Patents by Inventor Jari Lewandowski
Jari Lewandowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220330584Abstract: This specification relates to a process for preparing a purified human milk oligosaccharide (“HMO”) from an HMO-containing solution (e.g., a fermentation broth) by a process comprising removal of an antifoam agent, and a product of such a process.Type: ApplicationFiled: August 28, 2020Publication date: October 20, 2022Inventors: Juho JARVINEN, Hannu KOIVIKKO, Antti KOPONEN, Jyrki KUUSISTO, Jari LEWANDOWSKI, Tero MENTUNEN
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Publication number: 20220081732Abstract: This specification relates to a process for preparing fucose from a human milk oligosaccharide (“HMO”) comprising a fucose moiety, as well as L-fucose compositions prepared by such a process.Type: ApplicationFiled: January 20, 2020Publication date: March 17, 2022Inventors: Jari LEWANDOWSKI, Juha NURMI, Hannu KOIVIKKO, Jyrki KUUSISTO, Nina NURMI, Jani SIITONEN, Juho JÄRVINEN
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Patent number: 9777342Abstract: The invention relates to a method of separating and recovering xylose from a xylose-containing plant-based solution. The method is performed in a chromatographic separation system, which comprises one or more weak base anion exchange resins and optionally one or more other resins selected from strong acid cation exchange resins and weak acid cation exchange resins, by passing the solution through the separation system, followed by recovering at least one fraction enriched in xylose. Optionally, a rhamnose fraction may also be recovered.Type: GrantFiled: September 19, 2013Date of Patent: October 3, 2017Assignee: DUPONT NUTRITION BIOSCIENCES APSInventors: Jari Lewandowski, Nina Nurmi, Jari Mattila, Kari Laiho, Kati Kekalainen
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Publication number: 20150247211Abstract: The invention relates to a method of separating and recovering xylose from a xylose-containing plant-based solution. The method is performed in a chromatographic separation system, which comprises one or more weak base anion exchange resins and optionally one or more other resins selected from strong acid cation exchange resins and weak acid cation exchange resins, by passing the solution through the separation system, followed by recovering at least one fraction enriched in xylose. Optionally, a rhamnose fraction may also be recovered.Type: ApplicationFiled: September 19, 2013Publication date: September 3, 2015Inventors: Jari Lewandowski, Nina Nurmi, Jari Mattila, Kari Laiho, Kati Kekalainen
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Patent number: 9109265Abstract: A process for the separation of a xylose-containing, lignosulphonate-containing Ca-sulfite spent liquor is provided. The process comprises a first step of: (A) chromatographic separation of the Ca- or Mg-sulfite spent liquor using a single pass through a batch-type long resin bed chromatography column having a strong acid cation exchange resin as a separation medium. The ratio of the bed length:mean resin bead diameter of the column is 10,000-40,000. This step yields •a first xylose-rich fraction having a xylose content 50-70 wt. % based on dry solids and • a lignosulphonate-rich fraction. The process further comprises a step of: (B) crystallizing xylose from the first xylose rich fraction by using a crystallization method comprising (i) boiling crystallization; (ii) cooling crystallization or (iii) a combination of (i) and (ii) to obtain a first batch of crystalline xylose and a first xylose run-off.Type: GrantFiled: June 26, 2008Date of Patent: August 18, 2015Assignee: DUPONT NUTRITION BIOSCIENCES APSInventors: Heikki Heikkila, Jari Lewandowski
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Patent number: 9068236Abstract: The present invention relates to a process for the production of xylose and dissolving pulp from xylan-containing biomass, such as hardwood. The invention is based on prehydrolysis of the xylan-containing biomass with SO2 in specified conditions, followed by chromatographic fractionation, nanofiltration or precipitation crystallization of the xylose-containing prehydrolyzate to obtain a xylose product having a xylose content of at least 55% on DS. The dissolving pulp obtained from the process can be used for example for the production of viscose.Type: GrantFiled: October 20, 2009Date of Patent: June 30, 2015Assignee: Dupont Nutrition Biosciences APSInventors: Heikki Heikkila, Jari Lewandowski, Mirja Lindroos, Pia Saari
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Patent number: 8921541Abstract: The invention relates to an improved nanofiltration process for separating and recovering components, such as sugars and sugar alcohols from multicomponent mixtures. The process of the invention is characterized by collecting the nanofiltration retentate/permeate in several fractions with different purity, optional recycling of at least one of the collected nanofiltration retentate/permeate fractions to the nanofiltration and recovering the desired component from the nanofiltration permeate/retentate fractions by different methods. In one embodiment of the invention, the process comprises a combination of nanofiltration and chromatography.Type: GrantFiled: May 29, 2007Date of Patent: December 30, 2014Assignee: DuPont Nutritional Biosciences APSInventors: Heikki Heikkila, Hannu Koivikko, Jari Lewandowski, Mika Manttari, Jari Mattila
