Patents by Inventor Jared Silverman

Jared Silverman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF
    Publication number: 20160213702
    Abstract: Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e.g. for the modulation of human gastrointestinal microbiota and to treat dysbioses.
    Type: Application
    Filed: February 5, 2016
    Publication date: July 28, 2016
    Applicant: KALEIDO BIOSCIENCES, INC.
    Inventors: Geoffrey A. von Maltzahn, Jared Silverman, Yvonne J. Yamanaka, John Miles Milwid, John M. Geremia
  • Daptomycin for the treatment of biofilm and catheter salvage
    Patent number: 8003673
    Abstract: Daptomycin can be used for biofilm treatment (particularly central venous catheter salvage for S. epidermidis infected catheters). Catheter salvage with daptomycin shows rapid cidality, activity against stationary phase bacteria, and penetration and activity in biofilms. The present inventions provide formulations, methods, and articles of manufacture useful for biofilm treatment or catheter salvage involving daptomycin. Particular formulations include daptomycin in lactated Ringer's solution having a rapid kill curve against the bacteria of the biofilm.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: August 23, 2011
    Assignee: Cubist Pharmaceuticals, Inc.
    Inventors: Jeffrey Alder, Jared Silverman, Lawrence Mortin, Andrew Van Praagh
  • DAPTOMYCIN FOR THE TREATMENT OF BIOFILM AND CATHETER SALVAGE
    Publication number: 20090298750
    Abstract: Daptomycin can be used for biofilm treatment (particularly central venous catheter salvage for S. epidermidis infected catheters). Catheter salvage with daptomycin shows rapid cidality, activity against stationary phase bacteria, and penetration and activity in biofilms. The present inventions provide formulations, methods, and articles of manufacture useful for biofilm treatment or catheter salvage involving daptomycin. Particular formulations include daptomycin in lactated Ringer's solution having a rapid kill curve against the bacteria of the biofilm.
    Type: Application
    Filed: May 31, 2006
    Publication date: December 3, 2009
    Inventors: Jeffrey Alder, Jared Silverman, Lawrence Mortin, Andrew Van Praagh
  • Novel Lipopeptides as Antibacterial Agents
    Publication number: 20090011977
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Application
    Filed: June 27, 2008
    Publication date: January 8, 2009
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
  • Novel Lipopeptides as Antibacterial Agents
    Publication number: 20080287347
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Application
    Filed: June 27, 2008
    Publication date: November 20, 2008
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
  • Lipopeptides as antibacterial agents
    Patent number: 7408025
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: August 5, 2008
    Assignee: Cubist Pharmaceuticals, Inc.
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
  • Lipopeptides as antibacterial agents
    Patent number: 7335725
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: February 26, 2008
    Assignee: Cubist Pharmaceuticals, Inc.
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xian Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
  • Novel lipopeptides as antibacterial agents
    Publication number: 20050203006
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Application
    Filed: May 4, 2005
    Publication date: September 15, 2005
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xian Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan Watson, Yan Zhang
  • Lipopeptides as antibacterial agents
    Patent number: 6911525
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: June 28, 2005
    Assignee: Cubist Pharmaceuticals, Inc.
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xian Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
  • Lipopeptides as antibacterial agents
    Patent number: 6794490
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: September 21, 2004
    Assignee: Cubist Pharmaceuticals, Inc.
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xian Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
  • Novel lipopeptides as antibacterial agents
    Publication number: 20040067878
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Application
    Filed: December 15, 2000
    Publication date: April 8, 2004
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
  • Novel lipopeptides as antibacterial agents
    Publication number: 20020058785
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Application
    Filed: December 15, 2000
    Publication date: May 16, 2002
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
  • Novel lipopeptides as antibacterial agents
    Publication number: 20020025924
    Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.
    Type: Application
    Filed: December 15, 2000
    Publication date: February 28, 2002
    Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang