Patents by Inventor Jari Kaikkonen
Jari Kaikkonen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20110111404Abstract: Genes, SNP markers and haplotypes of susceptibility or predisposition to T2D and subdiagnosis of T2D and related medical conditions are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for T2D, obesity and related phenotypes using polymorphisms in the risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of T2D and related traits. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of T2D. Novel methods for prevention and treatment of metabolic diseases such as T2D based on the disclosed T2D genes, polypeptides and related pathways are also disclosed.Type: ApplicationFiled: August 31, 2010Publication date: May 12, 2011Inventors: Jukka T. Salonen, Jelena Hyppönen, Jari Kaikkonen, Mia Pirskanen, Pekka Uimari, Juha-Matti Aaalto
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Publication number: 20110111405Abstract: Genes, SNP markers and haplotypes of susceptibility or predisposition to T2D and subdiagnosis of T2D and related medical conditions are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for T2D, obesity and related phenotypes using polymorphisms in the risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of T2D and related traits. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of T2D. Novel methods for prevention and treatment of metabolic diseases such as T2D based on the disclosed T2D genes, polypeptides and related pathways are also disclosed.Type: ApplicationFiled: August 31, 2010Publication date: May 12, 2011Inventors: Jukka T. Salonen, Jelena Hyppönen, Jari Kaikkonen, Mia Pirskannen, Pekka Uimari, Juha-Matti Aalto
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Patent number: 7901885Abstract: Genes, SNP markers and haplotypes of susceptibility or predisposition to T2D and subdiagnosis of T2D and related medical conditions are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for T2D, obesity and related phenotypes using polymorphisms in the risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of T2D and related traits. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of T2D. Novel methods for prevention and treatment of metabolic diseases such as T2D based on the disclosed T2D genes, polypeptides and related pathways are also disclosed.Type: GrantFiled: May 9, 2007Date of Patent: March 8, 2011Assignee: DSM IP Assets B.V.Inventors: Jukka T. Salonen, Jelena Hyppönen, Jari Kaikkonen, Mia Pirskanen, Pekka Uimari, Juha-Matti Aalto
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Publication number: 20070292412Abstract: Genes, SNP markers and haplotypes of susceptibility or predisposition to T2D and subdiagnosis of T2D and related medical conditions are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for T2D, obesity and related phenotypes using polymorphisms in the risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of T2D and related traits. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of T2D. Novel methods for prevention and treatment of metabolic diseases such as T2D based on the disclosed T2D genes, polypeptides and related pathways are also disclosed.Type: ApplicationFiled: May 9, 2007Publication date: December 20, 2007Applicant: Oy Jurilab LtdInventors: Jukka Salonen, Jelena Hypponen, Jari Kaikkonen, Mia Pirskanen, Pekka Uimari, Juha-Matti Aalto
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Patent number: 7211387Abstract: This invention is directed to a DNA sequence comprising a nucleotide sequence encoding a variant paraoxonase protein and to said variant paraoxonase protein as well as a method and a kit for detecting a risk of cancer, coronary or cerebrovascular disease, hypertension, type 2 diabetes, dementia, joint arthrosis, cataract, or sensitivity to organophosphorus compounds in a subject, the method comprising isolating genomic DNA from said subject, determining the allelic pattern for the codon 102 of the paraoxonase encoding PON1 gene in the genomic DNA, identification of Ile101Val mutation indicating said risk being increased and for targeting paraoxonase activity modulating therapies. Further this invention relates to transgenic animals comprising a human DNA molecule encoding said variant paraoxonase and to a method of phenotype-targeted gene sequencing.Type: GrantFiled: October 24, 2003Date of Patent: May 1, 2007Assignee: OY Jurilab Ltd.Inventors: Jukka T. Salonen, Marja Marchesani, Tomi-Pekka Tuomainen, Jari Kaikkonen
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Patent number: 7039420Abstract: The present invention relates to a method for activating actions. The method comprises the steps of defining an action, a portable device (9) related to it and, as a condition for activating the action, at least one item of position data, and determining the position of the portable device (9). When the position of the portable device (9) corresponds to the position data defined in an action, said action is activated. In the method, the information about actions is processed in a server (2), from which a data transmission connection can be set up to the device, in which the action data is transmitted from the server (2), to be activated.Type: GrantFiled: March 11, 2003Date of Patent: May 2, 2006Assignee: Nokia CorporationInventors: Harri Koskinen, Kimmo Kauvo, Teppo Kivento, Jarkko Leino, Janne Karjalainen, Jari Kaikkonen, Kim Simelius, Tommi Ojala
