Abstract: An apparatus and a system for filtering a liquid sample in a sample well (310) by transferring the liquid out of the sample well (310) through a filter member (320) situated at a bottom part of the sample well (310). The apparatus and the system include a syringe (100), and a seal member (200) arranged around a nozzle (140) of the syringe (100) in such a way that the syringe (100) is adjustable in connection with an upper part of the sample well (310) in a substantially airtight manner. A method for filtering a liquid sample and use of the system for filtering eluted blood are also disclosed.

Abstract: Instrumentation and a method for efficient and reliable assaying and measuring samples. The teachings include an automated self-contained instrument, wherein the samples are located on wells of sample plates, and the instrument includes a plurality of units for processing or storing sample plates. The instrument may includes at least one dispensing unit for dispensing reagents or other assay components to the sample wells, at least two units for simultaneously processing or storing a plurality of sample plates, at least one unit for removing substance from the sample wells, and one or several measurement units for optically measuring samples in at least two measurement modes. Further, the instrument includes a manipulator for moving the sample plates in three orthogonal directions or combinations thereof and for rotating the sample plates in relation to a vertical axis for transferring the sample plates to the units.

Abstract: An apparatus and a system for filtering a liquid sample in a sample well (310) by transferring the liquid out of the sample well (310) through a filter member (320) situated at a bottom part of the sample well (310). The apparatus and the system include a syringe (100), and a seal member (200) arranged around a nozzle (140) of the syringe (100) in such a way that the syringe (100) is adjustable in connection with an upper part of the sample well (310) in a substantially airtight manner. A method for filtering a liquid sample and use of the system for filtering eluted blood are also disclosed.

Abstract: One object of the invention is to provide instrumentation and a method for efficient and reliable assaying and measuring samples. The teachings include an automated self-contained instrument for assaying and measuring samples, wherein the samples are located on wells of sample plates, and the instrument comprises a plurality of units for processing or storing sample plates. The instrument according to the teaching may comprise at least one dispensing unit for dispensing reagents or other assay components to the sample wells, at least two units for simultaneously processing or storing a plurality of sample plates, at least one unit for removing substance from the sample wells, and one or several measurement units, the measurement unit(s) providing a capability for the instrument to optically measure samples in at least two measurement modes.

Abstract: This invention relates generally to the processing of measured data. Especially the invention applies to the binning procedure of data which is measured with a CCD (Charge-Coupled Device) sensor unit. The invention is preferably used in photometrics for measuring radiation from samples on a well plate. It is the objective of the present invention to create a solution, in which a good signal-to-noise value is achieved, and the measuring results of the neighbouring sample wells can still be well separated. This objective is achieved in photometrics application by selecting the binning factor on the basis of position and size of sample wells on a well plate (530, 550). With the present invention it is possible to achieve a maximal signal-to-noise ratio, because all pixels within the image area of one sample are accumulated. However, since the pixels between the sample images are not accumulated with the pixels within the sample images (526, 546), the problem of interference between samples can be avoided.

Abstract: An imaging device for biochemical or medical samples, the pulse mode light source of which incorporates flash lamps and a rotating mirror in an inclined position, the said mirror reflecting the light emitted by each flash lamp in turn along the same optical path to the sample. The flash lamps are switched on alternately in phases and synchronised with the rotating mirror and the emission light chopper, which comprises two rotating discs. The turning mirror directs the light at the sample from above and/or below, in which case a double-acting transparent scattering plate can be used.