Abstract: A thermoacoustic imaging system and method for monitoring tissue temperature within a region of interest, which has an object of interest and a reference that are separated by at least one boundary. The system and method include a thermoacoustic imaging system with an adjustable radio frequency (RF) applicator configured to emit RF energy pulses into the tissue region of interest and heat tissue therein, an acoustic receiver configured to receive bipolar acoustic signals generated in response to heating of tissue in the region of interest, and one or more processors that process at least one received bipolar acoustic signal generated in the region of interest in response to the RF energy pulses to determine a peak-to-peak amplitude thereof and calculate a temperature at the at least one boundary using the peak-to-peak amplitude of the at least one bipolar acoustic signal.

Abstract: A method and system for estimating fractional fat content of an object of interest. The method and system include a thermoacoustic imaging system comprising an adjustable radio frequency (RF) applicator configured to emit RF energy pulses into the region of interest and heat tissue therein and an acoustic receiver configured to receive bipolar acoustic signals generated in response to heating of tissue in the region of interest; and one or more processors. The one or more processors are able to process bipolar acoustic signals received by the acoustic receiver in response to RF energy pulses emitted into the region of interest using the RF applicator to determine a setting for the RF applicator that yields bipolar acoustic signals with at least one enhanced metric thereof, determine an impedance of the RF applicator used to yield acoustic bipolar signals with the enhanced at least one metric, and estimate fractional fat content of the object of interest using the determined impedance.

Abstract: A method and system for reconstructing a thermoacoustic image that utilizes the steps of directing radio frequency (RF) energy pulses generated by an RF source into a tissue region of interest; detecting, at each of a plurality of views along a scanning trajectory of a transducer element array about the region of interest, acoustic signals generated within the region of interest in response to the RF energy pulses and generating thermoacoustic data; applying at least one correction kernel to the thermoacoustic data; and after the at least one correction kernel has been applied to the thermoacoustic data, reconstructing a thermoacoustic image therefrom.

Abstract: A method and system for enhancing radio frequency energy delivery to a tissue region of interest. The method and system direct with a radio frequency (RF) applicator, one or more RF energy pulses into the tissue region of interest, the tissue region of interest comprising an object of interest and at least one reference that are separated by at least one boundary; detect with an acoustic receiver, at least one bipolar acoustic signal generated in the tissue region of interest in response to the RF energy pulses and processing the at least one bipolar acoustic signal to determine a peak-to-peak amplitude thereof; adjust the RF applicator to maximize the peak-to-peak amplitude of bipolar acoustic signals generated in the tissue region of interest in response to RF energy pulses generated by the adjusted RF applicator; and direct with the adjusted RF applicator, one or more RF energy pulses into the region of interest.

Abstract: A system and method utilizing thermoacoustic imaging to estimating tissue temperature within a region of interest that includes an object of interest and a reference which are separated by at least one boundary located at least at two boundary locations. The system and method use a thermoacoustic imaging system that includes an adjustable radio frequency (RF) applicator configured to emit RF energy pulses into the tissue region of interest and heat tissue therein and an acoustic receiver configured to receive bipolar acoustic signals generated in response to heating of tissue in the region of interest; and one or more processors that are able to: process received bipolar acoustic generated in the region of interest in response to the RF energy pulses to determine a peak-to-peak amplitude thereof; and calculate a temperature at the at least two boundary locations using the peak-to-peak amplitudes of the bipolar acoustic signals and a distance between the boundary locations.

Abstract: A system comprises an ultrasound imaging system comprising at least one ultrasound transducer array, a thermoacoustic imaging system comprising at least one thermoacoustic transducer array mechanically connected to the at least one ultrasound transducer array such that a centerline of the at least one thermoacoustic transducer array is at a known angle with respect to a centerline of the at least one ultrasound transducer array, the at least one ultrasound transducer array moveable to orient the at least one thermoacoustic transducer array in at least one imaging position based on the known angle; and a processing unit configured to obtain thermoacoustic data of a region of interest at the at least one imaging position using the at least one thermoacoustic transducer array.

Abstract: A method of obtaining thermoacoustic data comprises obtaining ultrasound data of a region of interest using at least one ultrasound transducer array, the at least one ultrasound transducer array mechanically connected to at least one thermoacoustic transducer array such that a centerline of the at least one thermoacoustic transducer array is at a known angle with respect to a centerline of the at least one ultrasound transducer array, adjusting a position of the at least one ultrasound transducer array to orient the at least one thermoacoustic transducer array in at least one imaging position based on the known angle, and obtaining thermoacoustic data of the region of interest at the at least one imaging position using the at least one thermoacoustic transducer array.

Abstract: Described herein is a chimeric antigen receptor (CAR) platform with the ability to (a) serve as an ON/OFF switch (with the ability for tenability/titrability), (b) sense multiple antigens and perform logic computations, and/or (c) independently regulate multiple signaling pathways. The compositions provided herein permit the degree of control and discrimination necessary to optimize CAR T cell therapy. Also described herein are cells comprising such compositions and the use of these compositions and/or cells in the treatment of cancer.

Abstract: A system for estimating fractional fat content of an object of interest. An energy emitter is used to direct an energy signal toward the region of interest, wherein the region of interest has an object of interest, a reference with known properties, and a boundary area with one or more boundary locations between the object of interest and the reference. Next, a plurality of thermoacoustic or ultrasonic transducers is used to receive a plurality of thermoacoustic bipolar signals from the one or more boundary locations, wherein the thermoacoustic bipolar signals are induced by the energy signal. A machine configured to accept data from the energy emitter and the plurality of thermoacoustic or ultrasonic transducers and calculate a fat concentration that is a function of a difference between two peaks of the thermoacoustic bipolar signal at each respective boundary location and a distance or distances between each respective boundary location.

