Abstract: A liquid-based metering device includes: at least one dispensing tip, a non-positive displacement and bi-directional pump for dispensing a liquid, a differential pressure flow sensing device including two pressure sensors, a control circuit for driving the pump and the dispensing operation, wherein the pressure sensors of the differential pressure flow sensing device are facing a substrate and are mounted on the substrate, and the substrate includes the electrical connections for the connection of the pressure sensors, the pressure sensors including membranes which are facing the liquid and the control circuit being connected to the pump and to the substrate.

Abstract: The present invention relates to a device (1) for calibrating a pipette or a dispensing system comprising a plate (2), said plate (2) comprising at least one channel (3) with a loading port (4) for receiving a test volume of a fluid at one end of the at least one channel and an opening (5) at the other end of the at least one channel, wherein the at least one channel (3) is constructed as a capillary.

Abstract: The present invention discloses a pressure measurement device comprising: a substrate that includes at least one pressure sensing module and at least one fluid-conductive channel, wherein each channel has a first aperture and a second aperture. The substrate is flexible such that the pressure measurement device is conformably adjustable onto an object's surface. The first aperture is located on the substrate such that when the substrate is suitably adjusted onto the object's surface, the first aperture is open to the exterior of the object's surface. The pressure sensors module is operatively connected to at least one of the second apertures, such that the at least one pressure sensing module is generally being subjected to the pressure being present at the first aperture.

Abstract: The present invention discloses a pressure measurement device comprising: a substrate that includes at least one pressure sensing module and at least one fluid-conductive channel, wherein each channel has a first aperture and a second aperture. The substrate is flexible such that the pressure measurement device is conformably adjustable onto an object's surface. The first aperture is located on the substrate such that when the substrate is suitably adjusted onto the object's surface, the first aperture is open to the exterior of the object's surface. The pressure sensors module is operatively connected to at least one of the second apertures, such that the at least one pressure sensing module is generally being subjected to the pressure being present at the first aperture.

Abstract: The present invention relates to a device (1) for calibrating a pipette or a dispensing system comprising a plate (2), said plate (2) comprising at least one channel (3) with a loading port (4) for receiving a test volume of a fluid at one end of the at least one channel and an opening (5) at the other end of the at least one channel, wherein the at least one channel (3) is constructed as a capillary.

Abstract: A fluidic system for analysing biomolecules in solution comprises a microchannel (21) having a inlet port (22) and an outlet port (23) across which extends a set of interdigitated electrodes (24) to which an AC voltage source having a voltage of 0-20V and a frequency of 100 Hz to 20 MHz. A fluid flow (25) through the microchannel (21) carries functionalised microbeads (26) and by applying the appropriate AC voltage and frequency to the electrodes (24) the microbeads (26) can be retained at the site of the electrodes (24) to form a packed bed (27). The packed bed (27) of microbeads is then subsequently perfused with a sample containing the analyte (28) specifically bound by the ligand immobilised on the microbeads. The analyte is separated and concentrated by the packed microbeads and can be detected directly or indirectly by further perfusion of labelled reagent molecules.