Patents by Inventor Janice G. Shigeura, legal representative
Janice G. Shigeura, legal representative has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8007733Abstract: An apparatus and methods are provided for heating and sensing the temperature of a chemical reaction chamber without direct physical contact between a heating device and the reaction chamber, or between a temperature sensor and the reaction chamber. A plurality of chemical reaction chambers can simultaneously or sequentially be heated independently and monitored separately.Type: GrantFiled: October 26, 2007Date of Patent: August 30, 2011Assignee: Applied Biosystems, LLCInventors: John Shigeura, Janice G. Shigeura, legal representative
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Patent number: 7978326Abstract: An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.Type: GrantFiled: December 3, 2009Date of Patent: July 12, 2011Assignee: Applied Biosystems, LLCInventors: Mark F. Oldham, Eric S. Nordman, Richard T. Reel, John S. Shigeura, Janice G. Shigeura, legal representative
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Patent number: 7636160Abstract: An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.Type: GrantFiled: January 26, 2009Date of Patent: December 22, 2009Assignee: Applied Biosystems, LLCInventors: Mark F. Oldham, Eric S. Nordman, Richard T. Reel, John S. Shigeura, Janice G. Shigeura, legal representative
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Patent number: 7636159Abstract: An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.Type: GrantFiled: September 17, 2008Date of Patent: December 22, 2009Assignee: Applied Biosystems, LLCInventors: Mark F. Oldham, Eric S. Nordman, Richard T. Reel, John S. Shigeura, Janice G. Shigeura, legal representative
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Patent number: 7585663Abstract: A device, system, and method are provided for thermally treating a fluid processing device. According to various embodiments, a system is provided that can include a thermal device and a fluid processing device holder. The thermal device can include a first block having a thermal conductivity greater than 0.5 Watt per centimeter Kelvin (W/cm·K), a second block having a thermal conductivity greater than 0.5 W/cm·K, and a heat-pump device disposed between the first block and the second block. The heat-pump device can transfer thermal energy from at least one of the first block and the second block to the other of the first block and the second block. The fluid processing device holder can hold a fluid processing device in a heat-transfer position with respect to the first block and the second block. The fluid processing device can be a microfluidic device.Type: GrantFiled: August 26, 2004Date of Patent: September 8, 2009Assignee: Applied Biosystems, LLCInventors: John S. Shigeura, Janice G. Shigeura, legal representative, Sean M. Desmond, David M. Cox
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Patent number: 7486396Abstract: Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the detection zone with radiation; a detector capable of collecting at least one charge corresponding to an emission beam emitted from the detection zone, the detector having an output; and a time delay integration system coupled to the detector for effecting time delay integration of the at least one charge by accumulating the at least one charge before reading the at least one charge at the output of the detector. Various embodiments provide an apparatus with a multi-notch filter. Various embodiments provide a solid state laser, a micro-wire laser, or an organic light-emitting diode as a irradiation source.Type: GrantFiled: August 22, 2007Date of Patent: February 3, 2009Assignee: Applera CorporationInventors: Mark F. Oldham, Eric S. Nordman, Richard T. Reel, Janice G. Shigeura, legal representative, John S. Shigeura
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Patent number: 7485085Abstract: The present application relates to an apparatus and method for heat transfer for thermal cycling.Type: GrantFiled: January 23, 2004Date of Patent: February 3, 2009Assignee: Applied Biosystems Inc.Inventors: Janice G. Shigeura, legal representative, John Shigeura
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Patent number: 7428047Abstract: An apparatus for detecting analytes in a sample is provided. The apparatus can include: a flow cytometry system including one or more detection zones; one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from detectable analytes in the one or more detection zones, which have been excited by the radiation, wherein at least one detector includes an output; a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector; and a sorting mechanism, for example, to effect flow cytometry. Methods for detecting analytes in a sample are also provided.Type: GrantFiled: December 22, 2006Date of Patent: September 23, 2008Assignee: Applied Biosystems Inc.Inventors: Mark F. Oldham, Eric S. Nordman, Richard T. Reel, Janice G. Shigeura, legal representative, John S. Shigeura
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Patent number: 7294812Abstract: An apparatus and methods are provided for heating and sensing the temperature of a chemical reaction chamber without direct physical contact between a heating device and the reaction chamber, or between a temperature sensor and the reaction chamber. A plurality of chemical reaction chambers can simultaneously or sequentially be heated independently and monitored separately.Type: GrantFiled: June 8, 2006Date of Patent: November 13, 2007Assignee: Applera CorporationInventors: Janice G. Shigeura, legal representative, John Shigeura, deceased
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Patent number: 7280207Abstract: An apparatus for detecting analytes in a sample is provided. The apparatus can include: a flow cytometry system including one or more detection zones; one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from detectable analytes in the one or more detection zones, which have been excited by the radiation, wherein at least one detector includes an output; a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector; and a sorting mechanism, for example, to effect flow cytometry. Methods for detecting analytes in a sample are also provided.Type: GrantFiled: July 8, 2004Date of Patent: October 9, 2007Assignee: Applera CorporationInventors: Mark F. Oldham, Eric S. Nordman, Richard T. Reel, Janice G. Shigeura, legal representative, John S. Shigeura, deceased
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Patent number: 7265833Abstract: Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the detection zone with radiation; a detector capable of collecting at least one charge corresponding to an emission beam emitted from the detection zone, the detector having an output; and a time delay integration system coupled to the detector for effecting time delay integration of the at least one charge by accumulating the at least one charge before reading the at least one charge at the output of the detector. Various embodiments provide an apparatus with a multi-notch filter. Various embodiments provide a solid state laser, a micro-wire laser, or an organic light-emitting diode as a irradiation source.Type: GrantFiled: July 8, 2004Date of Patent: September 4, 2007Assignee: Applera CorporationInventors: Mark F. Oldham, Eric S. Nordman, Richard T. Reel, Janice G. Shigeura, legal representative, John S. Shigeura, deceased
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Patent number: 7235163Abstract: Apparatus and method for loading a channel device for electrophoretic separation including cilia which can be deflected into wells of a multi-well tray.Type: GrantFiled: September 12, 2003Date of Patent: June 26, 2007Assignee: Applera CorporationInventors: Paul O. Ramstad, Sean M. Desmond, Janice G. Shigeura, legal representative, Richard T. Reel, Richard Morris, John Shigeura, deceased
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Patent number: 7173218Abstract: An apparatus and methods are provided for heating and sensing the temperature of a chemical reaction chamber without direct physical contact between a heating device and the reaction chamber, or between a temperature sensor and the reaction chamber. A plurality of chemical reaction chambers can simultaneously or sequentially be heated independently and monitored separately.Type: GrantFiled: December 7, 2004Date of Patent: February 6, 2007Assignee: Applera CorporationInventors: Janice G. Shigeura, legal representative, John Shigeura, deceased