Patents by Inventor Jaou-Chen Huang

Jaou-Chen Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peroxisome proliferator-activator receptor ? (PPAR?) and the development of preimplantation embryos
    Patent number: 8632452
    Abstract: Methods and compositions for enhancing development of a preimplantation mammalian embryo and for increasing the live birth potential of an in vitro fertilized mammalian embryo are disclosed. An in vitro method of activating the peroxisome proliferator activated receptor ? (PPAR?) in a preimplantation mammalian embryo comprises culturing an embryo in an embryo culture medium, and upon or after commencement of expression of PPAR? in the cells of the embryo, activating the PPAR? by adding an amount of a PPAR? ligand to said medium effective to bind to PPAR? to deter apoptosis in the cells of the cultured embryo and/or increase proliferation of the cells of the cultured embryo.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: January 21, 2014
    Assignee: Board of Regents of the University of Texas System
    Inventors: Jaou-Chen Huang, Alfred W-S Wun, Jennifer S. Goldsby, Kenneth Wu
  • Enhancement of mammalian embryo development
    Patent number: 7709259
    Abstract: A method of enhancing in vitro development of a mammalian embryo is disclosed which comprises supplementing the culture medium with a prostaglandin, or a prostaglandin analog, in an amount effective to promote complete hatching of the embryo (i.e., freeing of the embryo from the zona pellucida). The quality of human blastocysts is enhanced in vitro by culturing with a prostacyclin agonist, Iloprost. The in vivo implantation potential and live birth potential of an in vitro fertilization embryo is thereby enhanced and establishment of a viable pregnancy is facilitated.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: May 4, 2010
    Assignee: Board of Regents of the University of Texas System
    Inventors: Jaou-Chen Huang, Jennifer S. Goldsby, Wan-Song A. Wun
  • PEROXISOME PROLIFERATOR-ACTIVATOR RECEPTOR DELTA (PPARDELTA) AND THE DEVELOPMENT OF PREIMPLANTATION EMBRYOS
    Publication number: 20090156890
    Abstract: Methods and compositions for enhancing development of a preimplantation mammalian embryo and for increasing the live birth potential of an in vitro fertilized mammalian embryo are disclosed. An in vitro method of activating the peroxisome proliferator activated receptor ? (PPAR?) in a preimplantation mammalian embryo comprises culturing an embryo in an embryo culture medium, and upon or after commencement of expression of PPAR? in the cells of the embryo, activating the PPAR? by adding an amount of a PPAR? ligand to said medium effective to bind to PPAR? to deter apoptosis in the cells of the cultured embryo and/or increase proliferation of the cells of the cultured embryo.
    Type: Application
    Filed: October 12, 2006
    Publication date: June 18, 2009
    Inventors: Jaou-Chen Huang, Alfred W-S Wun, Jennifer Goldsby, Kenneth K. Wu
  • Enhancement of mammalian embryo development
    Publication number: 20090011496
    Abstract: A method of enhancing in vitro development of a mammalian embryo is disclosed which comprises supplementing the culture medium with a prostaglandin, or a prostaglandin analog, in an amount effective to promote complete hatching of the embryo (i.e., freeing of the embryo from the zona pellucida). The quality of human blastocysts is enhanced in vitro by culturing with a prostacyclin agonist, Iloprost. The in vivo implantation potential and live birth potential of an in vitro fertilization embryo is thereby enhanced and establishment of a viable pregnancy is facilitated.
    Type: Application
    Filed: March 7, 2006
    Publication date: January 8, 2009
    Inventors: Jaou-Chen Huang, Jennifer Goldsby, Wan-Song Wun
  • Enhancement of mammalian embryo development
    Publication number: 20060160213
    Abstract: A method of enhancing in vitro development of a mammalian embryo is disclosed which comprises supplementing the culture medium with a prostaglandin, or a prostaglandin analog, in an amount effective to promote complete hatching of the embryo (i.e., freeing of the embryo from the zona pellucida). The quality of human blastocysts is enhanced in vitro by culturing with a prostacyclin agonist, Iloprost. The in vivo implantation potential and live birth potential of an in vitro fertilization embryo is thereby enhanced and establishment of a viable pregnancy is facilitated.
    Type: Application
    Filed: March 7, 2006
    Publication date: July 20, 2006
    Inventors: Jaou-Chen Huang, Jennifer Goldsby, Wan-Song Wun