Patents by Inventor Janine E. Sabo

Janine E. Sabo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In situ nicotinamide coenzyme generating system for enzyme based clinical chemistry assays
    Patent number: 5589348
    Abstract: The invention relates to an improved enzymatic method for determining the concentration of an analyte in a sample body fluid. The improvement comprises a coupled enzyme reaction scheme comprising the in situ generation of reduced nicotinamide coenzyme, with either simultaneous or subsequent re-oxidation of coenzyme by an analyte substrate and substrate specific enzymes. The change in absorbance due to the reoxidation of coenzyme is proportional to the concentration of analyte in the reaction mixture.
    Type: Grant
    Filed: March 22, 1994
    Date of Patent: December 31, 1996
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Richard A. Kaufman, John M. Konopka, Henry J. Rosenfeld, Janine E. Sabo