Abstract: A formulation of composites having yeast-derived beta glucan particles (GPs) and water-insoluble or poorly-water-soluble low-molecular-weight compounds, such as medicaments or food supplements is disclosed. The composites can exhibit different crystallinity degrees depending on the formulation and, consequently, dissolution kinetics can be controlled. Yeast-derived beta glucan particles are used as carriers for the encapsulation and amorphization of insoluble or poorly water-soluble low-molecular-weight compounds; amorphous formulations exhibiting faster dissolution rates, and consequently, enhanced oral bioavailability. A method of preparation of the composites by spray drying is also disclosed.

Abstract: A device for perpendicular stratification of planary fibrous shapes, above all of fibrous web, comprising two synchronously moving elements, connected with the driving mechanism according to the invention consists in that the reciprocating moving elements are connected with their driving mechanism indirectly by the intermediary of at least one robust shaft rigidly fitted in bearings in a rigid framework of the machine, while one element is connected with the shaft rigidly or over flexible joints, and a second element is coupled by means of flexible joints with the same shaft or with another shaft. The driving mechanism can consist of one driving shaft with two crank assemblies arranged with a phase shift to one another. The flexible joints consist of flat steel springs with a width-to-thickness ratio more than 10.