Patents by Inventor Janice M Paterson

Janice M Paterson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human adenylate cyclase and use therefor
    Publication number: 20020142436
    Abstract: There is provided a novel adenylate cyclase enzyme, the nucleotide sequence of which is set out in SEQ ID NO: 98. The activity of the adenylate cyclase is uniquely regulated by calcineurin, a protein phosphatase. The calcineurin binding site has been identified at amino acids 503 to 610 of the novel adenylate cyclase.
    Type: Application
    Filed: December 28, 2000
    Publication date: October 3, 2002
    Inventors: Ferenc Antoni, Janice M. Paterson
  • Human adenylate cyclase and use therefor
    Patent number: 6197581
    Abstract: There is provided a novel adenylate cyclase enzyme, the nucleotide sequence of which is set out in SEQ ID NO: 98. The activity of the adenylate cyclase is uniquely regulated by calcineurin, a protein phosphatase. The calcineurin binding site has been identified at amino acids 503 to 610 of the novel adenylate cyclase. Regulation of the novel adenylate cycalse may be useful in treating certain disorders. Suitable regulators include agents which bind to the 503-610 amino acid site and include calcineurin, its activators, inhibitors and competitors and antibodies specific to that site. Specific disorders include neurological disorders such as Parkinsons' disease, cardiovascular disorders such as angina pectoris and tumors, especially ovarian tumors.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: March 6, 2001
    Assignee: Medical Research Council
    Inventors: Ferenc Antoni, Janice M Paterson