Abstract: The disclosure includes a catheter system comprising an inner catheter and an outer catheter configured to at least partially receive the inner catheter. Each of the inner catheter and the outer catheter may comprise an outer surface and an inner surface, wherein each of the outer and inner surfaces may be coated in a hydrophilic coating. In some embodiments, the hydrophilic coating is configured to reduce surface tension and increase lubricity of the inner catheter and the outer catheter.

Abstract: A guidewire is disclosed that includes a multi-edge profile configured to improve torque transmission and reduce frictional engagement during intravascular navigation. In some embodiments, the multi-edge profile includes a square cross-section twisted into a helical structure. In some embodiments, the helical configuration creates discrete peaks and valleys that minimize contact area with surrounding anatomical structures and catheter lumens, enhancing trackability and directional control. The guidewire may include variable pitch sections, polymer jackets, and hydrophilic coatings to further improve lubricity. In some embodiments, a method includes using the guidewire in combination with one or more catheters having textured inner surfaces to synergistically reduce drag and facilitate navigation through tortuous anatomy. In some embodiments, the system includes a diagnostic catheter that can be delivered to a tortuous pathway simultaneously with the catheter without the need for additional support catheters.

Abstract: The present invention relates to a method for coating the lumen of a tube using fluid displacement techniques. In some embodiments, the method involves introducing a first coating solution into the lumen of the tube using a positive or negative displacement, draining the excess solution to leave a film on the inner surface, and curing the film to form a uniform coating. In some embodiments, the displacement system can include a piston pump, peristaltic pump, and/or syringe. In some embodiments, a first coating solution may comprise a mixture of polyaziridine and either polyurethane or polyacrylate, while a second coating solution may comprise polysaccharide and/or polyacrylic acid and may be hydrophilic. Additional steps may include applying multiple layers, coating both the inner and outer surfaces of the tube, and/or using gas to drain the coating solution. In some embodiments, multiple tubes can be coated simultaneously using a manifold assembly.

Abstract: A pumping top may include a left panel and a right panel, each of the left panel and the right panel having a bottom edge and being configured to cover a side of a wearer's torso and cover and support a breast of the wearer. Each of the left panel and the right panel may include (i) an expandable bladder configured to contact and partially surround a corresponding breast of the wearer, (ii) a supply line coupled at one end to the bladder and at an opposite end to a connector disposed proximate the bottom edge, and (iii) a return line coupled at one end to the bladder and at an opposite end to the connector. The connector may be configured to couple to a circulating pump that is separate and distinct from the pumping top, which circulates warmed liquid through the pumping top.

Abstract: A pumping top may include a left panel and a right panel, each of the left panel and the right panel having a bottom edge and being configured to cover a side of a wearer's torso and cover and support a breast of the wearer. Each of the left panel and the right panel may include (i) an expandable bladder configured to contact and partially surround a corresponding breast of the wearer, (ii) a supply line coupled at one end to the bladder and at an opposite end to a connector disposed proximate the bottom edge, and (iii) a return line coupled at one end to the bladder and at an opposite end to the connector. The connector may be configured to couple to a circulating pump that is separate and distinct from the pumping top, which circulates warmed liquid through the pumping top.

Abstract: The disclosure is directed to a catheter system comprising an inner catheter and/or an outer catheter configured to at least partially receive the inner catheter. In some embodiments, the inner catheter comprises a proximal hub, a distal portion, and/or a pusher wire extending between the proximal hub and the distal portion. In some embodiments, the inner and/or the outer catheter does not include a smooth inner surface. In some embodiments, the inner and/or outer catheter includes an inner surface comprising a series of recessed surfaces. In some embodiments, the recessed surfaces are formed by the spaces between the catheter's reinforcement structure, where the spaces are filled and/or sealed by an encasement sleeve. In some embodiments, the reinforcement structure forms support surfaces for structures traversing through the inner diameter. In some embodiments, at least a portion of the support surfaces and/or recessed surfaces include reflown polymer and/or a hydrophilic coating.

Abstract: A pumping top may include a left panel and a right panel, each of the left panel and the right panel having a bottom edge and being configured to cover a side of a wearer's torso and cover and support a breast of the wearer. Each of the left panel and the right panel may include (i) an expandable bladder configured to contact and partially surround a corresponding breast of the wearer, (ii) a supply line coupled at one end to the bladder and at an opposite end to a connector disposed proximate the bottom edge, and (iii) a return line coupled at one end to the bladder and at an opposite end to the connector. The connector may be configured to couple to a circulating pump that is separate and distinct from the pumping top, which circulates warmed liquid through the pumping top.

Abstract: The disclosure includes a catheter system comprising an inner catheter and an outer catheter configured to at least partially receive the inner catheter. In some embodiments, the inner catheter comprises a proximal hub, a distal portion, and a pusher wire extending between the proximal hub and the distal portion. The distal portion of the inner catheter may comprise a hypotube. In some embodiments, the inner surface of the hypotube is coated with a lubricious coating.

Abstract: The disclosure includes a catheter comprising a proximal end, a distal end located opposite the proximal end, an outer surface extending between the proximal end and the distal end, and an inner surface located opposite the outer surface, wherein the inner surface is configured to also extend between the proximal end and the distal end. In some embodiments, each of the outer and inner surfaces is coated in a hydrophilic coating. The hydrophilic coating may be configured to reduce surface tension and increase the lubricity of the catheter.

Abstract: The disclosure includes a catheter system comprising an inner catheter and an outer catheter configured to at least partially receive the inner catheter. Each of the inner catheter and the outer catheter may comprise an outer surface and an inner surface, wherein each of the outer and inner surfaces may be coated in a hydrophilic coating. In some embodiments, the hydrophilic coating is configured to reduce surface tension and increase lubricity of the inner catheter and the outer catheter.