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Publication number: 20040192311Abstract: The present invention relates to a method for activating actions. The method comprises the steps of defining an action, a portable device (9) related to it and, as a condition for activating the action, at least one item of position data, and determining the position of the portable device (9). When the position of the portable device (9) corresponds to the position data defined in an action, said action is activated. In the method, the information about actions is processed in a server (2), from which a data transmission connection can be set up to the device, in which the action data is transmitted from the server (2), to be activated.Type: ApplicationFiled: March 11, 2003Publication date: September 30, 2004Applicant: Nokia CorporationInventors: Harri Koskinen, Kimmo Kauvo, Teppo Kivento, Jarkko Leino, Janne Karjalainen, Jari Kaikkonen, Kim Simelius, Tommi Ojala
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Publication number: 20040142349Abstract: This invention is directed to a DNA sequence comprising a nucleotide sequence encoding a variant paraoxonase protein and to said variant paraoxonase protein as well as a method and a kit for detecting a risk of cancer, coronary or cerebrovascular disease, hypertension, type 2 diabetes , dementia, joint arthrosis, cataract, or sensitivity to organophosphorus compounds in a subject, the method comprising isolating genomic DNA from said subject, determining the allelic pattern for the codon 102 of the paraoxonase encoding PON1 gene in the genomic DNA, identification of Ile101Val mutation indicating said risk being increased and for targeting paraoxonase activity modulating therapies. Further this invention relates to transgenic animals comprising a human DNA molecule encoding said variant paraoxonase and to a method of phenotype-targeted gene sequencing.Type: ApplicationFiled: October 24, 2003Publication date: July 22, 2004Applicant: Oy Jurilab Ltd.Inventors: Jukka T. Salonen, Marja Marchesani, Tomi-Pekka Tuomainen, Jari Kaikkonen
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Patent number: 6740746Abstract: This invention is directed to a DNA sequence comprising a nucleotide sequence encoding a variant paraoxonase protein and to said variant paraoxonase protein as well as a method and a kit for detecting a risk of cancer, coronary or cerebrovascular disease, hypertension, type 2 diabetes, dementia, joint arthrosis, cataract, or sensitivity to organophosphorus compounds in a subject, the method comprising isolating genomic DNA from said subject, determining the allelic pattern for the codon 102 of the paraoxonase encoding PON1 gene in the genomic DNA, identification of Ile101Val mutation indicating said risk being increased and for targeting paraoxonase activity modulating therapies. Further this invention relates to transgenic animals comprising a human DNA molecule encoding said variant paraoxonase and to a method of phenotype-targeted gene sequencing.Type: GrantFiled: March 20, 2001Date of Patent: May 25, 2004Assignee: Oy Jurilab Ltd.Inventors: Jukka T. Salonen, Marja Marchesani, Tomi-Pekka Tuomainen, Jari Kaikkonen
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Publication number: 20030003453Abstract: This invention is directed to a DNA sequence comprising a nucleotide sequence encoding a variant paraoxonase protein and to said variant paraoxonase protein as well as a method and a kit for detecting a risk of cancer, coronary or cerebrovascular disease, hypertension, type 2 diabetes , dementia, joint arthrosis, cataract, or sensitivity to organophosphorus compounds in a subject, the method comprising isolating genomic DNA from said subject, determining the allelic pattern for the codon 102 of the paraoxonase encoding PON1 gene in the genomic DNA, identification of Ile101Val mutation indicating said risk being increased and for targeting paraoxonase activity modulating therapies. Further this invention relates to transgenic animals comprising a human DNA molecule encoding said variant paraoxonase and to a method of phenotype-targeted gene sequencing.Type: ApplicationFiled: March 20, 2001Publication date: January 2, 2003Inventors: Jukka T. Salonen, Marja Marchesani, Tomi-Pekka Tuomainen, Jari Kaikkonen
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Patent number: 6456936Abstract: The present invention relates to a method for storing position data, in particular for use in a navigation and/or road information service system. In order to simplify considerably the storage of position data, in particular for entering position data for setting up an electronically stored address book, the invention provides that the current position is detected with the aid of a position-finding system, the current position is allocated a title, and the current position is stored with the allocated title such that the stored position can be selected with the aid of the associated title.Type: GrantFiled: May 13, 1999Date of Patent: September 24, 2002Assignee: Nokia Mobile Phones LimitedInventors: Ralph Neukirchen, Jari Kaikkonen, Jarkko Lempio, Kimmo Kauvo
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Patent number: 6240363Abstract: The invention relates to a navigation method, in particular for vehicles, in which a route (R) from a starting point (z1) to a destination (zn) is determined and stored, in which the current position (z(t)) is determined, and in which direction information corresponding to the route (R) is indicated. In order to allow the user to be guided to his destination, if he leaves the route, without using map material, the invention provides for a direction which leads back to the route to be indicated, if the current position is not on the route.Type: GrantFiled: January 27, 1999Date of Patent: May 29, 2001Assignee: Nokia Mobile Phones, LimitedInventors: Wolfgang Theimer, Heikki Laine, Hannu Hakala, Jari Kaikkonen, Harri Koskinen, Harri Valio