Abstract: Described are methods for safer nitric oxide delivery, as well as apparatuses for performing these methods. The methods may include detecting the presence or absence of a nasal cannula, and stopping the delivery of nitric oxide or providing an alert if the cannula is disconnected. The methods may also include purging the nasal cannula if it is reconnected after a disconnection or if it is replaced by a new cannula. Other methods pertain to automatic purging of the delivery conduit if the elapsed time between successive deliveries of therapeutic gas exceeds a predetermined period of time.

Abstract: The present invention provides clinical decision support that can be used with non-portable and portable systems when delivering and/or monitoring delivery of a therapeutic gas comprising nitric oxide to a patient. Further, clinical decision support can be used with non-portable and portable systems during delivery and/or monitoring of delivery of therapeutic gas when nebulized drugs may and/or may not be being delivered to a patient (e.g., when nebulizers are delivered upstream in the inspiratory limb of the breathing circuit, into a breathing gas delivery system, etc.).

Abstract: Described are methods for safer nitric oxide delivery, as well as apparatuses for performing these methods. The methods may include detecting the presence or absence of a nasal cannula, and stopping the delivery of nitric oxide or providing an alert if the cannula is disconnected. The methods may also include purging the nasal cannula if it is reconnected after a disconnection or if it is replaced by a new cannula. Other methods pertain to automatic purging of the delivery conduit if the elapsed time between successive deliveries of therapeutic gas exceeds a predetermined period of time.

Abstract: Described are methods for safer nitric oxide delivery, as well as apparatuses for performing these methods. The methods may include detecting the presence or absence of a nasal cannula, and stopping the delivery of nitric oxide or providing an alert if the cannula is disconnected. The methods may also include purging the nasal cannula if it is reconnected after a disconnection or if it is replaced by a new cannula. Other methods pertain to automatic purging of the delivery conduit if the elapsed time between successive deliveries of therapeutic gas exceeds a predetermined period of time.

Abstract: A non-invasive monitoring apparatus for end-tidal gas concentrations, and a method of use thereof, is described for the detection of endogenous gas concentrations, including respiratory gases, in exhaled breath.

Abstract: Described are methods and devices for therapeutic or medical gas delivery that utilize at least one proportional control valve and at least one binary control valve. The proportional control valve may be in series with the binary control valve to provide a valve combination capable of pulsing therapeutic gas at different flow rates, depending on the setting of the proportional control valve. Alternatively, the proportional control valve and binary control valve may be in parallel flow paths.

Abstract: The present invention provides devices and methods for calculating and monitoring oxygenation parameters during treatment with delivery of nitric oxide. The devices and methods of the present invention can calculate the oxygenation index based on measurements of mean airway pressure, saturation of oxygen and fraction of inspired oxygen derived from components of the present invention. Also described is a nitric oxide delivery device that incorporates a proximal pressure transducer.

Abstract: Described are methods and devices for therapeutic or medical gas delivery that utilize at least one proportional control valve and at least one binary control valve. The proportional control valve may be in series with the binary control valve to provide a valve combination capable of pulsing therapeutic gas at different flow rates, depending on the setting of the proportional control valve. Alternatively, the proportional control valve and binary control valve may be in parallel flow paths.

Abstract: Described are methods and apparatus for therapeutic or medical gas delivery that reset or zero the trigger sensor used to detect patient inspiration and expiration. The trigger sensor may be reset automatically during patient expiration to avoid interfering with drug delivery or the breath detection algorithm.

Abstract: Described are methods for safer nitric oxide delivery, as well as apparatuses for performing these methods. The methods may include detecting the presence or absence of a nasal cannula, and stopping the delivery of nitric oxide or providing an alert if the cannula is disconnected. The methods may also include purging the nasal cannula if it is reconnected after a disconnection or if it is replaced by a new cannula. Other methods pertain to automatic purging of the delivery conduit if the elapsed time between successive deliveries of therapeutic gas exceeds a predetermined period of time.

Abstract: An optimized system for providing medical support to a patient is disclosed. The system comprises a plurality of modular components that may be assembled to create a connection between a support machine and the patient wherein at least one of the modular components comprises an information tag for the storage of data and at least one of the modular components comprises an information sensor for the reading and transmission of the data. Once read and transmitted by the sensor, the data may be used to optimize the operation of the support machine.

Abstract: An arrangement and method for detecting spontaneous respiratory effort of a patient receiving ventilatory support by a breathing circuit. The nasal cannula control system includes a nasal cannula assembly having two distinct lumens. A different pressure sensor is positioned to detect the pressure difference between each of the two lumens, thereby determining the differential pressure from within the patient's nostrils and within a breathing mask. The nasal cannula control system includes a gas sampling system such that the amount of a monitored gas discharged or exhaled by the patient can be monitored using the same nasal cannula assembly used to generate the differential pressure signal.

Abstract: A multiple lumen nasal cannula that can be used to delivery two separate supplies of gases to a patient. The multiple lumen nasal cannula includes a first lumen for delivering a first gas and a second lumen for delivering a second gas. The first lumen includes support structure that reduces the tendency of the cannula to kink and lock the delivery of gas to a patient. The cannula assembly includes a mixing chamber positioned near the patient such that the two supplies of gas are not mixed until a location approximate to delivery to the patient. The nasal cannula assembly includes a connecting device that allows the two separate supplies of gas to be correctly delivered to the two different lumens of the nasal cannula.

Abstract: A differential pressure transducer determines pressure differentials between respiratory airflows and ambient airflows. Another determines pressure differentials between respiratory airflows and ambient airflows. And another determines pressure differentials between i) respiratory airflows received from a subject and ii) interface airflows received from an area near a cannula. Corresponding respiratory monitoring methods also determine the same.

Abstract: A cannula receive respiratory airflows and ambient airflows. Another receives respiratory airflows and interface airflows. And another receives i) respiratory airflows from a subject and ii) interface airflows from an area near the cannula. Corresponding respiratory monitoring methods also receive the same.

Abstract: A cannula receives respiratory airflows and ambient airflows and a differential pressure transducer determine pressures differentials between the respiratory airflows and the ambient airflows. Another receives respiratory airflows and interface airflows and a differential pressure transducer determine pressures differentials between the respiratory airflows and the interface airflows. And another receives i) respiratory airflows from a subject and ii) interface airflows from an area near the cannula; and a differential pressure transducer determines pressure differentials between the respiratory airflows and the interface airflows. Corresponding respiratory monitoring methods also receive and determine the same.

Abstract: A cannula receives i) first respiratory airflows and second respiratory airflows into separate chambers, and ii) ambient airflows. Another receives i) first respiratory airflows and second respiratory airflows into separate chambers, and ii) interface airflows. And another i) first respiratory airflows and second respiratory airflows into separate chambers from a subject, and ii) interface airflow from an area near a cannula. Corresponding respiratory monitoring methods receive the same.

Abstract: A cannula receives respiratory airflows, exhaled gases, and ambient airflows. Another receives respiratory airflows, exhaled gases, and interface airflows. And another receives i) respiratory airflows and exhaled gases from a subject, and ii) interface airflows from an area near a cannula. Corresponding respiratory monitoring methods receive the same.