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Patent number: 8192629Abstract: The present invention relates to a chromatographic separation process for fractionating betaine-containing solutions by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The process provides improved separation capacity and separation efficiency without affecting the yield or purity of betaine or other products. The process can especially be applied to sequential SMB separation systems.Type: GrantFiled: February 24, 2010Date of Patent: June 5, 2012Assignee: Danisco A/SInventors: Jyrki Airaksinen, Heikki Heikkilä, Jari Lewandowski, Kari Laiho
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Publication number: 20110245487Abstract: The invention relates to a multiprofile chromatographic sequential SMB process of separating and recovering betaine and sucrose from concentrated raw juice or thick juice. In the process of the invention, the betaine subprofile and the residual subprofile of successive separation profiles are overlapping. A sucrose fraction and a betaine fraction containing also residual components are recovered. Betaine is further separated from the betaine fraction for example by chromatographic processes.Type: ApplicationFiled: March 29, 2011Publication date: October 6, 2011Applicant: DANISCO A/SInventors: Jyrki AIRAKSINEN, Hannu PAANANEN, Jari LEWANDOWSKI, Kari LAIHO
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Publication number: 20110245491Abstract: The invention relates to a three-profile chromatographic sequential SMB process of separating and recovering products such as sugars and betaine from multicomponent feed solutions. In the process of the invention, product fractions and optionally recycle fractions are collected from several positions of the chromatographic separation system. The process of the invention may be applied to the separation of sucrose and betaine from sugar beet based solutions and to the separation of sugars, e.g. xylose, from plant-based hydrolysates, for example.Type: ApplicationFiled: March 29, 2011Publication date: October 6, 2011Applicant: Danisco A/SInventors: Jyrki AIRAKSINEN, Hannu PAANANEN, Jari LEWANDOWSKI, Kari LAIHO
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Publication number: 20110192560Abstract: The present invention relates to a process for the production of xylose and dissolving pulp from xylan-containing biomass, such as hardwood. The invention is based on prehydrolysis of the xylan-containing biomass with SO2 in specified conditions, followed by chromatographic fractionation, nanofiltration or precipitation crystallization of the xylose-containing prehydrolyzate to obtain a xylose product having a xylose content of at least 55% on DS. The dissolving pulp obtained from the process can be used for example for the production of viscose.Type: ApplicationFiled: October 20, 2009Publication date: August 11, 2011Applicant: DANISCO A/SInventors: Heikki Heikkila, Jari Lewandowski, Mirja Lindroos, Pia Saari
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Publication number: 20110172411Abstract: A process for the separation of a xylose-containing, lignosulphonate-containing Ca-sulfite spent liquor is provided. The process comprises a first step of: (A) chromatographic separation of the Ca- or Mg-sulfite spent liquor using a single pass through a batch-type long resin bed chromatography column having a strong acid cation exchange resin as a separation medium. The ratio of the bed length:mean resin bead diameter of the column is 10,000-40,000. This step yields •a first xylose-rich fraction having a xylose content 50-70 wt. % based on dry solids and • a lignosulphonate-rich fraction. The process further comprises a step of: (B) crystallizing xylose from the first xylose rich fraction by using a crystallization method comprising (i) boiling crystallization; (ii) cooling crystallization or (iii) a combination of (i) and (ii) to obtain a first batch of crystalline xylose and a first xylose run-off.Type: ApplicationFiled: June 26, 2008Publication date: July 14, 2011Applicant: DANISCO A/SInventors: Heikki Heikkila, Jari Lewandowski
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Patent number: 7959811Abstract: The present invention relates to a chromatographic separation process for fractionating solutions containing sugars, sugar alcohols, sugar acids and/or betaine by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The starting solutions are typically multicomponent plant-based extracts and hydrolysates, stillages, and fermentation products and derivatives thereof. The process prow vides improved separation capacity and separation efficiency without affecting the yield or purity of product components, such as sugars, sugar alcohols, sugar acids, and betaine. The process can especially be applied to sequential SMB separation systems.Type: GrantFiled: February 24, 2010Date of Patent: June 14, 2011Assignee: Danisco A/SInventors: Jyrki Airaksinen, Heikki Heikkilä, Jari Lewandowski, Kari Laiho, Päivi Sarmala
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Publication number: 20100212662Abstract: The present invention relates to a chromatographic separation process for fractionating betaine-containing solutions by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The process provides improved separation capacity and separation efficiency without affecting the yield or purity of betaine or other products. The process can especially be applied to sequential SMB separation systems.Type: ApplicationFiled: February 24, 2010Publication date: August 26, 2010Applicant: DANISCO A/SInventors: Jyrki AIRAKSINEN, Heikki HEIKKILA, Jari LEWANDOWSKI, Kari LAIHO