Abstract: A method and system for estimating fractional fat content of an object of interest. An energy emitter is used to direct an energy signal with an energy signal electric field strength toward the region of interest, wherein the region of interest has an object of interest, a reference, and a boundary between the object of interest and the reference. Next, a thermoacoustic or ultrasonic transducer is used to receive a thermoacoustic bipolar signal from the boundary, wherein the thermoacoustic bipolar signal is induced by the energy signal. Finally, a machine is used to accept data from the energy emitter and thermoacoustic or ultrasonic transducer, correlate the thermoacoustic bipolar signal to an electric field strength of the reference at the boundary to generate a corrected thermoacoustic bipolar signal at the boundary, and calculate a fat concentration of the object of interest as a function of the corrected thermoacoustic bipolar signal at the boundary.

Abstract: A method and system for estimating fractional fat content of an object of interest. An energy emitter is used to direct an energy signal toward the region of interest, wherein the region of interest has an object of interest, a reference, and a boundary area with one or more boundary locations between the object of interest and the reference. Next, a plurality of thermoacoustic or ultrasonic transducers is used to receive a plurality of thermoacoustic bipolar signals from the one or more boundary locations, wherein the thermoacoustic bipolar signals are induced by the energy signal. A machine configured to accept data from the energy emitter and the plurality of thermoacoustic or ultrasonic transducers and calculate a fat concentration that is a function of the thermoacoustic bipolar signal at each respective boundary location and the distance or distances between locations.

Abstract: A method for estimating fractional fat content of an object of interest is described. The method comprises obtaining thermoacoustic data of a region of interest containing an object of interest and a reference, and estimating fractional fat content of the object of interest using the thermoacoustic data and at least one parameter of the reference.

Abstract: A stacked semiconductor memory apparatus includes a memory module including a plurality of memory chips; and a logic circuit block with the memory module stacked thereon, configured to be electrically coupled with an interface substrate through a first terminal group and a second terminal group and to communicate with a controller, and to include a test circuit that receives a first test signal through the first terminal group from the controller and outputs the first test signal through the second terminal group in a test mode.

Abstract: A method is provided for iteratively reconstructing an image of an object. The method includes accessing measurement data associated with the image, and using a simultaneous algorithm to reconstruct the image. Using the simultaneous algorithm to reconstruct the image includes determining a scaling factor that is voxel-dependent, and applying the voxel-dependent scaling factor to a gradient of an objective function to reconstruct the image.

Abstract: A light emitting diode (LED) illumination device having a power compensation function is provided. The illumination device includes a light emitting unit including a plurality of LEDs connected in series, a rectifier for rectifying input AC power to provide a rectified voltage to the light emitting device, and a power compensator for detecting a change in the rectified voltage provided to the light emitting device and compensating a current provided to the light emitting device according to the detected change in the rectified voltage.

Abstract: A reproducing apparatus for automatically converting an output mode based on movements of a casing, and methods thereof. A reproducing apparatus having a first and a second casings includes an internal output unit outputting at least one of reproduced audio and video; an external output unit outputting at least one of the reproduced audio and video to an external device casing; a detector detecting movements of the second casing; and a control unit controlling such that at least one reproduced audio and video is outputted to at least one of the internal output unit and the external output unit. Accordingly, there is no need for a user to change the output mode, thereby reducing inconvenience for the user.

Abstract: A method is provided for iteratively reconstructing an image of an object. The method includes accessing measurement data associated with the image, and using a simultaneous algorithm to reconstruct the image. Using the simultaneous algorithm to reconstruct the image includes determining a scaling factor that is voxel-dependent, and applying the voxel-dependent scaling factor to a gradient of an objective function to reconstruct the image.

Abstract: A light emitting diode (LED) illumination device having a power compensation function is provided. The illumination device includes a light emitting unit including a plurality of LEDs connected in series, a rectifier for rectifying input AC power to provide a rectified voltage to the light emitting device, and a power compensator for detecting a change in the rectified voltage provided to the light emitting device and compensating a current provided to the light emitting device according to the detected change in the rectified voltage.

Abstract: A plasma display panel for adaptively reducing load effect and improving luminescence efficiency and discharge efficiency, and a driving method thereof. A plasma display panel includes a capacitive load; a source capacitor; a sustain voltage source to generate a sustain voltage; a first inductor formed on a first current path where a current flows from the capacitive load to the source capacitor; a second inductor formed on a second current path where a current flows from the source capacitor to the capacitive load; a switch configuration and switch control circuit that controls the switching operations of the switch configuration such that at least two discharges may occur during one sustain pulse cycle.

Abstract: A plasma display panel employs a voltage circuit having an input and an output, the voltage circuit configured for supplying a negative voltage for an electrode. The plasma display panel also employs a power supply that has a positive terminal and a negative terminal, where the negative terminal is connected to the input of the voltage circuit. The power supply is otherwise configured relative to the voltage circuit such that the voltage difference between the output and the input of the voltage circuit is fixed as a function of the power supply. By fixing this voltage difference, parasitic capacitance is minimized, power consumption and calorific value are reduced, and the plasma display panel operates in a more stable manner.