Patents by Inventor Janice M. Nigro

Janice M. Nigro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting loss of wild-type p53
    Patent number: 7267955
    Abstract: Methods are provided for restoring wild-type p53 gene function to a cell. Such methods include gene therapy. Typically, this will stop tumor cells from proliferating.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: September 11, 2007
    Assignee: The Johns Hopkins University
    Inventors: Bert Vogelstein, Suzanne Baker, Eric R. Fearon, Janice M. Nigro
  • Methods for restoring wild-type p53 gene function
    Patent number: 6800617
    Abstract: Methods are provided for restoring wild-type p53 gene function to a cell. Such methods include gene therapy. Typically, this will stop tumor cells from proliferating.
    Type: Grant
    Filed: March 22, 1993
    Date of Patent: October 5, 2004
    Assignee: The Johns Hopkins University
    Inventors: Bert Vogelstein, Suzanne Baker, Eric R. Fearon, Janice M. Nigro
  • Methods for restoring wild-type p53 gene function
    Patent number: 6677312
    Abstract: Methods are provided for restoring wild-type p53 gene function to a cell. Such methods include gene therapy. Typically, this will stop tumor cells from proliferating.
    Type: Grant
    Filed: April 3, 1997
    Date of Patent: January 13, 2004
    Assignee: The Johns Hopkins University
    Inventors: Bert Vogelstein, Suzanne Baker, Eric R. Fearon, Janice M. Nigro
  • Diagnostic method detecting loss of wild-type p53
    Patent number: 6090566
    Abstract: Methods and kits are provided for assessing mutations and/or loss of the p53 gene in human tumors. Both deletion mutations and point mutations in p53 are observed in the same human tumor cells and these mutations are clonal within the cells of the tumor. Loss of wild-type p53 genes is responsible for neoplastic progression.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: July 18, 2000
    Assignee: Johns Hopkins University
    Inventors: Bert Vogelstein, Suzanne J. Baker, Eric R. Fearon, Janice M. Nigro
  • Detection of loss of the wild-type P53 gene and kits therefor
    Patent number: 5527676
    Abstract: Methods and kits are provided for assessing mutations and/or loss of the p53 gene in human tumors. Both deletion mutations and point mutations in p53 are observed in the same human tumor cells and these mutations are clonal within the cells of the tumor. Loss of wild-type p53 genes is responsible for neoplastic progression.
    Type: Grant
    Filed: March 22, 1993
    Date of Patent: June 18, 1996
    Assignee: The Johns Hopkins University
    Inventors: Bert Vogelstein, Suzanne J. Baker, Eric R. Fearon, Janice M. Nigro