Patents by Inventor Jarkko Eskola

Jarkko Eskola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7513983
    Abstract: Methods and insulator electrode devices for performing electrochemical reactions are disclosed. The devices consist of high specific surface area electrodes based on a channeled conducting base material that has been coated with an organic or inorganic insulating film or multiple layers of such films. The chemical reactions are exemplified by exciting one or several label compounds into an excited state which is spontaneously de-excited by emission of ultraviolet, visible or infrared light, in aqueous solution. This provides the basis for reproducible analytical applications in bioaffinity assays such as immunoassays and DNA-probing assays.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: April 7, 2009
    Assignee: Labmaster Ltd.
    Inventors: Timo Ala-Kleme, Philip Canty, Jarkko Eskola, Timo Korpela, Sakari Kulmala, Piia Vainio
  • Publication number: 20060096866
    Abstract: Methods and insulator electrode devices for performing electrochemical reactions are disclosed. The devices consist of high specific surface area electrodes based on a channeled conducting base material that has been coated with an organic or inorganic insulating film or multiple layers of such films. The chemical reactions are exemplified by exciting one or several label compounds into an excited state which is spontaneously de-excited by emission of ultraviolet, visible or infrared light, in aqueous solution. This provides the basis for reproducible analytical applications in bioaffinity assays such as immunoassays and DNA-probing assays.
    Type: Application
    Filed: December 5, 2005
    Publication date: May 11, 2006
    Applicant: LABMASTER LTD.
    Inventors: Timo Ala-Kleme, Philip Canty, Jarkko Eskola, Timo Korpela, Sakari Kulmala, Piia Vainio
  • Patent number: 7005108
    Abstract: Methods and insulator electrode devices for performing electrochemical reactions are disclosed. The devices consist of high specific surface area electrodes based on a channeled conducting base material that has been coated with an organic or inorganic insulating film or multiple layers of such films. The chemical reactions are exemplified by exciting one or several label compounds into an excited state which is spontaneously de-excited by emission of ultraviolet, visible or infrared light, in aqueous solution. This provides the basis for reproducible analytical applications in bioaffinity assays such as immunoassays and DNA-probing assays.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: February 28, 2006
    Assignee: Labmaster Ltd.
    Inventors: Timo Ala-Kleme, Philip Canty, Jarkko Eskola, Timo Korpela, Sakari Kulmala, Piia Vainio
  • Publication number: 20040101868
    Abstract: The inventions deals with determination of the human hemochromatosis gene (HFE) mutation (C282Y of HFE protein), responsible for the disease of hereditary hemochromatosis. The invention is important in diagnosis and risk assessment for this disease. The method consists of a single-tube high-throughput PCR assay for the detection of C282Y. We invented that it is advantageously possible to combine three concepts each known separately in prior art from different sources: allele specific PCR, mutagenically separated PCR, and amplicon identification by specific dissociation curves. Analysis can be performed in either a conventional or fluorescence-detecting thermocycler using the same primers, reactant constituents and cycling protocol. PCR products are identified either by their length or melting temperature (Tm). Primer cross reactions are prevented by deliberate primer: primer and primer: template mismatches.
    Type: Application
    Filed: February 21, 2003
    Publication date: May 27, 2004
    Inventors: Veli Kairisto, Gerard Donohoe, Jarkko Eskola, Timo Korpela
  • Patent number: 6645776
    Abstract: The excitation of label molecules usable in chemical and biochemical analysis by electrical pulses at electrodes covered with a thin insulating film, and the use of such electrodes in chemical, clinical and biochemical analysis. The electrodes include a conducting base material that has been coated with an organic or inorganic insulating film or multiple layers of such films, so that either one or several label compounds can be excited to an excited state which is deexcited by emission of ultraviolet, visible or infrared light, in aqueous solution providing the basis for reproducible analytical applications in bioaffinity assays such as immunoassays and DNA-probing assays.
    Type: Grant
    Filed: February 9, 2001
    Date of Patent: November 11, 2003
    Assignee: Labmaster Oy
    Inventors: Sakari Kulmala, Timo Ala-Kleme, Jarkko Eskola, Timo Korpela
  • Publication number: 20030192780
    Abstract: Methods and insulator electrode devices for performing electrochemical reactions are disclosed. The devices consist of high specific surface area electrodes based on a channeled conducting base material that has been coated with an organic or inorganic insulating film or multiple layers of such films. The chemical reactions are exemplified by exciting one or several label compounds into an excited state which is spontaneously de-excited by emission of ultraviolet, visible or infrared light, in aqueous solution. This provides the basis for reproducible analytical applications in bioaffinity assays such as immunoassays and DNA-probing assays.
    Type: Application
    Filed: April 24, 2002
    Publication date: October 16, 2003
    Inventors: Timo Ala-Kleme, Philip Canty, Jarkko Eskola, Timo Korpela, Sakari Kulmala, Piia Vainio
  • Publication number: 20020081749
    Abstract: The excitation of label molecules usable in chemical and biochemical analysis by electrical pulses at electrodes covered with a thin insulating film, and the use of such electrodes in chemical, clinical and biochemical analysis. The electrodes include a conducting base material that has been coated with an organic or inorganic insulating film or multiple layers of such films, so that either one or several label compounds can be excited to an excited state which is deexcited by emission of ultraviolet, visible or infrared light, in aqueous solution providing the basis for reproducible analytical applications in bioaffinity assays such as immunoassays and DNA-probing assays.
    Type: Application
    Filed: February 9, 2001
    Publication date: June 27, 2002
    Inventors: Sakari Kulmala, Timo Ala-Kleme, Jarkko Eskola, Timo Korpela
  • Patent number: 6251690
    Abstract: The excitation of label molecules usable in chemical and biochemical analysis by electrical pulses at electrodes covered with a thin insulating film, and the use of such electrodes in chemical, clinical and biochemical analysis. The electrodes include a conducting base material that has been coated with an organic or inorganic insulating film or multiple layers of such films, so that either one or several label compounds can be excited to an excited state which is deexcited by emission of ultraviolet, visible or infrared light, in aqueous solution providing the basis for reproducible analytical applications in bioaffinity assays such as immunoassays and DNA-probing assays.
    Type: Grant
    Filed: July 21, 1999
    Date of Patent: June 26, 2001
    Inventors: Sakari Kulmala, Timo Ala-Kleme, Jarkko Eskola, Timo Korpela