Abstract: Methods and systems of optimizing battery charging are disclosed. Battery state sensors are used to determine anode overpotential of a battery multiple times during multiple charge cycles. In a first phase, a reinforcement learning model (e.g., actor-critic model) is trained with rewards given throughout each charge cycle of the battery to optimize training. The reinforcement learning model can determine state-of-health characteristics of the battery over the charge cycles, and in a second phase, the reinforcement learning model is augmented accordingly. During this augmentation, the reinforcement learning model is trained with rewards given on a charge cycle-by-cycle basis, wherein rewards are given after looking at the charging optimization after the conclusion of each charge cycle.

Abstract: A malleable polysaccharide soft tissue filler for filling tissue cavities or voids such as those resulting from tumor removal or other tissue resection. The soft tissue filler includes a first cross-linking polysaccharide, preferably a beta-D glucan, and a second cross-linking polysaccharide. The soft tissue filler is both porous and malleable and can be formed to accommodate the tissue cavity or void. The soft tissue filler can include an embedded marker for locating on medical imaging. Methods of making the soft tissue filler including lyophilizing an aqueous polysaccharide suspension are disclosed. The second cross-linking polysaccharide provides for increased structural integrity in a high-porosity and malleable soft tissue filler in which the respective cross-linking polysaccharides synergistically provide structural scaffolding for one another. Methods of use are also disclosed.

Abstract: A malleable polysaccharide soft tissue filler for filling tissue cavities or voids such as those resulting from tumor removal or other tissue resection. The soft tissue filler includes a first cross-linking polysaccharide, preferably a beta-D glucan and a second cross-linking polysaccharide. The soft tissue filler is both porous and malleable and can be formed to accommodate the tissue cavity or void. The soft tissue filler can include an embedded marker for locating on medical imaging. Methods of making the soft tissue filler including lyophilizing an aqueous polysaccharide suspension are disclosed. The second cross-linking polysaccharide provides for increased structural integrity in a high-porosity and malleable soft tissue filler in which the respective cross-linking polysaccharides synergistically provide structural scaffolding for one another. Methods of use are also disclosed.

Abstract: The invention relates to an improved method for the preparation of 11(12)-pentadecen-15-olides.

Abstract: The invention relates to an improved method for the preparation of 11(12)-pentadecen-15-olides.