Patents by Inventor Janine D. North

Janine D. North has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING HEAVY MENSTRUAL BLEEDING
    Publication number: 20230285396
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: May 15, 2023
    Publication date: September 14, 2023
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • Methods of Treating Heavy Menstrual Bleeding
    Publication number: 20230277556
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: May 15, 2023
    Publication date: September 7, 2023
    Inventors: Kristof Chwalisz, Jane Castelli-Haley, Oscar Antunez Flores, Keith Gordon, Rita Jain, Juki Wing-Keung Ng, Janine D. North, Charlotte D. Owens, Hannah Palac, Paul M. Peloso, Michael C. Snabes, Ahmed M. Soliman, James W. Thomas, Mohamad Shebley
  • PHARMACEUTICAL FORMULATIONS FOR TREATING ENDOMETRIOSIS, UTERINE FIBROIDS, POLYCYSTIC OVARY SYNDROME OR ADENOMYOSIS
    Publication number: 20230255968
    Abstract: The present disclosure relates to pharmaceutical compositions comprising a gonadotropin-releasing hormone (GnRH) antagonist and methods of preparing and using such compositions. The disclosure also relates to methods of facilitating release of a GnRH antagonist from a pharmaceutical composition.
    Type: Application
    Filed: February 13, 2023
    Publication date: August 17, 2023
    Inventors: Jayanthy Jayanth, Kevin C. Spence, Gregory A. McClelland, Anna V. Stepanenko, Kristof Chwalisz, Charlotte D. Owens, James W. Thomas, Jane Castelli-Haley, Keith Gordon, Michael C. Snabes, Ahmed M. Soliman, Geoff Zhang, David Metzger, Yanxia Li, Tzuchi R. Ju, Xi Shao, Oscar Antunez Flores, Rita Jain, Juki Wing-Keung Ng, Janine D. North, Hannah Palac, Paul M. Peloso
  • Methods of treating heavy menstrual bleeding
    Patent number: 11707464
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Grant
    Filed: November 18, 2021
    Date of Patent: July 25, 2023
    Assignee: AbbVie Inc.
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • Methods of treating heavy menstrual bleeding
    Patent number: 11344551
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: May 31, 2022
    Assignee: AbbVie Inc.
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • METHODS OF TREATING HEAVY MENSTRUAL BLEEDING
    Publication number: 20220079945
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: November 18, 2021
    Publication date: March 17, 2022
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • METHODS OF TREATING HEAVY MENSTRUAL BLEEDING
    Publication number: 20210275528
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: May 20, 2021
    Publication date: September 9, 2021
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • Methods of treating heavy menstrual bleeding
    Patent number: 11045470
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: June 29, 2021
    Assignee: ABBVIE INC.
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • Methods of Treating Heavy Menstrual Bleeding
    Publication number: 20210154207
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: July 23, 2018
    Publication date: May 27, 2021
    Applicant: AbbVie Inc.
    Inventors: Kristof Chwalisz, Jane Castelli-Haley, Oscar Antunez Flores, Keith Gordon, Rita Jain, Juki Wing-Keung Ng, Janine D. North, Charlotte D. Owens, Hannah Palac, Paul M. Peloso, Michael C. Snabes, Ahmed M. Soliman, James W. Thomas
  • Methods of treating heavy menstrual bleeding
    Patent number: 10881659
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: January 5, 2021
    Assignee: ABBVIE INC.
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • METHODS OF TREATING HEAVY MENSTRUAL BLEEDING
    Publication number: 20200163965
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: January 29, 2020
    Publication date: May 28, 2020
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • METHODS OF TREATING HEAVY MENSTRUAL BLEEDING
    Publication number: 20190209563
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: March 15, 2019
    Publication date: July 11, 2019
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • METHODS OF TREATING HEAVY MENSTRUAL BLEEDING
    Publication number: 20190209562
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: March 15, 2019
    Publication date: July 11, 2019
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Juki Wing-Keung Ng
  • Solid Pharmaceutical Formulations for Treating Endometriosis, Uterine Fibroids, Polycystic Ovary Syndrome or Adenomyosis
    Publication number: 20190054027
    Abstract: The present disclosure relates to pharmaceutical compositions comprising a gonadotropin-releasing hormone (GnRH) antagonist and methods of preparing and using such compositions. The disclosure also relates to methods of facilitating release of a GnRH antagonist from a pharmaceutical composition.
    Type: Application
    Filed: August 20, 2018
    Publication date: February 21, 2019
    Applicant: AbbVie Inc.
    Inventors: Yihong Qiu, Yuchuan Gong, Alexander Ruggles, Jared A. Baird, Kristof Chwalisz, Charlotte D. Owens, James W. Thomas, Jane Castelli-Haley, Keith Gordon, Michael C. Snabes, Ahmed M. Soliman, Oscar Antunez Flores, Rita Jain, Juki Wing-Keung Ng, Janine D. North, Hannah Palac, Paul M. Peloso, Laura A. Williams, Hui Zu, Yuerong Hu
  • Pharmaceutical Formulations for Treating Endometriosis, Uterine Fibroids, Polycystic Ovary Syndrome or Adenomyosis
    Publication number: 20190054088
    Abstract: The present disclosure relates to pharmaceutical compositions comprising a gonadotropin-releasing hormone (GnRH) antagonist and methods of preparing and using such compositions. The disclosure also relates to methods of facilitating release of a GnRH antagonist from a pharmaceutical composition.
    Type: Application
    Filed: August 20, 2018
    Publication date: February 21, 2019
    Applicants: AbbVie Inc., Neurocrine Biosciences, Inc.
    Inventors: Jayanthy Jayanth, Kevin C. Spence, Gregory A. McClelland, Anna V. Stepanenko, Kristof Chwalisz, Charlotte D. Owens, James W. Thomas, Jane Castelli-Haley, Keith Gordon, Michael C. Snabes, Ahmed M. Soliman, Geoff Zhang, David Metzger, Yanxia Li, Tzuchi R. Ju, Xi Shao, Oscar Antunez Flores, Rita Jain, Juki Wing-Keung Ng, Janine D. North, Hannah Palac, Paul M. Peloso, Laura A. Williams
  • METHODS OF TREATING HEAVY MENSTRUAL BLEEDING
    Publication number: 20140288031
    Abstract: The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 25, 2014
    Inventors: Kristof Chwalisz, Laura A. Williams, Rita I. Jain, Janine D. North, Wing-Keung Juki K. Ng