore, in at least some situations, the media data review may be part of a charitable effort that uses human volunteers to review the media data without monetary payment or other compensation.Type: GrantFiled: January 25, 2008Date of Patent: October 8, 2019Assignee: Amazon Technologies, Inc.Inventors: Nicole A. Deflaux, James R. Blair, Jang Han Goo, Mark Chien, Luis Felipe Cabrera, Mohamed Reza Hussein
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Publication number: 20190157698Abstract: The present invention relates to a core-shell structured composite powder for a solid oxide fuel cell (SOFC) and more particularly, to a core-shell structured composite powder for a SOFC having a new structure in which nickel, zirconium and yttrium are stably formed in a core shell structure to improve sinterability and conductivity while preventing a fuel electrode from being deformed due to coarsening and contraction of nickel during operation.Type: ApplicationFiled: August 10, 2016Publication date: May 23, 2019Applicant: DAEJOO ELECTRONIC MATERIALS CO., LTD.Inventors: Seung Min Oh, Young Ho Lee, Chi Ho Yoon, Jin Ho Kwak, Jang Han Kim
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Publication number: 20180310838Abstract: Disclosed are a pressing method and a pressing apparatus for measuring pressure pulse waves by continuously pressing, with a constant velocity, an object such as the human body by using a pressing tool, and then identifying a point when the amplitude of the pressure pulse wave being measured changes from increasing to decreasing, to accurately recognize a pressure reducing control point for the pressing tool so that the amplitude of the pressure pulse wave is retained at an appropriate level while measuring. The pressing method comprises the steps of: measuring a pressure pulse wave from an object; determining a pressure reducing point when the amplitude of the pressure pulse wave that is measured changes from increasing to decreasing, while pressure is applied to the object by the pressing tool; and controlling the pressing tool so that pressure applied to the object is decreased after the pressure decreasing point.Type: ApplicationFiled: December 5, 2014Publication date: November 1, 2018Inventors: Young Ju Jeon, Jang Han Bae, Jae Uk Kim, Young Min Kim, Jong Yeol Kim
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Publication number: 20180269475Abstract: A silicon oxide composite for a secondary battery negative electrode material and a method for manufacturing the same, more particularly, a silicon oxide composite for a secondary battery negative electrode material and a method for manufacturing the same are disclosed. The silicon oxide composite includes MgSiO3 (enstatite) crystals and silicon particles, of which crystal size is from 1 to 25 nm, in a silicon oxide (SiOx, 0<x<2), and a carbon film placed on a surface.Type: ApplicationFiled: March 28, 2017Publication date: September 20, 2018Applicant: Daejoo Electronic Material Co., Ltd.Inventors: Seung Min Oh, Jang Han Kim, Daeun Kim
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Publication number: 20150376621Abstract: The present invention provides double-stranded RNA molecules that mediate RNA interference in target cells, preferably hepatic cells. The invention also provides double-stranded RNA (dsRNA) molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis C virus (HCV). The invention also provides a method of using these modified RNA molecules to inactivate virus in mammalian cells and a method of making modified small interfering RNAs (siRNAs) using human Dicer. The invention provides modified RNA molecules that are modified to include a dsRNA or siRNA wherein one or more of the pyrimidines in the RNA molecule are modified to include 2?-Fluorine. The invention also provides dsRNA or siRNA in which all pyrimidines are modified to include a 2?-Fluorine. The invention provides that the 2?-Fluorine dsRNA or siRNA molecule is further modified to include a two base deoxynucleotide “TT” sequence at the 3? end of the molecule.Type: ApplicationFiled: May 14, 2015Publication date: December 31, 2015Applicant: ARROWHEAD RESEARCH CORPORATIONInventors: Jang HAN, Michael HOUGHTON
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Publication number: 20150361432Abstract: The present invention provides double-stranded RNA molecules that mediate RNA interference in target cells, preferably hepatic cells. The invention also provides double-stranded RNA (dsRNA) molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis C virus (HCV). The invention also provides a method of using these modified RNA molecules to inactivate virus in mammalian cells and a method of making modified small interfering RNAs (siRNAs) using human Dicer. The invention provides modified RNA molecules that are modified to include a dsRNA or siRNA wherein one or more of the pyrimidines in the RNA molecule are modified to include 2?-Fluorine. The invention also provides dsRNA or siRNA in which all pyrimidines are modified to include a 2?-Fluorine. The invention provides that the 2?-Fluorine dsRNA or siRNA molecule is further modified to include a two base deoxynucleotide “TT” sequence at the 3? end of the molecule.Type: ApplicationFiled: August 6, 2015Publication date: December 17, 2015Inventors: Jang Han, Mi-Young Seo, Michael Houghton
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Patent number: 9139833Abstract: The present invention provides double-stranded RNA molecules that mediate RNA interference in target cells, preferably hepatic cells. The invention also provides double-stranded RNA molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis C virus (HCV). The invention also provides a method of using these modified RNA molecules to inactivate virus in mammalian cells and a method of making modified small interfering RNAs (siRNAs) using human Dicer.Type: GrantFiled: March 12, 2013Date of Patent: September 22, 2015Assignee: Arrowhead Research CorporationInventors: Jang Han, Mi-Young Seo, Michael Houghton
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Patent number: 9084808Abstract: The present invention provides double-stranded RNA molecules that mediate RNA interference in target cells, preferably hepatic cells. The invention also provides double-stranded RNA (dsRNA) molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis C virus (HCV). The invention also provides a method of using these modified RNA molecules to inactivate virus in mammalian cells and a method of making modified small interfering RNAs (siRNAs) using human Dicer. The invention provides modified RNA molecules that are modified to include a dsRNA or siRNA wherein one or more of the pyrimidines in the RNA molecule are modified to include 2?-Fluorine. The invention also provides dsRNA or siRNA in which all pyrimidines are modified to include a 2?-Fluorine. The invention provides that the 2?-Fluorine dsRNA or siRNA molecule is further modified to include a two base deoxynucleotide “TT” sequence at the 3? end of the molecule.Type: GrantFiled: May 9, 2014Date of Patent: July 21, 2015Assignee: Arrowhead Research CorporationInventors: Jang Han, Michael Houghton
