Patents by Inventor Janne Jensen

Janne Jensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Differentiation of human pluripotent stem cells into cells expressing mature hepatocyte markers by 2D and bioreactor culture
    Patent number: 9284531
    Abstract: The present invention relates to the use of 3D culturing systems for the derivation of hepatocyte-like cells from human pluripotent stem cells (hPS). In particular, the invention concerns the directed differentiation and maturation of human pluripotent stem cells into hepatocyte like cells in 3D hollow fiber capillary bioreactors.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: March 15, 2016
    Assignee: Takara Bio Europe AB
    Inventors: Harald Stachelscheid, Katrin Zeilinger, Janne Jensen, Thomas Urbaniak
  • 3-dimensional scaffolds for improved differentiation of pluripotent stem cells to hepatocytes
    Patent number: 9127255
    Abstract: The present invention relates to the use of 3-dimensional (3D) synthetic or animal-derived bioscaffolds as substrates for the improved growth and differentiation of hPS (Human pluripotent stem cells); these scaffolds being adapted for use in conjunction with existing cell culture lab plastic-ware. More specifically, it relates to the seeding of these scaffolds, either alone or in conjunction with various biologic matrix coatings, with hPS cells for the improved differentiation of said hPS cells into hepatocyte or hepatocyte-like cell types. The invention also relates to the seeding of partially-differentiated hepatocyte progenitors onto scaffolds for further differentiation into more mature hepatocyte-cell types.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: September 8, 2015
    Assignee: Takara Bio Europe AB
    Inventor: Janne Jensen
  • 3-DIMENSIONAL SCAFFOLDS FOR IMPROVED DIFFERENTIATION OF PLURIPOTENT STEM CELLS TO HEPATOCYTES
    Publication number: 20130336933
    Abstract: The present invention relates to the use of 3-dimensional (3D) synthetic or animal-derived bioscaffolds as substrates for the improved growth and differentiation of hPS (Human pluripotent stem cells); these scaffolds being adapted for use in conjunction with existing cell culture lab plastic-ware. More specifically, it relates to the seeding of these scaffolds, either alone or in conjunction with various biologic matrix coatings, with hPS cells for the improved differentiation of said hPS cells into hepatocyte or hepatocyte-like cell types. The invention also relates to the seeding of partially-differentiated hepatocyte progenitors onto scaffolds for further differentiation into more mature hepatocyte-cell types.
    Type: Application
    Filed: June 14, 2011
    Publication date: December 19, 2013
    Applicant: Cellartis AB
    Inventor: Janne Jensen
  • 3-DIMENSIONAL SCAFFOLDS FOR IMPROVED DIFFERENTIATION OF PLURIPOTENT STEM CELLS TO HEPATOCYTES
    Publication number: 20130164266
    Abstract: The present invention relates to the use of 3-dimensional (3D) synthetic or animal-derived bioscaffolds as substrates for the improved growth and differentiation of hPS (Human pluripotent stem cells); these scaffolds being adapted for use in conjunction with existing cell culture lab plastic-ware. More specifically, it relates to the seeding of these scaffolds, either alone or in conjunction with various biologic matrix coatings, with hPS cells for the improved differentiation of said hPS cells into hepatocyte or hepatocyte-like cell types. The invention also relates to the seeding of partially-differentiated hepatocyte progenitors onto scaffolds for further differentiation into more mature hepatocyte-cell types.
    Type: Application
    Filed: June 14, 2011
    Publication date: June 27, 2013
    Applicant: Cellartis AB
    Inventor: Janne Jensen
  • 3D CULTURING SYSTEMS FOR GROWTH AND DIFFERENTIATION OF HUMAN PLURIPOTENT STEM (hPS) CELLS
    Publication number: 20120115226
    Abstract: The present invention relates to the use of 3D culturing systems for the derivation of hepatocyte-like cells from human pluripotent stem cells (hPS). In particular, the invention concerns the directed differentiation and maturation of human pluripotent stem cells into hepatocyte like cells in 3D hollow fiber capillary bioreactors.
    Type: Application
    Filed: June 18, 2010
    Publication date: May 10, 2012
    Applicant: CELLARTIS AB
    Inventors: Harald Stachelsheid, Katrin Zeilinger, Janne Jensen, Thomas Urbaniak