Abstract: A molecular filtration device and method of use capable of filtering and purifying molecules of a particular characteristic, wherein the amount of molecule to be filtered may be in the nanogram range and may be dispersed in a relatively large volume of solution. The resultant elution may include a relatively high concentration of desired molecule, due to a relatively small volume.

Abstract: A frit comprising a plurality of grooves; a drain hole; a transverse crossing lane; wherein said plurality of grooves are substantially parallel to one another and extend longitudinally across said frit; wherein said plurality of grooves comprise at least two different lengths; wherein said transverse crossing lane is substantially perpendicular to said plurality of grooves; wherein said drain hole is located within said transverse crossing lane; wherein said drain hole is located at a center of said transverse crossing lane.

Abstract: A consumable device comprising a substantially rigid two-layer main body, window for receiving a membrane, and an electronic tag for storing and communicating information, wherein the consumable device is configured to be received by a molecular filtration device for the purpose of creating a channel within which a solution may be inserted to purify molecules or exchange a buffer solution.

Abstract: A molecular filtration device and method of use capable of filtering and purifying molecules of a particular characteristic, wherein the amount of molecule to be filtered may be in the nanogram range and may be dispersed in a relatively large volume of solution. The resultant elution may include a relatively high concentration of desired molecule, due to a relatively small volume.

Abstract: A frit comprising a plurality of grooves; a drain hole; a transverse crossing lane; wherein said plurality of grooves are substantially parallel to one another and extend longitudinally across said frit; wherein said plurality of grooves comprise at least two different lengths; wherein said transverse crossing lane is substantially perpendicular to said plurality of grooves; wherein said drain hole is located within said transverse crossing lane; wherein said drain hole is located at a center of said transverse crossing lane.

Abstract: A molecular filtration device and method of use capable of filtering and purifying molecules of a particular characteristic, wherein the amount of molecule to be filtered may be in the nanogram range and may be dispersed in a relatively large volume of solution. The resultant elution may include a substantially pure solution comprising the desired molecule.

Abstract: A molecular filtration device and method of use capable of filtering and purifying molecules of a particular characteristic, wherein the amount of molecule to be filtered may be in the nanogram range and may be dispersed in a relatively large volume of solution. The resultant elution may include a substantially pure solution comprising the desired molecule.

Abstract: The methods described herein generally relate to characterization of large analytes, such as biomolecules, by molecular mass analysis. Specifically, the methods are directed to molecular mass analysis of singly- or multiply-charged ions by selective ion filtering carried out by a digital thresholding process.

Abstract: The present disclosure is related to improved systems and methods for delivering samples for high-throughput mass spectrometric analysis to an atmospheric-pressure ionization source. In an exemplary embodiment, the system includes a solvent reservoir for storing a solvent solution, a first valve which is coupled to the solvent reservoir, first and second pumps for delivering solvent solution and which are coupled to the first valve and which the delivery flow rate of the first pump is greater than the delivery flow rate of the second pump, an injection system having a sample injector and an second valve which is coupled to the first valve and which is capable of being coupled to can be couple to an electrospray ionization source. In another embodiment, the system can also include an atmospheric-pressure ionization chamber, an atmospheric-pressure ionization sprayer and a nebulizer gas source and a voltage supply source.