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Publication number: 20150148402Abstract: The present invention provides double-stranded RNA molecules that mediate RNA interference in target cells, preferably hepatic cells. The invention also provides double-stranded RNA (dsRNA) molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis C virus (HCV). The invention also provides a method of using these modified RNA molecules to inactivate virus in mammalian cells and a method of making modified small interfering RNAs (siRNAs) using human Dicer. The invention provides modified RNA molecules that are modified to include a dsRNA or siRNA wherein one or more of the pyrimidines in the RNA molecule are modified to include 2?-Fluorine. The invention also provides dsRNA or siRNA in which all pyrimidines are modified to include a 2?-Fluorine. The invention provides that the 2?-Fluorine dsRNA or siRNA molecule is further modified to include a two base deoxynucleotide “TT” sequence at the 3? end of the molecule.Type: ApplicationFiled: May 9, 2014Publication date: May 28, 2015Applicant: NOVARTIS AGInventors: Jang HAN, Michael HOUGHTON
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Publication number: 20150088014Abstract: The present invention relates to a pulse depth index extraction device and method using pressure at a constant velocity. A device comprises: a pressure applying unit for applying a pressure at a constant velocity to a confirmed pulse location in a direction perpendicular to the skin; a pressure pulse wave signal measuring unit for measuring a pressure pulse wave signal generated based on the applied pressure; and a measured signal analysis unit for deriving the pulse depth index (PDI) by using the measured pressure pulse wave signal.Type: ApplicationFiled: May 8, 2013Publication date: March 26, 2015Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINEInventors: Young Ju Jeon, Jae Uk Kim, Jang Han Bae, Young Min Kim, Jong Yeol Kim, Si Woo Lee
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Patent number: 8765704Abstract: The present invention provides double-stranded RNA molecules that mediate RNA interference in target cells, preferably hepatic cells. The invention also provides double-stranded RNA (dsRNA) molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis C virus (HCV). The invention also provides a method of using these modified RNA molecules to inactivate virus in mammalian cells and a method of making modified small interfering RNAs (siRNAs) using human Dicer. The invention provides modified RNA molecules that are modified to include a dsRNA or siRNA wherein one or more of the pyrimidines in the RNA molecule are modified to include 2?-Fluorine. The invention also provides dsRNA or siRNA in which all pyrimidines are modified to include a 2?-Fluorine. The invention provides that the 2?-Fluorine dsRNA or siRNA molecule is further modified to include a two base deoxynucleotide “TT” sequence at the 3? end of the molecule.Type: GrantFiled: December 14, 2011Date of Patent: July 1, 2014Assignee: Novartis AGInventors: Jang Han, Michael Houghton
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Publication number: 20140073683Abstract: The present invention provides double-stranded RNA molecules that mediate RNA interference in target cells, preferably hepatic cells. The invention also provides double-stranded RNA molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis C virus (HCV). The invention also provides a method of using these modified RNA molecules to inactivate virus in mammalian cells and a method of making modified small interfering RNAs (siRNAs) using human Dicer.Type: ApplicationFiled: March 12, 2013Publication date: March 13, 2014Inventors: Jang HAN, Mi-Young SEO, Michael HOUGHTON
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Patent number: 8481050Abstract: A tissue culture system for production of infectious hepatitis C virus is described. In particular, the invention provides recombinant monocistronic and bicistronic genomic constructs for production of virus, including constructs for production of wild-type HCV type 2a strain JFH1 and constructs for production of chimeric viruses comprising HCV proteins from strain JFH1 and a second HCV isolate. Constructs of the invention also include a reporter gene to facilitate measurement of RNA replication and viral infectivity in cultures. The cell culture system may also include various factors that improve viral replication or infectivity. In addition, a neutralization assay using HCV grown in cell culture is described.Type: GrantFiled: August 22, 2007Date of Patent: July 9, 2013Assignee: Novartis Vaccines and Diagnostics, Inc.Inventors: Qui-Lim Choo, Jang Han, Michael Houghton, Taewoo Kwon, Hyun Chul Song, Yifei Zhu
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Publication number: 20130081036Abstract: A method, system, and computer-readable medium is described for facilitating interactions between task requesters who have tasks that are available to be performed and task performers who are available to perform tasks. In some situations, the tasks to be performed are human performance tasks that use cognitive and other mental skills of human task performers, such as to employ judgment, perception and/or reasoning skills of the human task performers. In addition, in some situations the available tasks are submitted by human task requesters via application programs that programmatically invoke one or more application program interfaces of an electronic marketplace in order to request that the tasks be performed and to receive corresponding results of task performance in a programmatic manner, so that an ensemble of unrelated human agents can interact with the electronic marketplace to collectively perform a wide variety and large number of tasks.Type: ApplicationFiled: September 14, 2012Publication date: March 28, 2013Applicant: AMAZON TECHNOLOGIES, INC.Inventors: Peter D. Cohen, Daniel A. Sanderson, Mikhail Seregine, Brett Kiefer, Jang Han Goo, Jeffrey P. Bezos