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Publication number: 20100213130Abstract: The present invention relates to a chromatographic separation process for fractionating solutions containing sugars, sugar alcohols, sugar acids and/or betaine by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The starting solutions are typically multicomponent plant-based extracts and hydrolysates, stillages, and fermentation products and derivatives thereof. The process prow vides improved separation capacity and separation efficiency without affecting the yield or purity of product components, such as sugars, sugar alcohols, sugar acids, and betaine. The process can especially be applied to sequential SMB separation systems.Type: ApplicationFiled: February 24, 2010Publication date: August 26, 2010Applicant: DANISCO A/SInventors: Jyrki AIRAKSINEN, Heikki HEIKKILA, Jari LEWANDOWSKI, Kari LAIHO, Päivi SARMALA
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Publication number: 20090270609Abstract: The invention relates to an improved nanofiltration process for separating and recovering components, such as sugars and sugar alcohols from multicomponent mixtures. The process of the invention is characterized by collecting the nanofiltration retentate/permeate in several fractions with different purity, optional recycling of at least one of the collected nanofiltration retentate/permeate fractions to the nanofiltration and recovering the desired component from the nanofiltration permeate/retentate fractions by different methods. In one embodiment of the invention, the process comprises a combination of nanofiltration and chromatography.Type: ApplicationFiled: May 29, 2007Publication date: October 29, 2009Applicant: DANISCO A/SInventors: Heikki Heikkila, Hannu Koivikko, Jari Lewandowski, Mika Manttari, Jari Mattila
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Patent number: 7303682Abstract: The present invention relates to a fluid distributing device for distributing fluid into a column and to a fluid collecting device for collecting fluid from a column. The invention relates also to methods of using the devices of the present invention. The distributing device and/or the collecting device of the present invention can be used in fixed or fluidized bed reactors or columns, such as chromatographic separation columns, ion exchange columns, adsorption columns etc. A fluid distributing device comprises a) a first fluid conveying system; and b) a distributing plate, which comprises i) first means for fluid transfer for dividing the fluid flow coming from the delivering points into several partial fluid flows and for distributing the partial fluid flows into the column; and ii) first means for controlling of the partial fluid flows by differential pressure in the first means for fluid transfer.Type: GrantFiled: December 13, 2005Date of Patent: December 4, 2007Assignee: Finnfeeds Finland OYInventors: Hannu Paananen, Heikki Heikkilä, Jari Lewandowski, Esko Varteva
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Patent number: 7229558Abstract: A method for fractionating a solution into two or more fractions. More particularly the invention relates to a method for fractionating a solution by a chromatographic simulated moving bed (SMB) process in which the dissolved substances present in the feedstock are separated in the partial packed beds, and the formed separation profile is circulated more than once or less than once through the chromatographic separation loop during one cycle.Type: GrantFiled: January 11, 2005Date of Patent: June 12, 2007Assignee: Danisco Sweeteners OyInventors: Heikki Heikkilä, Jari Lewandowski, Jarmo Kuisma
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Publication number: 20070112187Abstract: The invention relates to a process of recovering arabinose and optionally other monosaccharides from vegetable fiber rich in heteropolymeric arabinose, such as gum arabic. Said other monosaccharides are typically selected from galactose and rhamnose. The process of the invention comprises controlled hydrolysis of the arabinose-rich vegetable fiber and fractionation of the hydrolysis product to obtain a fraction enriched in arabinose and optionally other product fractions followed by crystallization of arabinose. The invention also relates to a novel method of crystallizing arabinose from biomass-derived material. Furthermore, the invention relates to novel crystalline L-arabinose.Type: ApplicationFiled: October 29, 2004Publication date: May 17, 2007Inventors: Heikki Heikkila, Hannu Koivikko, Juha Nurmi, Jari Mattila, Pia Saari, Nina Nurmi, Paivi Sarmala, Mirja Lindroos, Jari Lewandowski
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Publication number: 20060124550Abstract: The present invention relates to a fluid distributing device for distributing fluid into a column and to a fluid collecting device for collecting fluid from a column. The invention relates also to methods of using the devices of the present invention. The distributing device and/or the collecting device of the present invention can be used in fixed or fluidized bed reactors or columns, such as chromatographic separation columns, ion exchange columns, adsorption columns etc. A fluid distributing device comprises a) a first fluid conveying system; and b) a distributing plate, which comprises i) first means for fluid transfer for dividing the fluid flow coming from the delivering points into several partial fluid flows and for distributing the partial fluid flows into the column; and ii) first means for controlling of the partial fluid flows by differential pressure in the first means for fluid transfer.Type: ApplicationFiled: December 13, 2005Publication date: June 15, 2006Applicant: Finnfeeds Finland OYInventors: Hannu Paananen, Heikki Heikkila, Jari Lewandowski, Esko Varteva